Item | Information |
---|---|
CAS RN | 21609-90-5 |
Chemical Name | O-4-Bromo-2,5-dichlorophenyl O-methyl phenylphosphorothioate |
Substance ID | m-nite-21609-90-5_v1 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | To Guidance List |
UN GHS document (External link) | To UN GHS document |
FAQ(GHS classification results by the Japanese Government) | To FAQ |
List of Information Sources (Excel file) | List of Information Sources |
List of Definitions/Abbreviations | Definitions/Abbreviations |
Sample Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Sample SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | To OECD/eChemPortal (External link) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Explosives | Not classified (Not applicable) |
- |
- | - | There are no chemical groups associated with explosive properties present in the molecules. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Flammable gases | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Aerosols | Not classified (Not applicable) |
- |
- | - | Not aerosol products | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Oxidizing gases | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Gases under pressure | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Flammable liquids | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Flammable solids | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Self-reactive substances and mixtures | Not classified (Not applicable) |
- |
- | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Pyrophoric liquids | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Pyrophoric solids | Not classified |
- |
- | - | HSDB (2003) has a description that "it is stabilized at normal temperature", and it was thought that there was no spontaneous combustibility. Thus, it was defined as "out of Category". | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Self-heating substances and mixtures | Classification not possible |
- |
- | - | Test methods applicable to solid (melting point <= 140degC) substances are not available. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified |
- |
- | - | Stable to water (the water solubility is obtained) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
13 | Oxidizing liquids | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
14 | Oxidizing solids | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
15 | Organic peroxides | Not classified (Not applicable) |
- |
- | - | Organic compounds containing no -0-0- structure | FY2006 | GHS Classification Manual (10 Feb, 2006) |
16 | Corrosive to metals | Classification not possible |
- |
- | - | Test methods applicable to solid substances are not available. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
17 | Desensitized explosives | - |
- |
- | - | - | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 2 |
Danger |
H300 | P301+P310 P264 P270 P321 P330 P405 P501 |
Based on the rat LD50 = 31.1mg/kg obtained by statistically processing 8 data in JMPR (WHO Pesticide Residues Series 5, 1975) in the Priority 1 document, the substance was classified as Category 2. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Dermal) | Category 3 |
Danger |
H311 | P302+P352 P361+P364 P280 P312 P321 P405 P501 |
It was set as Category 3 according to rat LD50 = 800mg/kg (JMPR (WHO Pesticide Residues Series 5, 1975) of Priority 1 document). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Gases) | Not classified (Not applicable) |
- |
- | - | Solid (GHS definition) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Vapours) | Not classified (Not applicable) |
- |
- | - | The vapor pressure of this product is very low (it is 0.0000031Pa at 20degC), and it was considered to be difficult to carry out vapor exposure, it was out of a classification. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Category 3 |
Danger |
H331 | P304+P340 P403+P233 P261 P271 P311 P321 P405 P501 |
It was set as Category 3 based on 0.9mg/kg/4H which is the lower value among the rat LC50 = 0.9 and 1.65mg/kg/4H of JMPR (WHO Pesticide Residues Series 5, 1975) in Priority 1 document. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Skin corrosion/irritation | Not classified |
- |
- | - | In the test of the rabbit of JMPR (WHO Pesticide Residues Series 5, 1975), since it did not indicate skin stimulative to be also drug substances and a tablet, it considered as the outside of Category. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Serious eye damage/eye irritation | Category 2B |
Warning |
H320 | P305+P351+P338 P337+P313 P264 |
In the test of the rabbit, the eye irritations condition had disappeared in 72 hours after-exposure PDS (WHO/FAO, 1979). So it was set as Category 2B. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Skin sensitization | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Germ cell mutagenicity | Not classified |
- |
- | - | In the dominant fatality test of the mouse of JMPR (WHO Pesticide Residues Series 5, 1975), it was negative, and it is classified as the out of the Category. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Carcinogenicity | Not classified |
- |
- | - | In the long-term feed-mix administration test of mice by JMPR (WHO Pesticide Residues Series 5, 1975), and of rats by PDS (WHO/FAO, 1979), the carcinogenic resulting from the this product was not acknowledged. Therefore, it was carried out the outside of category. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Reproductive toxicity | Category 1B |
Danger |
H360 | P308+P313 P201 P202 P280 P405 P501 |
In three-generation studies in rats of JMPR (WHO Pesticide Residues Series 5, 1975) of Priority 1 document, the survival rate of baby animals was significantly decreased at the dose (60ppm) which any specific toxicity was not observed in parent animals. So it was set as Category 1B. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Specific target organ toxicity - Single exposure | Category 2 (nervous system) |
Warning |
H371 | P308+P311 P260 P264 P270 P405 P501 |
Since there is description that in HSDB (2003) and SITTIG (4th, 2002) of Priority 2 document, this product which is the organophosphorus insecticide has an inhibition of cholinesterase, and it affects the human nervous system, and it was considered as Category 2 (nervous systems). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible |
- |
- | - | Although erythrocyte (or brain) cholinesterase inhibition was observed in rat repeated oral administration test with different dosing periods (for 90 days and for two years)(JMPR (WHO Pesticide Residues Series 5, 1975) and PDS (WHO/FAO, 1979) in Priority 1 document), since distinct toxic symptom resulting from the this product was not observed, and target organ was not specified either, it could not be classified. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Aspiration hazard | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | Category 1 |
Warning |
H400 | P273 P391 P501 |
It was classified into Category 1 from 96-hour LC50=0.0019mg/L of Crustacea (Pink shrimp) (ECETOC TR 91, and 2003). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Hazardous to the aquatic environment Long term (Chronic) | Category 1 |
Warning |
H410 | P273 P391 P501 |
Classified into Category 1, since acute toxicity is Category 1, supposed not rapidly degrading (BIOWIN), and bioaccumulative (log Kow=6.31 (PHYSPROP Database, 2005)). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Hazardous to the ozone layer | - |
- |
- | - | - | - | - |
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