Item | Information |
---|---|
CAS RN | 7784-42-1 |
Chemical Name | Arsine |
Substance ID | m-nite-7784-42-1_v1 |
Download of Excel format | Excel file |
Item | Information |
---|---|
Guidance used for the classification (External link) | To Guidance List |
UN GHS document (External link) | To UN GHS document |
FAQ(GHS classification results by the Japanese Government) | To FAQ |
List of Information Sources (Excel file) | List of Information Sources |
List of Definitions/Abbreviations | Definitions/Abbreviations |
Sample Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Sample SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | To OECD/eChemPortal (External link) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Explosives | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Flammable gases | Category 1 |
Danger |
H220 | P210 P377 P381 P403 |
Based on the description in ICSC (2004): the lower explosion limit is 4.5vol%. Classified into Division 2.1 (UN#2188) (UN Recommendations on the Transport of Dangerous Goods) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Aerosols | Not classified (Not applicable) |
- |
- | - | Not aerosol products | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Oxidizing gases | Not classified |
- |
- | - | Classified into Division 2.1 and Division 2.3 (UN#2188) (UN Recommendations on the Transport of Dangerous Goods) | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Gases under pressure | Liquefied gas |
Warning |
H280 | P410+P403 | The boiling point is -62degC (ICSC (2004)) and the critical temperature is 100degC (HSDB (2006)), i.e., liquefied gas. Classified into Division 2.1 and Division 2.3 (UN#2188) (UN Recommendations on the Transport of Dangerous Goods). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Flammable liquids | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Flammable solids | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Self-reactive substances and mixtures | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Pyrophoric liquids | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Pyrophoric solids | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Self-heating substances and mixtures | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
13 | Oxidizing liquids | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
14 | Oxidizing solids | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
15 | Organic peroxides | Not classified (Not applicable) |
- |
- | - | Classified as "gas" according to GHS definition | FY2006 | GHS Classification Manual (10 Feb, 2006) |
16 | Corrosive to metals | Classification not possible |
- |
- | - | Test methods applicable to gas substances are not available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
17 | Desensitized explosives | - |
- |
- | - | - | - | - |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Dermal) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Gases) | Category 1 |
Danger |
H330 | P304+P340 P403+P233 P260 P271 P284 P310 P320 P405 P501 |
Based on the rat LC50 (inhalation of gas) value of 16.2ppm (4 hours). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Vapours) | Not classified (Not applicable) |
- |
- | - | Due to the fact that the substance is "gas" according to the GHS definition and inhalation of its vapour is not expected. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
1 | Acute toxicity (Inhalation: Dusts and mists) | Not classified (Not applicable) |
- |
- | - | Due to the fact that the substance is "gas" according to the GHS definition and inhalation of its dust/mist is not expected. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
2 | Skin corrosion/irritation | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
3 | Serious eye damage/eye irritation | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Respiratory sensitization | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
4 | Skin sensitization | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
5 | Germ cell mutagenicity | Classification not possible |
- |
- | - | No data available As for the health hazards, refer to "ID1075, Sodium Arsenate, CAS: 13464-38-5," "ID1088, Sodium Arsenite, CAS: 7784-46-5," "ID54, Arsenic, CAS: 7440-38-2" and "ID55, Diarsenic Trioxide (Arsenious Acid), CAS: 1327-53-3." |
FY2006 | GHS Classification Manual (10 Feb, 2006) |
6 | Carcinogenicity | Category 1A |
Danger |
H350 | P308+P313 P201 P202 P280 P405 P501 |
Due to the fact that the substance is classified as Category 1 (as ARSENIC AND ARSENIC COMPOUNDS) by IARC (1987) and Category K (as Arsenic Compounds, Inorganic) by NTP (2005). | FY2006 | GHS Classification Manual (10 Feb, 2006) |
7 | Reproductive toxicity | Classification not possible |
- |
- | - | No data available As for the health hazards, refer to "ID1075, Sodium Arsenate, CAS: 13464-38-5," "ID1088, Sodium Arsenite, CAS: 7784-46-5," "ID54, Arsenic, CAS: 7440-38-2" and "ID55, Diarsenic Trioxide (Arsenious Acid), CAS: 1327-53-3." |
FY2006 | GHS Classification Manual (10 Feb, 2006) |
8 | Specific target organ toxicity - Single exposure | Category 1 (central nervous system, blood system, cardiovascular system, respiratory organs, liver, kidney) |
Danger |
H370 | P308+P311 P260 P264 P270 P321 P405 P501 |
Based on the human evidence: "clinical symptoms include transient hemolytic anemia, nausea, headache, anemia, decreased hemoglobin levels, erythema of the skin, jaundice, hemoglobinuria and shock" (IARC 84 (2004)), "pulmonary edema and acute circulatory disorder," "hepatitis on the 20th day after the acute hemolysis" (CICAD 47 (2002)), "hemolysis and nephropathy" (ACGIH (7th, 2001)), and the evidence from animal studies including "a 10.5% reduction in hematocrit levels observed in the 26ppm dose group" (CICAD 47 (2002)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 1. | FY2006 | GHS Classification Manual (10 Feb, 2006) |
9 | Specific target organ toxicity - Repeated exposure | Category 1 (blood system) |
Danger |
H372 | P260 P264 P270 P314 P501 |
Based on the human evidence including "a decrease in hemoglobin level to 32g/L and basophilic stippling (in red blood cells)" (IARC 84 (2004)), and the evidence from animal studies including "anemia (decreased hemoglobin/hematocrit/RBC)" (CICAD 47 (2002)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 1. |
FY2006 | GHS Classification Manual (10 Feb, 2006) |
10 | Aspiration hazard | Not classified (Not applicable) |
- |
- | - | Not applicable | FY2006 | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Pictogram Signal word |
Hazard statement (code) |
Precautionary statement (code) |
Rationale for the classification | Classification year (FY) | GHS Classification Guidance for the Japanese Government | |
---|---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment Short term (Acute) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
11 | Hazardous to the aquatic environment Long term (Chronic) | Classification not possible |
- |
- | - | No data available | FY2006 | GHS Classification Manual (10 Feb, 2006) |
12 | Hazardous to the ozone layer | - |
- |
- | - | - | - | - |
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