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NITE TOP＞
Chemical Management Field＞
NITE-CHRIP
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NITE-CHRIP is a database provided information on Risk Assessments
and Laws & Regulations, etc., of chemical substances.
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Menu
Click "Total Serch" to "Enter Search Conditions" Page.
Click "Lists" to "Selecting List" Page.
Search; Entering Search Conditions
General Search, Search Options
There are two modes, “General Search” and “Search Options”.
You can switch anytime between two modes by clicking the top tab of the modes.
| General Search : | You can search by Keyword and refine by Category. |
| Search Options : | You can use wild cards in your query terms and search by molecular structure is possible. |
If you enter the query terms in "Search by Number", "Search by Name", "Search by Molecular Formula" or "Search by Structure", the substance that is relevant to all your search terms will be retrieved.
You can confine your search by choosing categoryies of your target substances.
Keyword
Search by number
Enter the number of substance of interest to you and select "CAS RN", "MITI Number", or others from the pull-down menu.
Other than the ISHA Number, search by number is exact match search.
But in "Search Options" mode, you can use a wild card "*" or "?".
"*" Matches any number of characters.
"?" Matches any single character in the specified location.
| Substance Number | Available Punctuations | Examples |
| CAS No. | Half-sized or full-sized number, number with hyphen Number without hyphen, in the case of not using a wild card | CAS No. 50-00-0:50-00-0, 50000 |
| MITI No. | Half-sized or full-sized number, number with hyphen | MITI No. 2-10:2-10 |
| ISHA No. | Half-sized or full-sized number, number with hyphen, "partial match" | ISHA No. 4-(12)-737:4-(12)-737, |
| EC No. | Half-sized or full-sized number, number with hyphen | EC No. 123-456-7:123-456-7 |
| UN No. | Half-sized or full-sized number, 4-digit number | UN No. 0005:0005 | CHRIP_ID | Half-sized or full-sized number, number with hyphen | CHRIP_ID C123-456-78:C123-456-78A | Nikkaji No. | Half-sized or full-sized number, number with hyphen | Nikkaji No. J1.000.000A:J1.000.000A |
Search by name
In "General Search" mode, you can enter several keywords separated by space (1). You can select the name of interest from the pull-down menu (2).
In "Search Options" mode and in the case of not using a wild card, your search will be an exact match. But in the case of using a wild card characters (3), you can enter several keywords separated by space. You can search in the manner of "Include any keywords" or "Not include the keyword". If you enter keywords in more than one input field, you will retrieve the substance name, matching all of those conditions. You can retrieve the name of interest from each pull-down menu (2).
(1) If you select a partial match from the pull-down menu, you retrieve the substance name, including all of several keywords. In the case of an exact match, you retrieve the substance name entirely consistent with the entered keyword including the space.
(2) You can select "All" name, "General" name, "Synonym" or "Each Source", from the pull-down menu.
(3) You can use a wild card "*" or "?".
"*" Matches any number of characters.
"?" Matches any single character in the specified location.
Search by Molecular Formula
Please enter a molecular formula with alphanumeric symbols by Hill method in the input field. In this method, the substance containing carbon is described initially C and H in the following, followed by other elements in alphabetical order. For substances that do not contain carbon, it will describe all of the elements in alphabetical order.
Display Setting
Interim Search Result
You can select the display format of Interim Search Result as indicated below.
| Structure Display Options | Select Yes or No from the pull-down menus to display structures in the Interim Search Result. |
| Display-Number Limit | Select the maximum number of search results displayed in one page from the pull-down menu. |
Search Results
You can select the display format of Search Results. By default, the only items containing some data will be displayed. To display all, including empty items, please click the check "Including blank data.".
Search by Structure
This field allows you to search the NITE-CHRIP database : about 30,000 chemical structures
Input chemical structure search options for the substance of interest to you as indicated.
| SMILES | Enter SMILES of the substance of interest to you. |
| Structure File | Select structure files (MOL (.mol) or SMILES(.smi)) from the pull-down menu. Enter the File Pass into the text box below and click on the load button. The system will display a structural formula based on the input structure file. Use only the extension for the files as specified. |
| Structure Search Method |
Select one among three structure search methods ((Partial Match, Exact Match and Similarity). If you select "Similar", please enter the percentage of structural similarity (percentage of similarity) (%). Tanimoto: Tanimoto Similarity Search |
| Molecular Weight | Enter ranges for molecular weight of the substance |
Search by Category
Check the check box of interest to you in the category tree. If you check the upper item, the lower item will be checked in conjugation with it. If you remove the check of upper item, the lower item also will be removed.
| Item | Operation |
| "-" button | Close the lower items |
| "+" button | Open the lower items |
| "Default" button | Reset all items |
| "Close All" button | Close all items |
| "Open All" button | Open all items |
| "Check All" button | Check the check box of all the items |
| "Uncheck All" button | Uncheck the check box of all the items |
Information sources are as follows.
| Section | Sub section | Information sources | Categories |
| General Information | Nikkaji | Information of Japan Chemical Substance Dictionary (Nikkaji) | |
| Laws and Regulations in Japan | Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. (Chemical Substances Control Law ; CSCL) | Class I Specified Chemical Substances | |
| Class II Specified Chemical Substances | |||
| Monitoring Chemical Substances | |||
| Priority Assessment Chemical Substances | |||
| Newly Announced Chemical Substances (notified on and after April 1, 2011) | Section 1 - Section 9 | ||
| Newly Announced Chemical Substances (notified by March 31, 2011) | Section 1 - Section 9 | ||
| Existing Chemical Substances | Section 1 - Section 9 and The Japanese Pharmacopoeia 8th Edition | ||
| Type II Monitoring Chemical Substances (before amendment) | |||
| Type III Monitoring Chemical Substances (before amendment) | |||
| Chemical Substances exempted from notification of manufacturing/import amount | Section 1 - Section 9 | ||
| Chemical Substances not regarded as a New Chemical Substances | Regarded as a Class I Specified Chemical Substance Regarded as a Class II Specified Chemical Substance Regarded as a Monitoring Chemical Substance Regarded as a Priority Assessment Chemical Substance Not Regarded as a New Chemical Substance | ||
| Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof | Act on Confirmation, etc. of Release Amounts of Specific Chemical Substances in the Environment and Promotion of Improvements to the Management Thereof | I, Specified Class I, II | |
| Industrial Safety and Health Act (ISHA) | Existing Chemical Substances | ||
| Newly Announced Chemical Substances | Chemical Substances prohibited from Manufacturing, etc. | Chemical Substances requiring permission of Manufacture, etc. | Chemical Substances requiring Labeling and Deliver of Documents, etc. | Dangerous Substances | Explosive Substances Combustible Substances Oxidizing Substances Inflammable Substances Combustible gases | Specified Chemical Substances | Group-1,2,3 | Lead, etc. / Tetraalkyl lead, etc | Ordinance on Prevention of Lead Poisoning and Tetraalkyl Lead Poisoning | Organic Solvents | First, Second, Third-class organic solvents, etc. | Administrative Control Levels of Working Environment Evaluation Standards | Strong Mutagenic Chemical Substances | Existing Chemical Substances Notified Chemical Substances |
| Poisonous and Deleterious Substances Control Act | Poisonous and Deleterious Substances Control Act | Poisonous Substances (Law) Specified Poisonous Substances (Law) Deleterious Substances (Law) Poisonous Substances (Cabinet order) Specified Poisonous Substances (Cabinet order) Deleterious Substances (Cabinet order) | |
| Act on the Prohibition of Chemical Weapons and the Control, etc. of Specific Chemicals (Chemical Weapons Prohibition Law) | Act on the Prohibition of Chemical Weapons and the Control, etc. of Specific Chemicals (Chemical Weapons Prohibition Law) | Specific Chemicals (Toxic chemicals),(Precursor) First Class Designated Chemicals (Toxic chemicals),(Precursor) Second Class Designated Chemicals (Toxic chemicals),(Precursor) | |
| Act on the Protection of the Ozone Layer through the Control of Specified Substances and Other Measures | Act on the Protection of the Ozone Layer through the Control of Specified Substances and Other Measures | Phase-in substance(s) subject to registration, A-I, A-II, B-I, B-II, B-III, C-I, C-II, C-III, E-I | |
| Air Pollution Control Law | Air Pollution Control Law | Soot and Smoke Toxic Substances Automobile Exhaust Gases Specific Substances Designated Substances Hazardous Air Pollutants Hazardous Air Pollutants (/Priority Chemicals) VOC Exclusion Substances Designated Particulates | |
| Water Pollution Control Law | Water Pollution Control Law | Harmful SubstancesDesignated Substances | |
| Soil Contamination Countermeasures Act | Soil Contamination Countermeasures Act | Class 1, 2, 3 | |
| Law for the Control of Household Products Containing Harmful Substances | Law for the Control of Household Products Containing Harmful Substances | ||
| Laws and Regulations in Other countries | Recommendations on the transport of dangerous goods | UN Number and UN Hazard Class | 1-9 and - |
| Stockholm Convention on Persistent Organic Pollutants (POPs) | Stockholm Convention on Persistent Organic Pollutants (POPs) | A, B, C and (A,C) | |
| Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (PIC) | Rotterdam Convention on the Prior Informed Consent Procedure for Certain Hazardous Chemicals and Pesticides in International Trade (PIC) | Industrial Pesticide Severely hazardous pesticide formulation | |
| Association of South-East Asian Nations(ASEAN) | The ASEAN-Japan Chemical Safety Database (AJCSD): Laws and Regulations | ||
| European Union (EU) | EC Inventory | ||
| REACH: Substances of Very High Concern for Authorization (SVHC) | Authorisation List Candidate List | ||
| EU: CLP Harmonised Classification | |||
| US: Toxic Substances Control Act (TSCA) | TSCA Inventory | ||
| Significant New Use Rule (SNUR) | |||
| Regulation of hazardous chemical substances and mixtures | |||
| China | China: Catalog of Hazardous Chemicals 2015 | ||
| Korea:Act on the Registration and Evaluation, etc. of Chemical Substances (ARECs / K-REACH) / Chemicals Control Act (CCA) | Korea: ARECs (K-REACH) / CCA; Hazardous Substance(s), Priority Control Substances | Toxic Substance(s) Restricted Substance(s) Prohibited Substance(s) Accident Precaution Chemical Priority Control Substances | |
| Korea: ARECs (K-REACH); Existing Chemical Substances | Existing Chemical Substances (Domestically distributed commercial purpose before 2 February, 1991.) Existing Chemical Substances (Has undergone hazard review after 2 February, 1991.) | ||
| Korea: ARECs (K-REACH); Others | Phase-in substance(s) subject to registration (by June 30, 2018) CMR Substances (shall be registered by December 31, 2021) Chemical Substances Exempted from Registration or Notification | ||
| Chemical Hazard and Risk Information | GHS Classification Results | GHS Classification Results by the Japanese Government | 2006-2016 |
| AJCSD: GHS Classification Results / Sample SDS | |||
| Hazard and Risk Assessment Reports etc. in Japan | Chemical Substances Hazard Assessment Report / Initial Risk Assessment Report | ||
| Hazard Data Sheet for Chemical Substances | |||
| CSCL: The Japan HPV Challenge Program | |||
| Hazard and Risk Assessment Reports etc. in Other Countries | OECD: High Production Volume (HPV) Chemicals | ||
| International Chemical Safety Cards (ICSC | |||
| Concise International Chemical Assessment Documents (CICADs) | |||
| Environmental Health Criteria (EHC) | |||
| US Agency for Toxic Substances and Disease Registry (ATSDR): Toxicological Profiles | |||
| US EPA: Integrated Risk Information System (IRIS) | |||
| EU: Risk Assessment Reports (RAR) | |||
| Advisory Committee on Existing Chemicals (BUA) Reports by the German Chemical Society | |||
| Canada: Priority Substances List (PSL) | PSL1, PSL2 | ||
| Australia: Priority Existing Chemicals (PEC) Assessment Reports | |||
| Japan Society for Occupational Health (JSOH) | Occupational Exposure Limits | ||
| Occupational Exposure Limits Based on Biological Monitoring | |||
| Occupational Carcinogens | 1, 2A, 2B | ||
| Occupational Sensitizers | Airway Group 1 Airway Group 2 Skin Group 1 Skin Group 2 Skin Group 3 Airway Group 1/Skin Group 1 Airway Group 1/Skin Group 2 Airway Group 2/Skin Group 1 Airway Group 2/Skin Group 2 | ||
| Reproductive Toxicants | 1, 2, 3 | ||
| Carcinogenicity Assessment | IARC: Carcinogenicity Assessment | 1, 2A, 2B, 3, 4 | |
| US EPA: Carcinogenicity Assessment | 1986 : A - 2005 : NL | ||
| US NTP: Carcinogenicity Assessment | k, R | ||
| EU: Carcinogenicity Assessment | 1A, 1B, 2 | ||
| ICCA Safety Summary of Japan(JCIA BIGDr) | ICCA Safety Summary of Japan(JCIA BIGDr) | ||
| Test Data and Reports | Japan METI: Biodegradation and Bioconcentration Results | ||
| Japan MHLW: Toxicity Test Results | |||
| Japan MOE: Results of Eco-toxicity tests of chemicals | |||
| ISHA: Mutagenicity Test Results for Chemical Substances | |||
| Japan METI: Safety Test | Combined Repeated Dose Toxicity Study with the Reproduction/Developmental Toxicity Screening Test (OECD TG422) Acute Oral Toxicity - Acute Toxic Class Method (OECD TG423) Bacterial Reverse Mutation Test (OECD TG471) In Vitro Mammalian Chromosome Aberration Test (OECD TG473) | ||
| NITE: Toxicity and Eco-toxicity Test Results | |||
| US National Toxicology Program (NTP) : Long-Term Study Reports & Abstracts |
Interim Search Results; Interim Search Results (Display by CHRIP ID and CAS RN)/List Stage Two (Display by CHRIP ID and CAS RN)
Search Results
If more than one CHRIP_ID that corresponds to the search condition are retrieved, the list of the concerned substances will be displayed. You can sort the list of the search results and transition to "Search Results" page.
Chemical substances displaying (※1)(※2)(※3) at the Interim Search Results(Display by CHRIP ID and CAS RN) means as follws.
(※1) The substance which matches the substance indicated by MITI number or cabinet order number when a certain condition is fulfilled. The condition is listed in the remarks column of the search result, so be sure to check it.
(※2) The substance which is regarded as CSCL: Class I Specified Chemical Substances, Class II Specified Chemical Substances, Monitoring Chemical Substances, Priority Assessment Chemical Substances by the operation notification "Implementation of the Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. 3-2(1)".
(※3) The substance which had been designated in accordance with paragraph (5) of Article 2 of the CSCL: Priority Assessment Chemical Substances and later was cancelled.
Chemical substances displaying (※1)(※2)(※3) at the Interim Search Results(Display by CHRIP ID and CAS RN) means as follws.
(※1) The substance which matches the substance indicated by MITI number or cabinet order number when a certain condition is fulfilled. The condition is listed in the remarks column of the search result, so be sure to check it.
(※2) The substance which is regarded as CSCL: Class I Specified Chemical Substances, Class II Specified Chemical Substances, Monitoring Chemical Substances, Priority Assessment Chemical Substances by the operation notification "Implementation of the Act on the Evaluation of Chemical Substances and Regulation of Their Manufacture, etc. 3-2(1)".
(※3) The substance which had been designated in accordance with paragraph (5) of Article 2 of the CSCL: Priority Assessment Chemical Substances and later was cancelled.
| Item | Operation |
| "No." link | Transition to "Search Results" page |
| "▲"、"▼" sort button | The target items are sorted in ascending order by clicking the "▲" button and in descending order by clicking the "▼" . |
In the list of interim search results, you can switch the display that noted in the table below.
| Item | Operation |
| "<<Previous Page" link | Display the previous page |
| "n-m" pull-down menu | Display the optional page |
| "Next Page>>" link | Display the next page |
| "Results / page" pull-down menu | Switch the number of display in one page |
"Interim Search Results (Display by Decree number etc)" link
When the information source is refined to only one by "Search by Category" in "Entering Search Conditions" display, "Interim Search Results (Decree number etc based)" link is displayed. By clicking this link, "Interim Search Results (Decree number etc based)" will be displayed.
"Display by Decree number etc" link
By clicking "Display by Decree number etc" link in "Display by CHRIP ID and CAS RN" page, you can transition to "Display by Decree number etc" page.
"Downloading the search results" link
If you click "Downloading the search results" link, the list of search results in TSV format (tab separated values format) will be downloaded.
"Add other laws and regulations etc" button
If you click "Add other laws and regulations etc" button, the screen will transition to <Add list items> display. If you check the items that you would like to add in <Add list items> display and click "Redisplay" button, the screen will transitions to "Interim Search Results (Display by CHRIP ID and CAS RN)" screen. Items that can be added are up to 10.
If you would like to delete the added items, please click "Add list items" button again and remove the check in <Add list items> screen and click "Redisplay" button.
Re-search Condition Input
"Interim Search Results (Display by CHRIP ID and CAS RN)" screen has the same function as "Enter Search Conditions" screen on the upper of the screen. You can perform additional query by adding more search parameters or changing terms.
Selecting List
Category
Selecting the source of information in "Source of Information" tree allows you to transition to "Interim Search Results (Display by Decree number etc )" screen or open another screen of "Data Description". You can open or close the tree items.
| Item | Operation |
| "-" button | Close the lower items |
| "+" button | Open the lower items Display the optional page |
| "Source of Information" link | Transition to "Display by Decree number etc" page |
| "Data Description" link | Display the description of the search result on another page |
List; Display by Decree number etc
List of information that corresponds to the source of information selected in "Selecting List" page is displayed. You can sort the list of information displayed and transition to "Display by CHRIP ID and CAS RN" screen or "Search Results" page.
| Item | Operation |
"  "Link button |
Transition to "Search Results" page in the case that there is one CHRIP_ID for corresponding information. Transition to Display by CHRIP ID and CAS RN screen in the case that there are more than one CHRIP_ID for corresponding information. |
| "▲"、"▼" sort button | The target items are sorted in ascending order by clicking the "▲" link and in descending order by clicking the "▼" . |
Data Description
Clicking the link allows you to display the description about the source of information on another page.
Information displayed.
You can switch the list of information displayed.
| Item | Operation |
| "Category" pull-down menu | Display the information corresponds to the selected category |
| "<<Previous Page" link | Display the previous page |
| "n-m" pull-down menu | Display the optional page |
| "Next Page>>" link | "Display the next page |
| "Results / page" pull-down menu | Switch the number of display in one page |
Downloading the search results
If you click "Downloading the search results" link, the list of search results in TSV format (tab separated values format) will be downloaded.
List Stage Two (CHRIP_ID based)
You can transition to "List Stage Two (CHRIP_ID based)" screen that displays a set of CHRIP_ID, CAS No. and Chemical Substance Name.