Chemical Name:Ethanol, 2-(diethylamino)-
CAS:100-37-8
ID: | 124 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Liquid (GHS definition) |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid (GHS definition) |
5 | Gases under pressure | Not applicable | - | - | - | - | Liquid (GHS definition) |
6 | Flammable liquids | Category 3 | Warning | H226: Flammable liquid and vapour |
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
Flash point: 52degC, Boiling point: 163degC | |
7 | Flammable solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
9 | Pyrophoric liquids | Not classified | - | - | - | - | The ignition points is 250 degC and it is thought that in room temperatures it does not ignite. |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Organic compounds containing oxygen (but not chlorine and fluorine) chemically bonded only to carbon and hydrogen (but not to other elements). |
14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no -0-0- structure |
16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available on corrosion to metals |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 4 | Warning | H302: Harmful if swallowed |
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ... |
SPECIES: Rat ENDPOINT: LD50 VALUE: 1320 mg/kg REFERENCE SOURCE: SIDS(2003) | |
1 | Acute toxicity (Dermal) | Category 4 | Warning | H312: Harmful in contact with skin |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P280: Wear protective gloves/protective clothing/eye protection/face protection. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P322: Specific treatment (see ... on this label). P363: Wash contaminated clothing before reuse. P501: Dispose of contents/container to ... |
It was set as Category 4 with the value of rabbit LD50= 1ml/kg (reduced value: 890mg/kg) (ACGIH (2001)). | |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Liquid (GHS definition) |
1 | Acute toxicity (Inhalation: Vapours) | Category 3 | Danger | H331: Toxic if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P311: Call a POISON CENTER or doctor/physician. P321: Specific treatment (see ... on this label). P405: Store locked up. P501: Dispose of contents/container to ... |
Rat Inhalation LC50: 4600mg/m3 (equivalent of 960ppm) (SIDS (2003)), 4500mg/m3 (equivalent of 940 ppm) (ACGIH (2001)), and 945ml/m3 (equivalent of 945ppm) (DFGOT vol.14 (2000)). Since the saturated vapor pressure concentration at 20degC is less than 1777ppm, they are considered to be inhalation steam tests. Therefore, it was classified as Category 3. | |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | No data available |
2 | Skin corrosion/irritation | Category 1C | Danger | H314: Causes severe skin burns and eye damage |
P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P321: Specific treatment (see ... on this label). P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ... |
Since corrosivityity is verified in an examination (4 hours) on rabbits under OECD guideline 404 (SIDS (2003)), it was classified as Category 1C. | |
3 | Serious eye damage/eye irritation | Category 1 | Danger | H318: Causes serious eye damage |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. |
Since there is the conclusion data of "critical damage over an eye" (CERI Hazard Data (2001)) and it was set to Category 1C on the skin, it was set as Category 1. | |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | Respiratory sensitization is uncategorizable because of no information. |
4 | Skin sensitization | Classification not possible | - | - | - | - | Uncategorizable because there are data that indicate sensitization in guinea pig skin(CERI Hazard Data (2001)) and that find no sensitization in guinea pigs (SIDS (2003)) |
5 | Germ cell mutagenicity | Not classified | - | - | - | - | The substance was regarded as outside the categories because there is a negative result in the in vivo mouse micronucleus test (SIDS (2003)). |
6 | Carcinogenicity | Classification not possible | - | - | - | - | There was information (SIDS (2003)) that it was not carcinogenicity (SIDS (2003)). But there was no information of evaluation organizations, so it was determined that it cannot be classified. |
7 | Reproductive toxicity | Not classified | - | - | - | - | Since there was no bad effect to genitalia in rat inhalation test 365mg/m3(14week) (SIDS (2003)), there was no development disorder in 486 mg/m3 inhalation administration to pregnancy rat (SIDS (2003)), and there was no effect to teratogenesis, embryo toxicity, and ferotoxity in inhalation toxicity of rat(DFGOT vol.14(2000)), they were considered as on the outside of Categry according to these information. |
8 | Specific target organ toxicity - Single exposure | Category 1 (systemic toxicity) | Danger | H370: Causes damage to organs (systemic toxicity) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment (see ... on this label). P405: Store locked up. P501: Dispose of contents/container to ... |
It was classified into Category 1 (whole body) since "nausea and vomiting" are observed in human cases (DFGOT vol.14 (2000), SIDS (2003), ACGIH (2001)). | |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (liver) | Warning | H373: May cause damage to organs through prolonged or repeated exposure (liver) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
It was classified into Category 2 since liver disease was observed in rat with 100mg/kg diet (ACGIH (2001)). | |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available on chemical pneumonia |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Category 3 | - | - | H402: Harmful to aquatic life |
P273: Avoid release to the environment. P501: Dispose of contents/container to ... |
It was classified into Category 3 from 72-hour ErC50=44mg/L of algae (Scenedesmus) (SIDS, 2004). |
11 | Hazardous to the aquatic environment (Long-term) | Not classified | - | - | - | - | Since rapidly degrading (22-day decomposition rate of the OECD test guideline 301A: 95% (SIDS, 2002)), and less bio-accumulative (BCF<6.1 (Existing Chemicals Safety Check Data)). |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |