GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：Methane, dichlorodifluoro-
CAS：75-71-8
Result：
| ID: | 131 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | Gas (GHS definition) |
| 2 | Flammable gases （including chemically unstable gases） | Not classified | - | - | - | - | UNRTDG Class: 2.2 |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Not classified in UNRTDG Subsidiary risks Class: 5.1 |
| 5 | Gases under pressure | Low pressure liquefied gas |
|
Warning | H280: Contains gas under pressure; may explode if heated | P410+P403: Protect from sunlight. Store in a well-ventilated place. | Low pressure liquefied gas because of the critical temp: >65degC. |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 7 | Flammable solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 11 | Self-heating substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Gas (GHS definition) |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Gas (GHS definition) |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to gas substances are not available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Classification not possible | - | - | - | - | Although there is information that 1000mg/kg or more is lethal in rats (EHC113(1990), CERI Hazard Data (1998)), it cannot be classified since it cannot know whether it exceeds 2000mg/kg of Category 4 or not. |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Gases） | Not classified | - | - | - | - | The value of LC50: >800000ppm/0.5h (4 hour reduced values: >282842ppm) (CERI Hazard Data (1998)) in rat inhalation exposure exceeds. The value exceeding 12500ppm (gas 5000ppm(4) *2.5), it was considered as the outside of Category. |
| 1 | Acute toxicity （Inhalation: Vapours） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 2 | Skin corrosion/irritation | Not classified | - | - | - | - | Based on the information that it "has a slight irritation" (CERI Hazard Data (1998), EHC 113 (1990)) and "was unirritating" (DFGOT 5th (1993)), it was classified as out of Category. |
| 3 | Serious eye damage/eye irritation | Not classified | - | - | - | - | Since there are information that it has recovered at the next day although there was minimal deficit with a rabbit (CERI Hazard Data (1998)), and that stimulation was not seen with a rabbit (ACGIH (2001)), it was carried out the outside of Category. |
| 4 | Respiratory sensitization | Not classified | - | - | - | - | Respiratory sensitization was classified as out of category because animal testing shows no abnormalities (DFGOT 5th (1993)). |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | Skin sensitization is uncategorizable because of insufficient data although it is suggested in the effect to humans (CERI Hazard Data (1998)). |
| 5 | Germ cell mutagenicity | Not classified | - | - | - | - | The substance was regarded as outside the categories because the results of the in vivo dominant lethal tests in rats are negative (EHC 113 (1990), CERI Hazard Data (1998)). |
| 6 | Carcinogenicity | Not classified | - | - | - | - | It is A4 in ACGIH which is a classification organization, and there were reports that a carcinogenic evidence cannot be found in animal experiments (EHC 113 (1990), DFGOT, 5th (1993)) And also that increase of and cancer incidences was not observed (CERI Hazard Data (1998)). So it was set as the outside of Category. |
| 7 | Reproductive toxicity | Not classified | - | - | - | - | According to the test result that "there was no abnormality of pregnancy rate, birth rate, and survival rate of new born in three generation test"of rat, and according to the test result that "there were no ferotoxity and teratogenicity", "there were no ferotoxity, teratogenicity, and there was no toxicity in new born" of rat and rabbit (CERI Hazard Data (1990), EHC 113 (1990), DFGOT 5th (1993)), and they were considered as on the outside of Categry |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | Although conrtraction, tremor, absent reflex, and loss of the corneal reflex were observed in the rat, it recovered after the end of exposure. Every value was beyond the guidance value by far. Although effects on whole body are indicated at high concentrations in humans, they are mixed in some literatures (CERI Hazard Data (1998), DFGOT 5th, (1993), PATTY (5th, 2005), EHS113 (1990)). And a specific effect cannot be mentioned. Therefore, it cannot be classified. |
| 9 | Specific target organ toxicity - Repeated exposure | Category 1 (nervous system) |
|
Danger | H372: Cause damage to organs through prolonged or repeated exposure (nervous system) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
It was classified into Category 1 since nervous system damage was observed to the human by occupational exposure (CERI Hazard Data (1998)). |
| 10 | Aspiration hazard | Not applicable | - | - | - | - | Gas (GHS definition) |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | Insufficient data available. |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |