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GHS Classification Result

Chemical Name：2-bromopropane
CAS：75-26-3

Result：


ID:	187
Classifier:	Inter-ministerial Committee on GHS
Year Classified:	FY2006
Reference Manual:	GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	There are no chemical groups associated with explosive properties present in the molecules.
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products
4	Oxidizing gases	Not applicable	-	-	-	-	Liquid (GHS definition)
5	Gases under pressure	Not applicable	-	-	-	-	Liquid (GHS definition)
6	Flammable liquids	Category 2		Danger	H225: Highly flammable liquid and vapour	P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ...	Flash point: <23degC, Initial boiling point: >35degC
7	Flammable solids	Not applicable	-	-	-	-	Liquid (GHS definition)
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9	Pyrophoric liquids	Not classified	-	-	-	-	UNRTDG Class: 3
10	Pyrophoric solids	Not applicable	-	-	-	-	Liquid (GHS definition)
11	Self-heating substances and mixtures	Not classified	-	-	-	-	UNRTDG Class: 3
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13	Oxidizing liquids	Not applicable	-	-	-	-	Organic compounds containing no oxygen, fluorine and chlorine.
14	Oxidizing solids	Not applicable	-	-	-	-	Liquid (GHS definition)
15	Organic peroxides	Not applicable	-	-	-	-	Containing no -0-0- structure
16	Corrosive to metals	Classification not possible	-	-	-	-	No data available

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Classification not possible	-	-	-	-	No data available
1	Acute toxicity （Dermal）	Classification not possible	-	-	-	-	No data available
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
1	Acute toxicity （Inhalation: Vapours）	Not classified	-	-	-	-	Based on Mouse LC50 (4 hours) value: 31171ppm (equivalent of 156.48mg/L), it was classified as out of Category.
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	No data available
2	Skin corrosion/irritation	Category 3	-	Warning	H316: Causes mild skin irritation	P332+P313: If skin irritation occurs: Get medical advice/attention.	Since change which is equivalent to basis of mild irritation in the test on rabbits indicated to ECETOC TR 66 (1992) was observed, it was classified as Category 3.
3	Serious eye damage/eye irritation	Classification not possible	-	-	-	-	No data available
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available
4	Skin sensitization	Classification not possible	-	-	-	-	No data available
5	Germ cell mutagenicity	Not classified	-	-	-	-	The substance was regarded as outside the categories because there are negative results from the micronucleus tests using mouse erythrocytes, which are in vivo mutagenicity tests using somatic cells (CERI Hazard Data, 2002, Japan Society for Occupational Health Recommendations, 1999, MOE Risk Assessment Vol. 4, 2005).
6	Carcinogenicity	Classification not possible	-	-	-	-	No data available
7	Reproductive toxicity	Category 1A		Danger	H360: May damage fertility or the unborn child	P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ...	There is the description that there are the obvious effect to generative organ such as the reduction of the number of spermatozoid and the cessation of menses in the human exposure example (CERI Hazard Data (2002), MOE Risk Assessment of the 4th volume (2005) and industrial hygene academic recommendation (1999)). So it was considered as in the Category 1A.
8	Specific target organ toxicity - Single exposure	Classification not possible	-	-	-	-	Although in the 4th volume of MOE Risk Assessment (2005) there was a description that the toxic effects is not observed at higher exposure level to mouse, there is no other data and it is in sufficient data for the outer Category. Therefore, it cannot be classified.
9	Specific target organ toxicity - Repeated exposure	Category 1 (testis, ovaria, blood)		Danger	H372: Cause damage to organs through prolonged or repeated exposure (testis, ovaria, blood)	P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ...	In exposure example to human in CERI Hazard Data (2002), MOE Risk Assessment the 4th volume (2005) , and industrial hygene academic society advice (1999), due to the description that low sperm count, missed period, and anemia were observed, it was classified into Category 1 (testes, ovary, blood).
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Category 3	-	-	H402: Harmful to aquatic life	P273: Avoid release to the environment. P501: Dispose of contents/container to ...	It was classified into Category 3 from 48-hour EC50=23mg/L of Crustacea (Daphnia magna) (MOE eco-toxicity tests of chemicals, 2000).
11	Hazardous to the aquatic environment （Long-term）	Not classified	-	-	-	-	Since rapidly degrading (BOD: 83% (existing chemical safety inspections data)), and less bio-accumulative (log Kow=2.14 (PHYSPROP Database, 2005)).

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model SDS by MHLW	MHLW Website （in Japanese Only）