GHS Classification Result

Chemical Name:Disodium tetraborate, anhydrous
CAS:1330-43-4

Result:
ID: 197
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Containing no chemical groups with explosive properties
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Classified as "solid" according to GHS definition
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Classified as "solid" according to GHS definition
5 Gases under pressure Not applicable - - - - Classified as "solid" according to GHS definition
6 Flammable liquids Not applicable - - - - Classified as "solid" according to GHS definition
7 Flammable solids Not classified - - - - Non-flammable (ICSC, 1999)
8 Self-reactive substances and mixtures Not applicable - - - - Containing no chemical groups with explosive or self-reactive properties
9 Pyrophoric liquids Not applicable - - - - Classified as "solid" according to GHS definition
10 Pyrophoric solids Not classified - - - - Non-combustible (ICSC, 1999)
11 Self-heating substances and mixtures Not classified - - - - Non-combustible (ICSC, 1999)
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water (water solubility: 2.56g/100mL (20degC), ICSC (1999))
13 Oxidizing liquids Not applicable - - - - Classified as "solid" according to GHS definition
14 Oxidizing solids Classification not possible - - - - Classification not possible due to lack of data, though inorganic compounds containing oxygen
15 Organic peroxides Not applicable - - - - Not organic compounds
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ...
Based on the rat LD50 (oral route) value of 1,200mg/kg representing the lower of the two testing data, 1,200mg/kg (RTECS (2005)) and 2,660mg/kg (HSDB (2005)).
1 Acute toxicity (Dermal) Classification not possible - - - - Insufficient data available
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Due to the fact that the substance is "solid" according to the GHS definition and inhalation of its gas is not expected.
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - Insufficient data available
2 Skin corrosion/irritation Classification not possible - - - - No data available. As for the health hazards, refer to "ID:0198, CAS No:1303-96-4, Sodium Tetraborate (10 hydrate)."
3 Serious eye damage/eye irritation Category 2A-2B Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
Based on the description of the human health effects (ECETOC TR63 (1995)): "Sodium tetraborate, in the form of dust, causes eye irritation," though the severity of the effects are not presented. The substance should be placed in Category 2A from the viewpoint of safety if further subclassification is needed.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - No data available. As for the health hazards, refer to "ID:0198, CAS No:1303-96-4, Sodium Tetraborate (10 hydrate)."
5 Germ cell mutagenicity Classification not possible - - - - No data available As for the health hazards, refer to "ID198, Sodium Tetraborate (10 hydrate), CAS: 1303-96-4" and "ID491, Boric Acid, CAS: 10043-35-3."
6 Carcinogenicity Not classified - - - - Due to the fact that the substance is classified as Category A4 (borates compounds, inorganic [1330-43-4; 1303-96-4; 10043-35-3; 12179-04-3]) by ACGIH (2005).
7 Reproductive toxicity Classification not possible - - - - No data available As for the health hazards, refer to "ID198, Sodium Tetraborate (10 hydrate), CAS: 1303-96-4" and "ID491, Boric Acid, CAS: 10043-35-3."
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available * As "inorganic borate exists as boric acid in a diluted aqueous solution of physiological pH," (PATTY (4th, 2000)), refer to "Sodium Tetraborate (10 hydrate) (ID: 0198)" and "Boric Acid (ID: 0491)."
9 Specific target organ toxicity - Repeated exposure Category 1 (respiratory system) Danger H372: Cause damage to organs through prolonged or repeated exposure (respiratory system) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ...
Based on the human evidence including "nasal/eye/pharyngeal irritation, coughing and short of breath" (EHC 204 (1998)). * As "inorganic borate exists as boric acid in a diluted aqueous solution of physiological pH," (PATTY (4th, 2000)), refer to "Sodium Tetraborate (10 hydrate) (ID: 0198)" and "Boric Acid (ID: 0491)."
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Not classified - - - - It was classified into Not classified from 96-hour LC50=74mg boron/L (Sodium Tetraborate Equivalent: 1378mg/L) of the fish (Pleuronectes Yokohamae Gunther) (EHC204, 1998).
11 Hazardous to the aquatic environment (Long-term) Not classified - - - - Since it was not water-insolubility (the water-solubility =25000mg/L (HSDB, 2004)), and acute toxicity was low, it was classified into Not classified.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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