GHS Classification Result

Chemical Name：Cadmium sulphide
CAS：1306-23-6

Result：
ID: 252
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Containing no chemical groups with explosive properties
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Classified as "solid" according to GHS definition
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Classified as "solid" according to GHS definition
5 Gases under pressure Not applicable - - - - Classified as "solid" according to GHS definition
6 Flammable liquids Not applicable - - - - Classified as "solid" according to GHS definition
7 Flammable solids Classification not possible - - - - Classification not possible due to lack of data, though classified as "flammable" by ICSC (1999).
8 Self-reactive substances and mixtures Not applicable - - - - Containing no chemical groups with explosive or self-reactive properties
9 Pyrophoric liquids Not applicable - - - - Classified as "solid" according to GHS definition
10 Pyrophoric solids Classification not possible - - - - No data available
11 Self-heating substances and mixtures Classification not possible - - - - No data available
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water; insoluble (ICSC, 1999)
13 Oxidizing liquids Not applicable - - - - Classified as "solid" according to GHS definition
14 Oxidizing solids Not applicable - - - - Inorganic compounds containing no oxygen and halogen
15 Organic peroxides Not applicable - - - - Not organic compounds
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ... 		From two testing data, rat LD50 (oral route) value of >5,000mg/kg (CaPSAR (1994)) and mouse LD50 (oral route) value of 1,166mg/kg (EHC 134 (1992)), mouse LD50 value, which is the fixed value, was adopted.
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Due to the fact that the substance is "solid" according to the GHS definition and inhalation of its gas is not expected.
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 2 Warning H315: Causes skin irritation P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P362: Take off contaminated clothing and wash before reuse. 		Based on the description in HSDB (2005) of the human health effects: direct contact (as solution) may produce erythema and pain. The substance is thus considered "irritating" to the skin, although should be placed in Category 2 from the viewpoint of safety.
3 Serious eye damage/eye irritation Category 2A-2B Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection. 		Based on the description in HSDB (2005) of the human health effects: Painful conjunctivitis, photophobia, lacrimation, & amp; corneal opacity. The substance is thus considered "irritating" to the eyes, although should be placed in Category 2A from the viewpoint of safety, if further subclassification is needed.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - No data available
5 Germ cell mutagenicity Classification not possible - - - - Based on the absence of data on multi-generation mutagenicity tests, germ cell/somatic cell mutagenicity tests in vivo and germ cell/somatic cell genotoxicity tests in vivo, no strong positive data on mutatogenicity tests in vitro, described in IARC 58 (1993). As for health hazards, refer to "ID254, Cadmium Chloride, CAS: 10108-64-2."
6 Carcinogenicity Category 1A Danger H350: May cause cancer P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Due to the fact that the substance is classified as Category K (as cadmium and cadmium compounds) by NTP (2005), Group 1 (as cadmium and cadmium compounds) by IARC (1993) and Category 1 (as cadmium and cadmium compounds) by the Japan Society for Occupational Health.
7 Reproductive toxicity Classification not possible - - - - No data available
8 Specific target organ toxicity - Single exposure Category 2 (testis) Warning H371: May cause damage to organs (testis) P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Based on the evidence from animal studies including "an edematous testis associated with microvascular congestion" (HSDB (1999)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 2. And based on the human evidence including "acute toxicity following inhalation (chemical pneumonia, pulmonary edema) and ingestion (acute/severe nausea, vomiting, gastralgia)" (EHC 134 (1992)) (cadmium compounds).
9 Specific target organ toxicity - Repeated exposure Category 1 (kidney, respiratory system) Danger H372: Cause damage to organs through prolonged or repeated exposure (kidney, respiratory system) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ... 		Based on the human evidence including "a significant decrease in the urinary beta2-microglobulin levels of workers due to improvements in the working environment" (EHC 134 (1992)), and the evidence from animal studies including "formation of dose-dependent hyperplastic lesions in the respiratory tract" (CEPA (1994)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 1. The chronic toxicity of cadmium compounds includes "renal failure, pulmonary emphysema" (EHC 134 (1992)), "hypercalcinuria, a decrease in blood phosphate levels, nephrolithiasis, osteoporosis, osteomalacia" (CaPSAR (1994)).
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Category 1 Warning H400: Very toxic to aquatic life P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ... 		It was classified into Category 1 from 48 hours LC50=11microg/L of the crustacea (Daphnia magna) (AQUIRE, 2003).
11 Hazardous to the aquatic environment （Long-term） Category 1 Warning H410: Very toxic to aquatic life with long lasting effects P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ... 		Since acute toxicity was Category 1 and it was a metallic compound, and since an underwater action and bio-accumulation were unknown, it was classified into Category 1.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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