GHS Classification Result

Chemical Name：Zinc chromate
CAS：13530-65-9

Result：
ID: 265
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Containing no chemical groups with explosive properties
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Classified as "solid" according to GHS definition
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Classified as "solid" according to GHS definition
5 Gases under pressure Not applicable - - - - Classified as "solid" according to GHS definition
6 Flammable liquids Not applicable - - - - Classified as "solid" according to GHS definition
7 Flammable solids Not classified - - - - Non-flammable (ICSC, 2002)
8 Self-reactive substances and mixtures Not applicable - - - - Containing no chemical groups with explosive or self-reactive properties
9 Pyrophoric liquids Not applicable - - - - Classified as "solid" according to GHS definition
10 Pyrophoric solids Not classified - - - - Non-combustible (ICSC, 2002)
11 Self-heating substances and mixtures Not classified - - - - Non-combustible (ICSC, 2002)
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water; insoluble, ICSC (2002)
13 Oxidizing liquids Not applicable - - - - Classified as "solid" according to GHS definition
14 Oxidizing solids Classification not possible - - - - Classification not possible due to the absence of data, though being inorganic compounds containing oxygen
15 Organic peroxides Not applicable - - - - Not organic compounds
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - No data available
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Due to the fact that the substance is "solid" according to the GHS definition and inhalation of its gas is not expected.
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available
2 Skin corrosion/irritation Classification not possible - - - - Insufficient data available Based on the description in ACGIH (7th, 2001), ATSDR (2000), CERI Hazard Data 97-18 (1998), EHC 61 (1988) and EU-RAR No.53 (2005): Substances including zinc chromate may cause chromium ulcers and skin ulcers (chromium holes) in humans.
3 Serious eye damage/eye irritation Classification not possible - - - - Insufficient data available Based on the description in EU-RAR No.53 (2005) of the effects on human health: Accidental splashing of highly water-soluble Cr(VI) compounds in solution into the eye has resulted in damage to the human eye; A number of case reports indicate corneal/conjunctival inflammation and severe symptoms such as corneal erosion and ulceration, with the intensity of the symptoms increasing at lower pH and higher temperatures; Accidental exposure causes corneal edema and opacity; Single and repeated exposure causes severe, persistent damage to the eye and skin associated with the formation of ulcers.
4 Respiratory sensitization Category 1 Danger H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled P304+P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing.
P342+P311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P285: In case of inadequate ventilation wear respiratory protection.
P501: Dispose of contents/container to ... 		Chromium is classified into "Respiratory Sensitizing Substance" by the ad hoc committee of the Japanese Society of Occupational Allergy, and "Respiratory Sensitizing Substance: Group 2"* by the Japan Society for Occupational Health. These classifications, though not specifying potassium dichromate, seem to include chromium compounds. Potassium dichromate, which is a chromium compound, should thus cause respiratory sensitization. * There is a provision to the effect that "the category refers to the substance concerned and its compounds, but does not identify all substances causing respiratory/skin sensitization.
4 Skin sensitization Category 1 Warning H317: May cause an allergic skin reaction P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P333+P313: If skin irritation or rash occurs: Get medical advice/attention.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P363: Wash contaminated clothing before reuse.
P501: Dispose of contents/container to ... 		Based on the description of human health effects of occupational exposure provided by DFGOT vol.15 (2001): "contact dermatitis (skin sensitization: positive)" have been observed in workers who have handled zinc chromate, suggesting that the substance may cause skin sensitization. Chromium is classified into "Skin Sensitizing Substance" by the ad hoc committee of the Japanese Society of Occupational Allergy, and "Skin Sensitizing Substance: Group 1"* by the Japan Society for Occupational Health. These classifications, though not specifying potassium dichromate, seem to include chromium compounds. Potassium dichromate, which is a chromium compound, should thus cause skin sensitization. * There is a provision to the effect that "the category refers to the substance concerned and its compounds, but does not identify all substances causing respiratory/skin sensitization.
5 Germ cell mutagenicity Classification not possible - - - - Based on the absence of data on in vivo mutagenicity/genotoxicity tests, and the absence of strong positive data on mutagenicity tests in vitro, described in IARC 49 (1990). As for the germ cell mutagenicity of chromium (VI), refer to potassium dichromate (CAS: 7778-50-9).
6 Carcinogenicity Category 1A Danger H350: May cause cancer P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Due to the fact that the substance is classified as Category K (as Chromium hexavalent (VI) compounds) by NTP (2005), A1 by ACGIH (2001), Group 1 (as Chromium (VI)) by IARC (1990), Category 1 (as Chromium hexavalent (VI) compounds) by the Japan Society for Occupational Health.
7 Reproductive toxicity Classification not possible - - - - No data available As for the reproductive toxicity of chromium (VI), refer to potassium dichromate (CAS: 7778-50-9).
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available The acute toxicity of hexavalent chromium compounds manifests as "cough, yellow-green phlegm, dyspnea, pulmonary congestion, vomiting (yellow-green mucus), gastralgia, diarrhea, nausea, vomiting, hepatic damage, renal damage" (CERI Hazard Data 97-18 (1998)). Refer to the GHS classification result of potassium dichromate (ID 0262, CAS 7778-50-09).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available The chronic toxicity of hexavalent chromium compounds manifests as "nasal mucosa, inflammation and ulcers in the pharynx and larynx, nasal septum perforation" (CERI Hazard Data 97-18 (1998)). Refer to the GHS classification result of potassium dichromate (ID 0262, CAS 7778-50-09).
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - No data available
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - No data available


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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