GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：2-Chloro-1-(2,4-dichlorophenyl)vinyl diethyl phosphate; Chlorfenvinphos; CVP
CAS：470-90-6
Result：
| ID: | 322 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | Containing no chemical groups with explosive properties |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
| 6 | Flammable liquids | Not classified | - | - | - | - | Classified as non-flammable (HSDB (2006)) |
| 7 | Flammable solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
| 8 | Self-reactive substances and mixtures | Not classified | - | - | - | - | No data available, though containing unsaturated bonds (olefin). Classified into Division 6.1 (UN#3018 Organophosphorous Pesticide, liquid, toxic (ICSC, 2004) (UN Recommendation on the Transport of Dangerous Goods). |
| 9 | Pyrophoric liquids | Not classified | - | - | - | - | Although classified as flammable, the substance does not catch fire easily (HSDB, 2006). Classified into Division 6.1 (UN#3018 Organophosphorous Pesticide, liquid, toxic (ICSC, 2004) (UN Recommendation on the Transport of Dangerous Goods). |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Stable to water (water solubility: 145ppm (23degC), Merck (13th, 2001)) |
| 13 | Oxidizing liquids | Not classified | - | - | - | - | No data available, though being organic compounds containing oxygen bound to the elements other than carbon and hydrogen. Classified into Division 6.1 (UN#3018 Organophosphorous Pesticide, liquid, toxic (ICSC, 2004) (UN Recommendation on the Transport of Dangerous Goods). |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no "-O-O-" structure |
| 16 | Corrosive to metals | Not classified | - | - | - | - | The substance acts on iron and steel according to ICSC (2004). Classified into Division 6.1 (UN#3018 Organophosphorous Pesticide, liquid, toxic (ICSC, 2004) (UN Recommendation on the Transport of Dangerous Goods). |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Category 2 |
|
Danger | H300: Fatal if swallowed |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ... |
Based on the rat LD50 (oral route) value of 9.66mg/kg representing the lower of the two testing data, 10mg/kg (RTECS (2006)) and 9.66mg/kg (HSDB (2006)). |
| 1 | Acute toxicity （Dermal） | Category 1 |
|
Danger | H310: Fatal in contact with skin |
P302+P350: IF ON SKIN: Gently wash with plenty of soap and water. P262: Do not get in eyes, on skin, or on clothing. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P322: Specific treatment （see ... on this label）. P361: Remove/Take off immediately all contaminated clothing. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ... |
Based on the LD50 value of 26.4mg/kg calculated from the testing data of rat LD50 (dermal route) of 26.4mg/kg (RTECS (2006)), 31mg/kg (HSDB (2006)) and 108mg/kg (HSDB (2006)). |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Due to the fact that the substance is "liquid" according to the GHS definition and inhalation of its gas is not expected. |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Category 1 |
|
Danger | H330: Fatal if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P284: Wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
Based on the rat LC50 (inhalation of dust/mist) value of 0.05mg/L (4 hours) (HSDB (2006)). |
| 2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | No data available |
| 3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | - | No data available |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Classification not possible due to the insufficiency of data (no data available on in vivo mutagenicity/genotoxicity tests) |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available |
| 8 | Specific target organ toxicity - Single exposure | Category 2 (nervous system) |
|
Warning | H371: May cause damage to organs (nervous system) |
P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P405: Store locked up. P501: Dispose of contents/container to ... |
Based on the description in ICSC (J) (1998): "The substance adversely affects the nervous system; can induce spasm and respiratory failure. As a cholinesterase inhibitor, it may cause loss of consciousness, and in some instances, death. These effects may be delayed." Since the priority rating of the referenced study is 2, the substance is classified into Category 2 (nervous system). |
| 9 | Specific target organ toxicity - Repeated exposure | Category 2 (adrenal gland) |
|
Warning | H373: May cause damage to organs through prolonged or repeated exposure (adrenal gland) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Based on the evidence from animal studies: "changes in the adrenal cortex of males, which included increased incidence and intensity of ceroid pigment and focal hypertrophy and increased severity of nodular hyperplasia" (JMPR 877 (1994)). The effects on experimental animals were observed at dosing levels within the guidance value ranges for Category 2. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |