GHS Classification Result

Chemical Name：Ammonium dodecylbenzenesulphonate (C12)
CAS：1331-61-9

Result：
ID: 346
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Containing no chemical groups with explosive properties
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Classified as "liquid" or "solid" according to GHS definition
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Classified as "liquid" or "solid" according to GHS definition
5 Gases under pressure Not applicable - - - - Classified as "liquid" or "solid" according to GHS definition
6 Flammable liquids Classification not possible (as a liquid) - - - - No data available
7 Flammable solids Classification not possible (as a solid) - - - - No data available
8 Self-reactive substances and mixtures Classification not possible - - - - Classification not possible due to lack of data, though being sulfonyls, containing chemical groups with self-reactive properties
9 Pyrophoric liquids Classification not possible (as a liquid) - - - - No data available
10 Pyrophoric solids Classification not possible (as a solid) - - - - No data available
11 Self-heating substances and mixtures Classification not possible - - - - No data available
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At)
13 Oxidizing liquids Classification not possible (as a liquid) - - - - Classification not possible due to lack of data, though being organic compounds containing oxygen bound to elements other than carbon and hydrogen
14 Oxidizing solids Classification not possible (as a solid) - - - - Classification not possible due to lack of data, though being organic compounds containing oxygen bound to elements other than carbon and hydrogen
15 Organic peroxides Not applicable - - - - Organic compounds containing no "-O-O-" structure
16 Corrosive to metals Classification not possible - - - - No data available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ... 		Based on the LD50 value of 502mg/kg calculated from the testing data of rat LD50 (oral route) of 404mg/kg (males), 409mg/kg (females), 659mg/kg (males), 670mg/kg (females), 760mg/kg (females) and 873mg/kg (males) (CERI-NITE Hazard Assessment No.5 (2005)). (LAS mixtures with carbon chain lengths of 10-14; no data available on ammonium dodecylbenzenesulphonate per se).
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Due to the fact that the substance is "liquid" or "solid"according to the GHS definition and inhalation of its gas is not expected.
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 2 Warning H315: Causes skin irritation P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P362: Take off contaminated clothing and wash before reuse. 		Based on the description in the report on human epidemiological studies (CERI-NITE Hazard Assessment No.5 (2005)): "24 hour application of 1% aqueous solution of LAS induced moderate irritation." The substance is thus considered a moderate irritant (LAS mixtures with carbon chain lengths of 10-14; no data available on ammonium dodecylbenzenesulphonate per se).
3 Serious eye damage/eye irritation Category 2A Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection. 		Based on the description in the report on rabbit eye irritation tests (CERI-NITE Hazard Assessment No.5 (2005)): "Application of 5% solution produced severe congestion and edema." The substance is thus considered a severe irritant (LAS mixtures with carbon chain lengths of 10-13; no data available on ammonium dodecylbenzenesulphonate per se).
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Category 1 Warning H317: May cause an allergic skin reaction P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P333+P313: If skin irritation or rash occurs: Get medical advice/attention.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P272: Contaminated work clothing should not be allowed out of the workplace.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P363: Wash contaminated clothing before reuse.
P501: Dispose of contents/container to ... 		Based on the description in the report on guinea pig skin sensitization tests (CERI Hazard Data 2001-20 (2002) and CERI-NITE Hazard Assessment No.5 (2004)): "Skin sensitization: positive" (linear alkylbenzenesulfonate and its salts (the carbon chain length unknown); No data available on ammonium dodecylbenzenesulphonate per se).
5 Germ cell mutagenicity Classification not possible - - - - Classification not possible due to the insufficiency of data (no definite data are available regarding ammonium dodecylbenzenesulphonate per se). As for linear alkylbenzene sulphonate (LAS) and its salts [carbon chain lengths of 10-14 and their mixtures], no data are available on germ cell mutagenicity tests in vivo, whereas multi-generation mutagenicity tests (dominant lethal tests), somatic cell mutagenicity tests in vivo (micronucleus tests, chromosome aberration tests) and Ames assay gave negative results, described in NTP DB (Access on June, 2006), CERI-NITE Hazard Assessment No.5 (2005) and EHC 169 (1996).
6 Carcinogenicity Classification not possible - - - - Classification not possible based on expert judgment in the absence of existing classification together with the absence of definite data on ammonium dodecylbenzenesulphonate per se. CERI-NITE Hazard Assessment No.5 (2005) presents some data regarding carcinogenicity studies on linear alkylbenzene sulphonate (LAS) and its salts [carbon chain lengths of 10-14 and their mixtures].
7 Reproductive toxicity Classification not possible - - - - Classification not possible due to the insufficiency of data (no definite data are available regarding ammonium dodecylbenzenesulphonate per se). As for linear alkylbenzene sulphonate (LAS) and its salts [carbon chain lengths of 10-14 and their mixtures], there was no evidence of adverse effects on the parental animals and the offspring observed in oral studies, whereas decreased fertility and increased incidence of malformation in the offspring were observed at doses inducing parental toxicity in dermal studies, described in CERI-NITE Hazard Assessment No.5 (2005) and EHC 169 (1996).
8 Specific target organ toxicity - Single exposure Classification not possible - - - - Classification not possible in the absence of data on ammonium undecylbenzenesulfonate per se. Note: As for linear alkylbenzene sulphonate (LAS) and its salts [carbon chain lengths of 10-14 and their mixtures], "clinical symptoms include confusion, vomiting, pharyngal and oral pains, and the tendency of blood pressure to decrease" (NITE Initial Risk Assessment No.5 (2005)).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - Classification not possible due to the fact that the only available data are those for mixtures of C10-14.
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - No data available
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - No data available


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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