Chemical Name：1-(4-biphenylyloxy)-3,3-dimethyl-1-(1H-1,2,4-triazol-1-yl)-2-butanol
CAS：55179-31-2

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Not classified	-	-	-	-	Based on the rat LD50 (oral route) value of >5,000mg/kg (Agricultural Chemical Registration Data (1984)).
1	Acute toxicity （Dermal）	Not classified	-	-	-	-	Based on the rat LD50 (dermal roue) value of >5,000mg/kg (Agricultural Chemical Registration Data (1984)).
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Due to the fact that the substance is a solid according to the GHS criteria and inhalation of its gas is not expected.
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	No data available
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	Classification cannot be determined, though the available rat inhalation study reported the LC50 value of >0.55mg/L (4 hours) (Agricultural Chemical Registration Data (1984)).
2	Skin corrosion/irritation	Not classified	-	-	-	-	Based on no evidence of irritation in rabbit skin irritation tests (Agricultural Chemical Registration Data (1984)).
3	Serious eye damage/eye irritation	Not classified	-	-	-	-	Based on the evidence of mild irritation with a Draize score of <=1, which cleared at 72 hours, observed in rabbit eye irritation tests (Agricultural Chemical Registration Data (1984)).
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available
4	Skin sensitization	Not classified	-	-	-	-	No skin sensitizing potential was found in guinea pig sensitization tests (Agricultural Chemical Registration Data (1984)).
5	Germ cell mutagenicity	Not classified	-	-	-	-	Based on negative data in in vitro reverse mutation tests, in vitro chromosome aberration tests (Agricultural Chemical Registration Data (1984)) and in vivo micronucleus tests on mouse bone marrow cells (Agricultural Chemical Registration Data (1984)).
6	Carcinogenicity	Not classified	-	-	-	-	There was no treatment-related increase in tumor incidence observed in rat and mouse carcinogenicity studies (Agricultural Chemical Registration Data (1984)).
7	Reproductive toxicity	Category 2		Warning	H361: Suspected of damaging fertility or the unborn child	P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ...	Based on the evidence of delayed ossification in the pups, reduced female fertility, increased incidence of resorptions/fetal malformation at doses causing a reduction in parental body weight gain observed in rat/rabbit teratogenicity studies (Agricultural Chemical Registration Data (1984)).
8	Specific target organ toxicity - Single exposure	Classification not possible	-	-	-	-	Insufficient data available.
9	Specific target organ toxicity - Repeated exposure	Classification not possible	-	-	-	-	Insufficient data available.
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Category 2	-	-	H401: Toxic to aquatic life	P273: Avoid release to the environment. P501: Dispose of contents/container to ...	It was classified into Category 2 from 96 hours LC50=3.5mg/L of the fish (Carp) (Agricultural Chemical Registration Data, 2004).
11	Hazardous to the aquatic environment （Long-term）	Category 2		-	H411: Toxic to aquatic life with long lasting effects	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	Although acute toxicity was Category 2 and the bio-accumulation potential was low (BCF=203(Agricultural Chemical Registration Data, 1979)), since there was no rapidly degrading (BIOWIN()), it was classified into Category 2.