Chemical Name:Poly(oxyethylene) octylphenyl ether
CAS:9036-19-5
ID: | 493 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Explosives | Not applicable | - | - | - | - | Containing no chemical groups with explosive properties |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added) |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added) |
5 | Gases under pressure | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added) |
6 | Flammable liquids | Not classified (when 9 moles of ethylene oxide added) | - | - | - | - | The flash point is 296degC (open cup flash test) (when 9 moles of ethylene oxide added) (CERI Hazard Data (2001)) |
7 | Flammable solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added) |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Containing no chemical groups with explosive or self-reactive properties |
9 | Pyrophoric liquids | Classification not possible | - | - | - | - | No data available |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added) |
11 | Self-heating substances and mixtures | Classification not possible (when 9 moles of ethylene oxide added) | - | - | - | - | Test methods applicable to liquid substances are not available (when 9 moles of ethylene oxide added) |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At) |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Organic compounds containing oxygen (but not fluorine and chlorine), with the oxygen bound to carbon and hydrogen (but not to other elements) |
14 | Oxidizing solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added) |
15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no "-O-O-" structure |
16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Acute toxicity (Oral) | Category 4 | Warning | H302: Harmful if swallowed |
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ... |
Based on the rat LD50 (oral route) value of 1,700mg/kg representing the lowest of the testing data, 4,190mg/kg (EO 9), 11,600mg/kg (EO 9) (CERI Hazard Data 2001-42 (2002)), 1,700mg/kg (EO 8-10) and >28,000mg/kg (EO 40) (CERI-NITE Hazard Assessment No.105 (2006)). (Memo) EO: the number of moles of ethylene oxide added. Note: Commercial products typically contains EO chain lengths ranging from 9 to10 (CERI-NITE Hazard Assessment No.105 (2006)). The present substance is thus classified into Category 5 based on the LD50 value for EO 9 (4,190mg/kg). | |
1 | Acute toxicity (Dermal) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Due to the fact that the substance is "liquid" according to the GHS definition (EO 9 and EO40) and inhalation of its gas is not expected. |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | No data available |
2 | Skin corrosion/irritation | Not classified | - | - | - | - | Based on the description in the report on epidemiological studies of human exposure (CERI-NITE Hazard Assessment No.105 (2006)): "OPE with average EO chain lengths of 1, 3, 5, 8-10, 12-13 (i.e., OPE1, OPE3, OPE5, OPE8-10, OPE12-13) caused no primary skin irritation," "OPE with EO chain lengths of 3 and longer showed no primary skin irritation." The materials are thus considered non skin irritants. |
3 | Serious eye damage/eye irritation | Category 2A | Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
Based on the description in the report on rabbit eye irritation tests (CERI Hazard Data 2001-42 (2002)): "Moderately irritating." Also based on the description in the report on rabbit eye irritation tests evaluated according to the Draize scheme (CERI-NITE Hazard Assessment No.105 (2006)): "OPE1 and OPE3 caused mild irritation, whereas OPE5, OPE6-8, OPE8-10 and OPE12-13 caused moderate irritation." Also based on the description in the report on eye irritation tests evaluated according to the Threshold scheme: "OPE1 and OPE3 showed mild irritation; OPE5, OPE8-10 and OPE12-13 showed moderate irritation." The materials are thus considered moderate eye irritants. (Memo) OPEn: compound with the number of EO is n. | |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
4 | Skin sensitization | Classification not possible | - | - | - | - | The materials are considered "non sensitizations" based on the results of skin sensitization tests on human volunteers (CERI-NITE Hazard Assessment No.105 (2006)): "EO chain length of 3 or longer: Negative." However, classification is not possible, with only one set of data showing "negative" available. |
5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Classification not possible due to the insufficiency of data (no data available on in vivo mutagenicity/genotoxicity tests) |
6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | Insufficient data available |
8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | No data available |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | Insufficient data available |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Category 1 | Warning | H400: Very toxic to aquatic life |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
It was classified into Category 1 from 96 hours EC50=0.21mg/L of the algae (Selenastrum) (CERI/NITE Hazard Assessment Report (preliminary version), 2006). | |
11 | Hazardous to the aquatic environment (Long-term) | Category 1 | Warning | H410: Very toxic to aquatic life with long lasting effects |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
Although acute toxicity is Category 1 and bio-accumulation is low (BCF<31(Existing Chemical Safety Inspections Data, )), since there was no rapidly degrading (the decomposition by BOD: 22%(Existing Chemical Safety Inspections Data)), it was classified into Category 1. |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |