GHS Classification Result

Chemical Name:Poly(oxyethylene) octylphenyl ether
CAS:9036-19-5

Result:
ID: 493
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Containing no chemical groups with explosive properties
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added)
5 Gases under pressure Not applicable - - - - Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added)
6 Flammable liquids Not classified (when 9 moles of ethylene oxide added) - - - - The flash point is 296degC (open cup flash test) (when 9 moles of ethylene oxide added) (CERI Hazard Data (2001))
7 Flammable solids Not applicable - - - - Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added)
8 Self-reactive substances and mixtures Not applicable - - - - Containing no chemical groups with explosive or self-reactive properties
9 Pyrophoric liquids Classification not possible - - - - No data available
10 Pyrophoric solids Not applicable - - - - Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added)
11 Self-heating substances and mixtures Classification not possible (when 9 moles of ethylene oxide added) - - - - Test methods applicable to liquid substances are not available (when 9 moles of ethylene oxide added)
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At)
13 Oxidizing liquids Not applicable - - - - Organic compounds containing oxygen (but not fluorine and chlorine), with the oxygen bound to carbon and hydrogen (but not to other elements)
14 Oxidizing solids Not applicable - - - - Classified as "liquid" according to GHS definition (when 9 moles of ethylene oxide added)
15 Organic peroxides Not applicable - - - - Organic compounds containing no "-O-O-" structure
16 Corrosive to metals Classification not possible - - - - No data available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ...
Based on the rat LD50 (oral route) value of 1,700mg/kg representing the lowest of the testing data, 4,190mg/kg (EO 9), 11,600mg/kg (EO 9) (CERI Hazard Data 2001-42 (2002)), 1,700mg/kg (EO 8-10) and >28,000mg/kg (EO 40) (CERI-NITE Hazard Assessment No.105 (2006)). (Memo) EO: the number of moles of ethylene oxide added. Note: Commercial products typically contains EO chain lengths ranging from 9 to10 (CERI-NITE Hazard Assessment No.105 (2006)). The present substance is thus classified into Category 5 based on the LD50 value for EO 9 (4,190mg/kg).
1 Acute toxicity (Dermal) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Due to the fact that the substance is "liquid" according to the GHS definition (EO 9 and EO40) and inhalation of its gas is not expected.
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Not classified - - - - Based on the description in the report on epidemiological studies of human exposure (CERI-NITE Hazard Assessment No.105 (2006)): "OPE with average EO chain lengths of 1, 3, 5, 8-10, 12-13 (i.e., OPE1, OPE3, OPE5, OPE8-10, OPE12-13) caused no primary skin irritation," "OPE with EO chain lengths of 3 and longer showed no primary skin irritation." The materials are thus considered non skin irritants.
3 Serious eye damage/eye irritation Category 2A Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
Based on the description in the report on rabbit eye irritation tests (CERI Hazard Data 2001-42 (2002)): "Moderately irritating." Also based on the description in the report on rabbit eye irritation tests evaluated according to the Draize scheme (CERI-NITE Hazard Assessment No.105 (2006)): "OPE1 and OPE3 caused mild irritation, whereas OPE5, OPE6-8, OPE8-10 and OPE12-13 caused moderate irritation." Also based on the description in the report on eye irritation tests evaluated according to the Threshold scheme: "OPE1 and OPE3 showed mild irritation; OPE5, OPE8-10 and OPE12-13 showed moderate irritation." The materials are thus considered moderate eye irritants. (Memo) OPEn: compound with the number of EO is n.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - The materials are considered "non sensitizations" based on the results of skin sensitization tests on human volunteers (CERI-NITE Hazard Assessment No.105 (2006)): "EO chain length of 3 or longer: Negative." However, classification is not possible, with only one set of data showing "negative" available.
5 Germ cell mutagenicity Classification not possible - - - - Classification not possible due to the insufficiency of data (no data available on in vivo mutagenicity/genotoxicity tests)
6 Carcinogenicity Classification not possible - - - - No data available
7 Reproductive toxicity Classification not possible - - - - Insufficient data available
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - Insufficient data available
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 1 Warning H400: Very toxic to aquatic life P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
It was classified into Category 1 from 96 hours EC50=0.21mg/L of the algae (Selenastrum) (CERI/NITE Hazard Assessment Report (preliminary version), 2006).
11 Hazardous to the aquatic environment (Long-term) Category 1 Warning H410: Very toxic to aquatic life with long lasting effects P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
Although acute toxicity is Category 1 and bio-accumulation is low (BCF<31(Existing Chemical Safety Inspections Data, )), since there was no rapidly degrading (the decomposition by BOD: 22%(Existing Chemical Safety Inspections Data)), it was classified into Category 1.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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