Chemical Name:Diisobutyl phthalate
CAS:84-69-5
ID: | 549 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Explosives | Not applicable | - | - | - | - | Containing no chemical groups with explosive properties |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
5 | Gases under pressure | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
6 | Flammable liquids | Not classified | - | - | - | - | The flash point is 185degC (ICSC (2001)) |
7 | Flammable solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Containing no chemical groups with explosive or self-reactive properties |
9 | Pyrophoric liquids | Not classified | - | - | - | - | Not pyrophoric when in contact with air at ordinary temperatures (flash point: 400degC (ICSC, 2001)) |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Containing no metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At) |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Organic compounds containing oxygen (but not fluorine and chlorine), with the oxygen bound to carbon and hydrogen (but not to other elements) |
14 | Oxidizing solids | Not applicable | - | - | - | - | Classified as "liquid" according to GHS definition |
15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no "-O-O-" structure |
16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Not classified | - | - | - | - | Based on the rat LD50 (oral route) value of ca.10,400mg/kg representing the lower of the two testing data, ca.10,400mg/kg (IUCLID (2000)) and 15,000mg/kg (RTECS (2006)). |
1 | Acute toxicity (Dermal) | Not classified | - | - | - | - | Based on the guinea pig LD50 (dermal route) value of 10,000mg/kg (RTECS (2006)). |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Due to the fact that the substance is "liquid" according to the GHS definition and inhalation of its gas is not expected. |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | No data available |
2 | Skin corrosion/irritation | Not classified | - | - | - | - | Based on the description in the report on rabbit skin irritation tests performed in accordance with OECD Test Guideline 404 (IUCLID (2000)): "Not irritating." |
3 | Serious eye damage/eye irritation | Not classified | - | - | - | - | Based on the description in the report on rabbit eye irritation tests performed in accordance with OECD Test Guideline 405 (IUCLID (2000)): "Not irritating." |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Classification not possible due to lack of data on in vivo tests. |
6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | Insufficient data available. |
8 | Specific target organ toxicity - Single exposure | Category 3 (Narcotic effects, Respiratory tract irritation) | Warning |
H335: May cause respiratory irritation (narcotic effects, respiratory tract irritation) H336: May cause drowsiness or dizziness (narcotic effects, respiratory tract irritation) |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ... |
Based on the evidence from animal studies including "coma, respiratory tract irritation" (RTECS, (2006)). | |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | Insufficient data available |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Category 1 | Warning | H400: Very toxic to aquatic life |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
It was classified into Category 1 from 96 hours LC50=0.9mg/L of the fish (Fathead Minnows) (ECETOC TR91, 2003). | |
11 | Hazardous to the aquatic environment (Long-term) | Category 1 | Warning | H410: Very toxic to aquatic life with long lasting effects |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
Although acute toxicity was Category 1 and there was rapidly degrading (the decomposition by BOD: 98%(Existing Chemical Safety Inspections Data)), since there was bio-accumulation (log Kow=4.11 (PHYSPROP Database (2005)), it was classified into Category 1. |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |