Chemical Name:Monosodium sulfite
CAS:7631-90-5
ID: | 639 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Aqueous solution |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Aqueous solution |
5 | Gases under pressure | Not applicable | - | - | - | - | Aqueous solution |
6 | Flammable liquids | Not classified | - | - | - | - | Aqueous solution. Non-combustible |
7 | Flammable solids | Not applicable | - | - | - | - | Aqueous solution |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
9 | Pyrophoric liquids | Not classified | - | - | - | - | Non-combustible solution |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Aqueous solution |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | The aqueous solution is stable. |
13 | Oxidizing liquids | Not classified | - | - | - | - | Reducing substance |
14 | Oxidizing solids | Not applicable | - | - | - | - | Aqueous solution |
15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic substance |
16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Acute toxicity (Oral) | Category 4 | Warning | H302: Harmful if swallowed |
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ... |
Category 4 based on SPECIES: Rat; ENDPOINT: LD50; VALUE (Average): 1310mg/kg | |
1 | Acute toxicity (Dermal) | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Aqueous solution |
1 | Acute toxicity (Inhalation: Vapours) | Not applicable | - | - | - | - | Aqueous solutions. Volatilizing is mainly vapor. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | It has not stimulation in animal experiments. But there is information that it causes irritation on humans with concentrated solution, and it is designated as class 8 also in UN hazardous material transportation. |
3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | - | Although there is case of humans (ACGIH (2002)), it is supposed that the animal experiment result by solution is no stimulating. |
4 | Respiratory sensitization | Category 1 | Danger | H334: May cause allergy or asthma symptoms or breathing difficulties if inhaled |
P304+P341: IF INHALED: If breathing is difficult, remove victim to fresh air and keep at rest in a position comfortable for breathing. P342+P311: If experiencing respiratory symptoms: Call a POISON CENTER or doctor/physician. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P285: In case of inadequate ventilation wear respiratory protection. P501: Dispose of contents/container to ... |
As human epidemiology information, a small number of allergy case caused by inhalation, skin contact and intake has been reported. It is said that it happens to the humans of sulfite oxidase deficiency. Although the occurrence rate was not high, it was referred to as Category 1 by expert judgment. | |
4 | Skin sensitization | Category 1 | Warning | H317: May cause an allergic skin reaction |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P333+P313: If skin irritation or rash occurs: Get medical advice/attention. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment (see ... on this label). P363: Wash contaminated clothing before reuse. P501: Dispose of contents/container to ... |
As human epidemiology information, a small number of allergy case caused by inhalation, skin contact and intake has been reported. It is said that it happens to the humans of sulfite oxidase deficiency. Although the occurrence rate was not high, it was referred to as Category 1 by expert judgment. | |
5 | Germ cell mutagenicity | Not classified | - | - | - | - | The in vivo result was, "it gave negative for the mouse and over generation mutagenicity tests of mouse." Although we found the positive result for in vitro test, we classified it as "Out Of Category" by the technical guideline. [Based on the expert's opinion, we corrected the basic sentences.] |
6 | Carcinogenicity | Not classified | - | - | - | - | Since it is class 3 by IARC and is A4 by ACGIH, it carried out "Category Outside." |
7 | Reproductive toxicity | Not classified | - | - | - | - | Since the adverse effects was not reported in multi-generation test, it carried out "Category Outside." |
8 | Specific target organ toxicity - Single exposure | Category 3 (Respiratory tract irritation) | Warning | H335: May cause respiratory irritation (respiratory tract irritation) |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ... |
Since there was respiratory stimulas information by the human aerosol exposure, it was set as category 3 (respiratory tract irritation). | |
9 | Specific target organ toxicity - Repeated exposure | Category 1 (respiratory system) | Danger | H372: Cause damage to organs through prolonged or repeated exposure (respiratory system) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
It was classified to as "Category 1" since there is a report of an asthmatic among laundry workers and a food ingesting person (ACGIH (2001)). (Modified by expert judgment) | |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Not classified | - | - | - | - | It carried out the outside of Category from 48-hour LC50=119000microg/L of Crustacea (Daphnia magna), and others (AQUIRE, 2003). |
11 | Hazardous to the aquatic environment (Long-term) | Not classified | - | - | - | - | Since not water-insoluble (aqueous solubility =540 g/L (IUCLID, 2000)) and acute toxicity is low. |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model SDS by MHLW |
MHLW Website (in Japanese Only) |