GHS Classification Result

Chemical Name:Distillates (petroleum), solvent-refined heavy paraffinic; Distillates (petroleum), solvent-refined light naphthenic; Lubricating oils (petroleum), C15-30, hydrotreated neutral oil-based; Lubricating oils (petroleum), C20-50, hydrotreated neutral oil-based; Petroleum; Paraffin oils
CAS:8002-05-9,8012-95-1,64741-88-4,64741-97-5,72623-86-0,72623-87-1

Result:
ID: 719
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Classification not possible - - - - No data available
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Liquid (room temperature)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Liquid (room temperature)
5 Gases under pressure Not applicable - - - - Liquid (room temperature)
6 Flammable liquids Not classified - - - - Not classified because of its flash point: 149-232degC (NFPA, 13th, 2002)
7 Flammable solids Not applicable - - - - Liquid (room temperature)
8 Self-reactive substances and mixtures Classification not possible - - - - No data available
9 Pyrophoric liquids Not classified - - - - The ignition points is 260 - 371 degC (NFPA (13th, 2002)), and exceeds 70 degC.
10 Pyrophoric solids Not applicable - - - - Liquid (room temperature)
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to liquid substances are not available
12 Substances and mixtures which, in contact with water, emit flammable gases Classification not possible - - - - No data available
13 Oxidizing liquids Classification not possible - - - - No data available
14 Oxidizing solids Not applicable - - - - Liquid (room temperature)
15 Organic peroxides Classification not possible - - - - No data available
16 Corrosive to metals Classification not possible - - - - No data available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Not classified - - - - SPECIES: Rat ENDPOINT: LD50 VALUE: > 5000 mg/kg REFERENCE SOURCE: IUCLID (2000)
1 Acute toxicity (Dermal) Not classified - - - - Based on rat LD50 >5000mg/kg (IUCLID (2000)), it was set as the outside of Category.
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Liquid (room temperature)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Category 4 Warning H332: Harmful if inhaled P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
Category 4 because of "SPECIES: Rat; ENDPOINT: LC50 = 2.18 mg/L." (IUCLID, 2000)
2 Skin corrosion/irritation Category 3 - Warning H316: Causes mild skin irritation P332+P313: If skin irritation occurs: Get medical advice/attention. It was classified as Category 3 based on several reports which observed mild irritation in rabbit tests (IUCLID (2000)).
3 Serious eye damage/eye irritation Category 2B - Warning H320: Causes eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
By the test using a rabbit, there was a report (IUCLID (2000)) described to be mild irritation. So it was set as Category 2B.
4 Respiratory sensitization Classification not possible - - - - No data
4 Skin sensitization Not classified - - - - In multiple tests(including the maximization test) based on OECD Guideline 406 using the guinea pigs, a result that none of them had the sensitization was obtained (IUCLID (2000)), and therefore it was put outside of the Category.
5 Germ cell mutagenicity Category 2 Warning H341: Suspected of causing genetic defects P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ...
Based on the increase in the abnormal cells in the cytogenetic study [chromosomal aberration test] (somatic cell in vivo mutagenicity test) using the rat (IUCLID (2000)), and based on the fact that increase was observed in frequency of the chromosomal aberration in the peripheral blood lymphocyte of the human who received occupational exposure (IARC suppl.7 (1987)), and on the fact that there being no information about the productive cell in vivo genotoxicity study. So we classified it as Category 2.
6 Carcinogenicity Not classified (Highly refined oil), Category 1A (Crude oil or Slightly refined oil) Danger H350: May cause cancer (Crude oil or Slightly refined oil) P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ...
Un-refined or slight processed oil is classified into group 1, and highly refined oil is into group 3 (IARC (1987)), and the proposal of ACGIH (2006) can also be said to be the almost same category. It is classified into the 1st group according to Occupational Health Society (1977) as un-refined and a half-refined article. As mentioned above, according to the classification of IARC which the classification has decided, highly refined oil is set to outside of category and unrefined oils or low grade treated oil to Category 1A.
7 Reproductive toxicity Classification not possible - - - - No data available
8 Specific target organ toxicity - Single exposure Category 2 (lung) Warning H371: May cause damage to organs (lung) P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P405: Store locked up.
P501: Dispose of contents/container to ...
There is the statement that there is the grossly, histopathological acute changes (details unknown) in dependance to dose (1.51 - 5.05mg/L) in the rat test of inhalation exposure (IUCLID (2000)), it is classified into Category 3 (lung).
9 Specific target organ toxicity - Repeated exposure Category 1 (lung, skin) Danger H372: Cause damage to organs through prolonged or repeated exposure (lung, skin) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ...
It was classified to as Category 1 (lungs, skin) since that pulmonary fibrosis, lipid pneumonias and lipogranuloma of lungs are reported in humans who received exposure of the mineral oils or the mist over many years (ACGIH (2001) and IARC 33 (1984),EHC 20 (1982)), and generation of the serious folliculitis is reported in the epidemiological study by occupational exposure to cutting oil (IARC 33 (1984)).
10 Aspiration hazard Category 1 Danger H304: May be fatal if swallowed and enters airways P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P331: Do NOT induce vomiting.
P405: Store locked up.
P501: Dispose of contents/container to ...
It was classified into Category 1 based on the reports that ingestion of mineral oil causes the aspiration into the lungs, and as a result it occures the pneumonie huileuses or chemical pneumonia in the human (EHC 20 (1982), IARC 33 (1984), ICSC (2001), ACGIH (2001)).

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - - No data available
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations


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