GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：Zinc oxide
CAS：1314-13-2
Result：
| ID: | 737 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Solid (GHS definition) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Solid (GHS definition) |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 7 | Flammable solids | Not classified | - | - | - | - | Non-combustible substance |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 10 | Pyrophoric solids | Not classified | - | - | - | - | Non-combustible |
| 11 | Self-heating substances and mixtures | Not classified | - | - | - | - | Not combustible |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Not classified because of a water-insoluble substance practically |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 14 | Oxidizing solids | Not classified | - | - | - | - | It reacts at a high temperature with metals such as magnesium and aluminum with a higher ionization tendency (ICSC (2004), but does not meet the definition of oxidativity. |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic substance |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to solid substances are not available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Not classified | - | - | - | - | Not classified because of SPECIES: Rat; ENDPOINT: LD50; >5000 mg/kg; REFERENCE SOURCE: EU-RAR 43 (2004) |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 1 | Acute toxicity （Inhalation: Vapours） | Not applicable | - | - | - | - | The vapor pressure around room temperature is very low. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Category 5 | - | Warning | H333: May be harmful if inhaled | P304+P312: IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. | Since it was data of 5.7 or more mg/L in the rat (EU-RAR 43 (2004)), it was set as category 5. |
| 2 | Skin corrosion/irritation | Not classified | - | - | - | - | Since the experiment of the rabbit quoted shows no stimulation as a result (ACGIH (2003) and EU-RAR 43 (2004)), it was classified as "out of Category". |
| 3 | Serious eye damage/eye irritation | Not classified | - | - | - | - | In the report of three affairs currently recorded and selected by EU-RAR (2004), two affairs had a very slight stimulus and one affair did not stimulate. And EU-RAR (2004) had judged no stimulating. So it was set as "Outsaide of Category ." |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | Since there is no data, respiratory sensitization cannot be classified. |
| 4 | Skin sensitization | Not classified | - | - | - | - | Skin sensitization was put outside of the division according to the comprehensive judgment of EU-RAR (2004). |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | In the result of the in vivo chromosomal aberration test it gave positive although it was doubtfull, and for the in vitro results we found both positive results and negative results. We have no enough data for which we can judge. |
| 6 | Carcinogenicity | Not classified | - | - | - | - | U.S. EPA is considering it as Group D. Since there was nothing that suggests carcinogenicity also to an animal data, it considered as "Category Outside." |
| 7 | Reproductive toxicity | Not classified | - | - | - | - | Not classified following to the overall judgment (EU-RAR, 2004) |
| 8 | Specific target organ toxicity - Single exposure | Category 1 (Inhalation: systemic toxicity) |
|
Danger | H370: Causes damage to organs (Inhalation: systemic toxicity) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
Since producing metal FUMU heat by inhalations of fine dusts was known, it is classified into "Category 1." Respiratory irritation is not acknowledged (EU-RAR 43 (2004)). |
| 9 | Specific target organ toxicity - Repeated exposure | Category 1 (Inhalation: lung) |
|
Danger | H372: Cause damage to organs through prolonged or repeated exposure (Inhalation: lung) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Since the effect on lungs was seen in repetitive inhalation exposure to the guinea pigs and the rat, it was classified into "Category 1." |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Category 1 |
|
Warning | H400: Very toxic to aquatic life |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
It was classified into Category 1 from 72-hour EC50=0.17mg/L (zinc-oxide concentration equivalent: 0.21mg/L) of algae (Selenastrum) (EHC221, 2001). |
| 11 | Hazardous to the aquatic environment （Long-term） | Category 1 |
|
Warning | H410: Very toxic to aquatic life with long lasting effects |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
Classified into Category 1, since acute toxicity was Category 1, and it is a metallic compound, behavior in water is unknown, though less bioaccumulative (BCF=217 (existing chemical safety inspections data)). |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |