GHS Classification Result

Chemical Name：Cyclopentane
CAS：287-92-3

Result：
ID: 770
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Liquid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Liquid (GHS definition)
5 Gases under pressure Not applicable - - - - Liquid (GHS definition)
6 Flammable liquids Category 2 Danger H225: Highly flammable liquid and vapour P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P370+P378: In case of fire: Use ... for extinction.
P403+P235: Store in a well-ventilated place. Keep cool.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof electrical/ventilating/lighting/.../equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ... 		Category 2 because of its flash point: -42 to -7degC, initial Boiling point: 49 to 49.3degC
7 Flammable solids Not applicable - - - - Liquid (GHS definition)
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9 Pyrophoric liquids Not classified - - - - The ignition points is 361 - 385 degC (ICSC (1994), the dangerous decibel (the 2nd edition, 1993), a pocket book books (1997))
10 Pyrophoric solids Not applicable - - - - Liquid (GHS definition)
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to liquid substances are not available
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - - Organic compounds containing no oxygen, fluorine and chlorine.
14 Oxidizing solids Not applicable - - - - Liquid (GHS definition)
15 Organic peroxides Not applicable - - - - Organic compounds containing no -0-0- structure
16 Corrosive to metals Classification not possible - - - - No data available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Not classified - - - - Not classified because of SPECIES: Rat; ENDPOINT: LD50; VALUE: 11400 mg/kg; REFERENCE SOURCE: RTECS(2004)
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Liquid (GHS definition)
1 Acute toxicity （Inhalation: Vapours） Category 5 - Warning H333: May be harmful if inhaled P304+P312: IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell. Rat inhalation LC50 = 106mg/L (RTECS (2004)). The administration period was unknown from the writing. But exposure for 30 minutes or more with this concentration will classify as Category 5, it was classified as Category 5. In addition, the saturated concentration of this product is 4.1* 10^5ppm (equivalent value: 1.2 * 10^6mg/L), and it is presumed that the inhalation test is done in the state of steam.
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available
2 Skin corrosion/irritation Category 2 Warning H315: Causes skin irritation P302+P352: IF ON SKIN: Wash with plenty of soap and water.
P332+P313: If skin irritation occurs: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P321: Specific treatment （see ... on this label）.
P362: Take off contaminated clothing and wash before reuse. 		Since there is a description that contact with this product may stimulate human skin (SITTIG (4th, 2002), HSFS (2001), ICSC (J) (1994)), it was classified as Category 2.
3 Serious eye damage/eye irritation Category 2A-2B Warning H319: Causes serious eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection. 		Since there is the description that the contact to this product and vapor stimulate the human eyes (PATTY (5th, 2001); ICSC (J) (1994); HSFS (2001); SITTIG (4th, 2002)), it was set as Category 2A-2B. [Indications] in the case that subdividing are necessary, it is more desirable to be set as Category 2A from the viewpoint of safety.
4 Respiratory sensitization Classification not possible - - - - No data
4 Skin sensitization Classification not possible - - - - Although there is a description that dermatitis is caused by long-term contacts in the documents of Priority 1 (PATTY (5th, 2001)) and 2 others(ICSC(J)(1994);IUCLID (2000)), since it is impossible to distinguish if it is just stimulative or allergic, it was decided that it could not be classified due to lack of data.
5 Germ cell mutagenicity Classification not possible - - - - No data available
6 Carcinogenicity Classification not possible - - - - No data available
7 Reproductive toxicity Classification not possible - - - - No data available
8 Specific target organ toxicity - Single exposure Category 3 （Narcotic effects, Respiratory tract irritation） Warning H335: May cause respiratory irritation (narcotic effects, respiratory tract irritation)
H336: May cause drowsiness or dizziness (narcotic effects, respiratory tract irritation) 		P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P405: Store locked up.
P501: Dispose of contents/container to ... 		There is the description that the influence of the central nerve, such as giddiness, clouding of consciousness, a coma, etc. is seen as a result of exposures to this product in Priority 1 (PATTY (5th, 2001)). Moreover, respiratory irritation was indicated (PATTY (5th, 2001), ICSC (J) (1994)), it is classified into Category 3 ( anesthesia action, respiratory irritation).
9 Specific target organ toxicity - Repeated exposure Not classified - - - - In the 12-week repetition examination in a rat of high inhalation exposure which corresponds outside the Category (PATTY (5th, 2001)), only the suppression of weight gain was observed, therefore it was classified outside of Category.
10 Aspiration hazard Category 1 Danger H304: May be fatal if swallowed and enters airways P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P331: Do NOT induce vomiting.
P405: Store locked up.
P501: Dispose of contents/container to ... 		There is the descriptions that aspiration causes chemical pneumonia (the documents of Priority 1 (PATTY (5th, 2001)) and 2 (ICSC(J) (1994); SITTIG (4th, 2002))), therefore we classified it as Category 1.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Category 3 - - H402: Harmful to aquatic life P273: Avoid release to the environment.
P501: Dispose of contents/container to ... 		It was classified into Category 3 from 48-hour EC50=10.5mg/L of Crustacea (Daphnia magna) (IUCLID, 2000).
11 Hazardous to the aquatic environment （Long-term） Category 3 - - H412: Harmful to aquatic life with long lasting effects P273: Avoid release to the environment.
P501: Dispose of contents/container to ... 		Classified into Category 3, since acute toxicity was Category 3 and rapid degradability is unknown, though supposed less bio-accumulative (log Kow=3 (PHYSPROP Database, 2005)).


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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