GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：caesium hydroxide
CAS：21351-79-1
Result：
| ID: | 812 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Solid (GHS definition) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Solid (GHS definition) |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 7 | Flammable solids | Not classified | - | - | - | - | Non-combustible substance |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 10 | Pyrophoric solids | Not classified | - | - | - | - | Non-combustible |
| 11 | Self-heating substances and mixtures | Not classified | - | - | - | - | Not combustible |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Although it reacts violently with water, what is generated is heat and is not flammable gas. (Sitting (47th. 2002)) |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 14 | Oxidizing solids | Not classified | - | - | - | - | Although it contains oxygen, cesium is the most stable metal in the state of monovalence, and does not give oxygen to other substances. |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic substance |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Although it is a caustic substances to the extent that it can be storaged only with the container of silver or platinum (Sittig (47th, 2002)), the corrosion-rate data about steel and aluminum are not obtained. It is estimated to be in Category 1. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Category 4 |
|
Warning | H302: Harmful if swallowed |
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ... |
Since data of 570mg/kg (RTECS (2004)) and 1026mg/kg (ACGIH (2001)) were found in rat LD50, they were set as Category 4. |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | Steam inhalation cannot be performed because it is a nonvolatile solid. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Category 1 |
|
Danger | H330: Fatal if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P284: Wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
The value of 0.02mg/L was found in the inhalation LC50 data in which the animal and time of exposure was unknown (RTECS (2004)), it was considered as dust inhalation "category 1". Data that human LC50 (?): 0.005mg/L was also in the same former literature. |
| 2 | Skin corrosion/irritation | Category 1B |
|
Danger | H314: Causes severe skin burns and eye damage |
P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P321: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ... |
There are Mild reports when it attaches to the skin of a rabbit in the state of the dry crystal (RTECS (2004)). But it indicates significant corrosive (ACGIH (2001)) when it is absorbed moisture, or in aqueous solutions. So it was set as Category 1. The warnings and the cautions about corrosion behavior for humans are also indicated by individual references (ACGIH (2001), HSFS (1998), Sitting (47th, 2002)). It is referred to as class 8PG II in the U.N. transportation advice. GHS Category for the purpose of transportation is set as 1B. |
| 3 | Serious eye damage/eye irritation | Category 1 |
|
Danger | H318: Causes serious eye damage |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. |
It is indicated that puting into the eyes of the rabbit causes the intense stimulus (ACGIH (2001)), and into people's eyes also causes stimulating and burns (Sitting (47th.2002), HSFS (1998)). Moreover, since skin corrosivity and irritation were set to "Category 1", eyes were also set as "Category 1". |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | There were no data and we could not classify it. |
| 4 | Skin sensitization | Not classified | - | - | - | - | We classified it as "Out Of Category" since we have a report (ACGIH (2001)) that skin sensitization was not acknowledged for the experiment with the guinea pigs. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
| 8 | Specific target organ toxicity - Single exposure | Category 3 （Respiratory tract irritation） |
|
Warning | H335: May cause respiratory irritation (respiratory tract irritation) |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ... |
No case reports are found that should make us classify it into Category 1 or 2. Sitting (54th, 2002) and HSFS (1998) have the descriptions about stimuli to upper respirators (nose, throat and trachea). Although the description is listed in the data sheet that does not clarify the basis and source, we adopted "Category 3 (respiratory irritant)" since this substance is the strongest alkali. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | The influence on the respiratory systems, such as lungs and a trachea, by prolonged exposure of humans is indicated (Sitting (47th.2002) and HSFS (1998)). Moreover, in the two inhalation experiments of rats, effects on the central nervous systems, on heart and blood by the exposure concentration within the guidance value of Category 1 are separately reported (RTECS (2004)), but use was withheld since there was no detailed description. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
|
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
|
Reference Manual |
|
|
Definitions / Abbreviations |
|
|
Model SDS by MHLW |
MHLW Website （in Japanese Only） |