GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：Petroleum benzine
CAS：
Result：
| ID: | 821 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Classification not possible | - | - | - | - | No data available |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Liquid (room temperature) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid (room temperature) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Liquid (room temperature) |
| 6 | Flammable liquids | Category 1 |
|
Danger | H224: Extremely flammable liquid and vapour |
P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
It was classified as Category 1 based on flash point: about -40 degC (solvent pocket book (1997)) and initial boiling point: 35 degC (Merck (13th, 2001)). |
| 7 | Flammable solids | Not applicable | - | - | - | - | Liquid (room temperature) |
| 8 | Self-reactive substances and mixtures | Classification not possible | - | - | - | - | No data available |
| 9 | Pyrophoric liquids | Not classified | - | - | - | - | Based on the ignition points of about 280 degC (> 75 degC) (pocket book books (1997)), it was classified as outside of Category. |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid (room temperature) |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Classification not possible | - | - | - | - | No data available |
| 13 | Oxidizing liquids | Classification not possible | - | - | - | - | No data available |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid (room temperature) |
| 15 | Organic peroxides | Classification not possible | - | - | - | - | No data available |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Not classified | - | - | - | - | SPECIES: Rat ENDPOINT: LD50 VALUE: > 16 g/kg REFERENCE SOURCE: EHC20 (1982) |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | Insufficient data available |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Liquid (room temperature) |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | Insufficient data available |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | Insufficient data available |
| 2 | Skin corrosion/irritation | Category 3 | - | Warning | H316: Causes mild skin irritation | P332+P313: If skin irritation occurs: Get medical advice/attention. | By statement that petroleum benzins contained hexane and heptane as the main components, and that although pentane, hexane, heptane and octane caused erythema, hyperemia, swelling, and pigmentation to human skin. But when hexane and heptane were eliminated, the pain decreased in the short time and the discontinuation of exposure recovered unfounded (NIOSH (1997)). So it was set as Category 3. |
| 3 | Serious eye damage/eye irritation | Category 2A-2B |
|
Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
There is the description that petroleum benzins's principal components are hexanes and heptanes, and for hexane the irritation to eyes is acknowledged in evidence of exposure in humans (vol.1 (2002) of MOE Risk Assessment), and the description that mild irritation are acknowledged in rabbits. So it was set as Category 2A-2B. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available |
| 8 | Specific target organ toxicity - Single exposure | Category 3 （Narcotic effects） |
|
Warning | H336: May cause drowsiness or dizziness (narcotic effects) |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ... |
The rat inhalation study indicated a coma during the exposure periods, and it was set as Category 3 (anaesthetic) based on the report (Industrial Medicine (1970)) that it recovered in several hours after the exposure stops. |
| 9 | Specific target organ toxicity - Repeated exposure | Category 1 (nervous system) |
|
Danger | H372: Cause damage to organs through prolonged or repeated exposure (nervous system) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
It was classified into Category 1 (nerve systems) based on that petroleum benzins is a mixture of pentane, hexane, and heptane etc. (solvent pocket book (1997)), and the statement showing that there are many case reports on the symptoms of polyneuropathy (poluneuropathy) developed in the humans exposed to the solvent including high-concentration hexane in the long-term (EHC20 (1982)). In addition, although it is a given dose beyond the maximum of a Category 2 guidance value, the symptom as humans that the repeat administration studies using a rat is also the same is observed (EHC20 (1982)). |
| 10 | Aspiration hazard | Category 1 |
|
Danger | H304: May be fatal if swallowed and enters airways |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P331: Do NOT induce vomiting. P405: Store locked up. P501: Dispose of contents/container to ... |
Since the petroleum benzin consists of hexane and heptane, and hexane is hydrocarbon and its dynamic viscosity at 40 degrees C is 20.5mm 2/s or less, we classified it as Category 1. There is a description of chemical pneumona by aspiration of hexane on the rat (DFGOT vol.4 (1992)). |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |