Chemical Name:Heptane
CAS:142-82-5
ID: | 946 |
Classifier: | Inter-ministerial Committee on GHS |
Year Classified: | FY2006 |
Reference Manual: | GHS Classification Manual (10 Feb, 2006) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Liquid (GHS definition) |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid (GHS definition) |
5 | Gases under pressure | Not applicable | - | - | - | - | Liquid (GHS definition) |
6 | Flammable liquids | Category 2 | Danger | H225: Highly flammable liquid and vapour |
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
Flash point: <23degC, Initial boiling point: >35degC, UNRTDG Class: 3, PG II | |
7 | Flammable solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
9 | Pyrophoric liquids | Not classified | - | - | - | - | Flash point: 204degC (NFPA, 12th, 1997, p.325-57) |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Organic compounds containing no oxygen, fluorine and chlorine. |
14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
15 | Organic peroxides | Not applicable | - | - | - | - | Containing no -0-0- structure |
16 | Corrosive to metals | Not classified | - | - | - | - | UNRTDG Class: 3 |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Acute toxicity (Oral) | Classification not possible | - | - | - | - | No data available |
1 | Acute toxicity (Dermal) | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Liquid (GHS definition) |
1 | Acute toxicity (Inhalation: Vapours) | Not classified | - | - | - | - | Based on mouse LC50 (2 hours) value: 75mg/L (4-hour equivalent: 53mg/L) (PATTY 4th, 1994), which vapor pressure indicate steam with almost no mist. It was classified by the ppm concentration standard. Since 53mg/L was converted to 12927ppm with the conversion factor (1ppm=4.1mg/m3), it was classified as out of Category. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | No data available |
2 | Skin corrosion/irritation | Category 2 | Warning | H315: Causes skin irritation |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment (see ... on this label). P362: Take off contaminated clothing and wash before reuse. |
It was set as Category 2 from description that irritant was acknowledged by the cutaneous contact as effect of the humans (DFGOT (vol.11, 1998) and Occupational Health Recommendation of Occupational Exposure Limits(1988)). | |
3 | Serious eye damage/eye irritation | Category 2A-2B | Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
We classified it as Category 2A-2B based on the description that mild ocular irritation was acknowledged in the ocular irritation tests using the rabbits (IUCLID (2000)) and on the descriptions that it stimulated the eyes (ICSC (J), (1997) and SITTIG (4th, 2002)). | |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
6 | Carcinogenicity | Not classified | - | - | - | - | Since it was classified into D in EPA (1996) (IRIS, 2005), it was considered as the outside of Category. |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available |
8 | Specific target organ toxicity - Single exposure | Category 3 (Respiratory tract irritation, Narcotic effects) | Warning |
H336: May cause drowsiness or dizziness (respiratory tract irritation, narcotic effects) H335: May cause respiratory irritation (respiratory tract irritation, narcotic effects) |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ... |
Because of descriptions in ACGIH (7th, 2001), DFGOT (vol.11, 1998), PATTY (4th, 1994) and Japan Society for Occupational Health recommendation (1988) referring to that anesthetic actions and respiratory irrotation were confirmed in inhalation exposure tests using rats and mice, and of a description referring to confirmation of central nervous system depressions and mucosal irritation in human exposure. So it was judged as Category 3 (respiratory irritation, anesthesia action). | |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (liver) | Warning | H373: May cause damage to organs through prolonged or repeated exposure (liver) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Although the concrete case was not indicated, from description that it may affect the liver and cause a dysfunction (ICSC (J) (1997)), it was classified into Category 2 (liver). | |
10 | Aspiration hazard | Category 1 | Danger | H304: May be fatal if swallowed and enters airways |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P331: Do NOT induce vomiting. P405: Store locked up. P501: Dispose of contents/container to ... |
Since it is a hydrocarbon and the dynamic viscosity is 0.61mm2/s at 20 degrees C (calculated from the viscosity 0.4169 mPa-s and the density 0.68376g/cm3 at 20 degrees C), we classified it as Category 1. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible | - | - | - | - | Insufficient data available. |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |