GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：Hydrogen sulfide
CAS：7783-06-4
Result：
| ID: | 998 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | Gas (GHS definition) |
| 2 | Flammable gases （including chemically unstable gases） | Category 1 |
|
Danger | H220: Extremely flammable gas |
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P377: Leaking gas fire: Do not extinguish, unless leak can be stopped safely. P381: Eliminate all ignition sources if safe to do so. P403: Store in a well-ventilated place. |
Ignitable when in a mixture of 13% or less by volume in air. UNRTDG Class: 2.3, Subsidiary risks Class: 2.1 |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not classified | - | - | - | - | UNRTDG Class: 2.2, Subsidiary risks Class: 2.1 |
| 5 | Gases under pressure | Liquefied gas |
|
Warning | H280: Contains gas under pressure; may explode if heated | P410+P403: Protect from sunlight. Store in a well-ventilated place. | Critical temp: >-50degC (Partially liquid at temperatures above -50degC) |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 7 | Flammable solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 11 | Self-heating substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Gas (GHS definition) |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Gas (GHS definition) |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Although there is information on caustics to various metals (HSDB (2006)), test methods suitable for gaseous substances are not established. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 1 | Acute toxicity （Dermal） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 1 | Acute toxicity （Inhalation: Gases） | Category 2 |
|
Danger | H330: Fatal if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P284: Wear respiratory protection. P310: Immediately call a POISON CENTER or doctor/physician. P320: Specific treatment is urgent （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
It was considered as Catgory 2 based on the lower value of 444ppm. ( from rat LC50 (4 hours): 444ppm (industrial hygene academic society recommentation (2001), ACGIH (2001)), and 700mg/m3 (equivalent: 503ppm) (CICAD (2003)). |
| 1 | Acute toxicity （Inhalation: Vapours） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
| 3 | Serious eye damage/eye irritation | Category 2A |
|
Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
There is the description that irritant symptoms, such as angle conjunctivitis, punctate errosion of the cornea, watering of the eye, and photophobia, were acknowledged by contacting high hydrogen sulfide gas to the human eye directly (CICAD, 2003), and on the description that the ocular irritation was acknowledged with the hydrogen sulfide gas in the concentration of 16-32mg/m3 (10.5-21.0ppm) in several hours after exposure (EHC, 1981). So we judged that it had severe irritant property to the eye, and we classified it as Category 2A. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Although one strain has weak positive information by the reverse mutation test using the bacterial cell of in vitro, there is no data about other indices. So it cannot classify. |
| 6 | Carcinogenicity | Not classified | - | - | - | - | Since it is evaluated as I (there is no data appropriate for carcinogenicity evaluation.) in the classification of EPA, it was considered as the outside of Category. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | Although extension of childbirth time was observed in the organic formative period and the perinatal period inhalation exposure test using rats, there was no effects on fetus (CICAD, 2003). Moreover, before rat mating, in gestation and lactation periods inhalation exposure tests, although the denaturation of the minute pipe was observed in the spermary of the male of parental animals, it did not affect fertility property (CICAD, 2003). Therefore, it was judged that each influence is minimum. Moreover, increase in spontaneous abortions was observed in occupational exposure in humans, and they are also exposed to sulfur dioxide, carbon disulfide, etc. Moreover, the increase in the natural abortion in the group exposed to hydrogen sulfides exceeding 4ug/m3 over the year is not significant enough (CICAD, 2003). Therefore, since the data is inadequate for classifying about reproductive toxicity, it cannot be classified. |
| 8 | Specific target organ toxicity - Single exposure | Category 1 (central nervous system, cardiovascular system, respiratory system) |
|
Danger | H370: Causes damage to organs (central nervous system, cardiovascular system, respiratory system) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
The substance was classified as Category 1 (central nervous system, cardio-vascular system, respiratory system) based on the following reports: symptoms such as nausea, headaches, deliria, equilibrium damage, deterioration of memory, neurobehavioral changes, olfactory paralysis, unconsciousness, tremors and convulsions, and arrhythmia and elevation of blood pressure are observed after a single exposure inhalation in humans (CICAD, 2003). And unconsciousness and respiratory paralysis resulting in deaths (IRIS, 2006), and decrease in conditioned avoidance response and tissue damage to airway mucosa were observed after a single exposure inhalation at the dosage within the guidance values of Category 1 in rats, and mild irritation to nasal mucosa was observed after a single exposure inhalation in mice (CICAD, 2003). |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | Classification not possible due to lack of data |
| 10 | Aspiration hazard | Not applicable | - | - | - | - | Gas (GHS definition) |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Category 1 |
|
Warning | H400: Very toxic to aquatic life |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
It was classified into Category 1 from 96-hour LC50=0.0071mg/L of fishes (Fathead minnows (ECETOC TR91, 2003). |
| 11 | Hazardous to the aquatic environment （Long-term） | Category 1 |
|
Warning | H410: Very toxic to aquatic life with long lasting effects |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
Classified into Category 1, since acute toxicity was Category 1, and behavior in water and bioaccumulative potential are unknown. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |