GHS Classification Result

Chemical Name：pentafluoroarsorane
CAS：7784-36-3

Result：
ID: 1084
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Gas (GHS definition)
2 Flammable gases （including chemically unstable gases） Not classified - - - - Non-combustible (BGIA, GESTIS-database on hazardous substances, Accessed in May 2006)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Classification not possible - - - - No data available
5 Gases under pressure Compressed gas or Liquefied gas Warning H280: Contains gas under pressure; may explode if heated P410+P403: Protect from sunlight. Store in a well-ventilated place. Not specified whether it is a compressed or liquefied gas, due to lack of data on a critical temp, though "the boiling point is -53.2degC"(Merck, 13th, 2001)
6 Flammable liquids Not applicable - - - - Gas (GHS definition)
7 Flammable solids Not applicable - - - - Gas (GHS definition)
8 Self-reactive substances and mixtures Not applicable - - - - Gas (GHS definition)
9 Pyrophoric liquids Not applicable - - - - Gas (GHS definition)
10 Pyrophoric solids Not applicable - - - - Gas (GHS definition)
11 Self-heating substances and mixtures Not applicable - - - - Gas (GHS definition)
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - Gas (GHS definition)
13 Oxidizing liquids Not applicable - - - - Gas (GHS definition)
14 Oxidizing solids Not applicable - - - - Gas (GHS definition)
15 Organic peroxides Not applicable - - - - Gas (GHS definition)
16 Corrosive to metals Classification not possible - - - - Test methods applicable to gas substances are not available

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - No data available
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Vapours） Not applicable - - - - Gas (GHS definition)
1 Acute toxicity （Inhalation: Dusts and mists） Not applicable - - - - Gas (GHS definition)
2 Skin corrosion/irritation Category 3 - Warning H316: Causes mild skin irritation P332+P313: If skin irritation occurs: Get medical advice/attention. The knowledge of this product was not acknowledged. But from description that an inorganic arsenic compound indicates skin irritation (DFGOT 21, 2005). So it was judged that this product had mild irritation, and it was set as Category 3.
3 Serious eye damage/eye irritation Category 2B - Warning H320: Causes eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling. 		Although no findings of this product was not observed, due to the description that the fluoride shows eye irritation (ACGIH-TLV, 2005; ACGIH 7th, 2001), it was classified into Category 2B.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - It is not a deterministic conclusion (ATSDR, 2005; HSG, 1992) although there is no knowledge of the quality of a genuine article itself and skin sensitization may be shown to humans as an inorganic arsenic compound, in addition, it was presupposed that it cannot classify from the description in the humans of EHC 224 (2001) "development of the skin sensitization of inorganic arsenic is rare" since data is insufficient.
5 Germ cell mutagenicity Classification not possible - - - - Without data. In addition, arsenic and inorganic arsenic compound are classified into the germ-cell mutagenicity category 3A (equivalent for GHS Category 1B-2) in Germany DFG (MAK/BAT, 2005).
6 Carcinogenicity Category 1A Danger H350: May cause cancer P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Since arsenic and arsenic compound are categorized into the human carcinogens in IARC Suppl.7 (1987), ACGHI-TLV (2004), and MAK/BAT (2004), it was classified into Category 1A.
7 Reproductive toxicity Category 2 Warning H361: Suspected of damaging fertility or the unborn child P308+P313: IF exposed or concerned: Get medical advice/attention.
P201: Obtain special instructions before use.
P202: Do not handle until all safety precautions have been read and understood.
P281: Use personal protective equipment as required.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Although the knowledge of this product was not observed, it was considered as Category 2 based on the description related to human of EHC 224 (2001) which is Priority 1 document, about arsenic and arsenic compound, "the effect on reproduction is suggested ", and knowledge of animals "fetus toxicity and teratogenicity in dose in which maternal toxicity is observed". In addition, there is the description that "the conclusion which is inorganic arsenic is not teratogen in humans is advocated " in Catalog of teratogenic agents (2004) equivalent to Priority 1.
8 Specific target organ toxicity - Single exposure Category 1 (digestive system, cardiovascular system, nervous system, kidney, liver, respiratory system) Danger H370: Causes damage to organs (digestive system, cardiovascular system, nervous system, kidney, liver, respiratory system) P307+P311: IF exposed: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment （see ... on this label）.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Although there was no information about this substance, it was classified as Category 1 (gastrointestinal system, cardio-vascular system, nervous system, kidneys, liver, respiratory system) based on the report that in the forms of the arsenic and inorganic arsenic compounds it causes "symptoms in the gastrointestinal organs, disorders in the functions of the cardio-vascular and nervous systems, myelosuppression, alteration in the blood system and nephropathy" in humans (EHC 224 (2001)), and that based on a similar report in PIM (Poisons Information Monographs) G042 (WHO/IPCS, 1996). In addition, there are reports in ACGIH (7th, 2001) that it affects the liver, upper airways and lungs, that the inorganic arsenic dust causes irritation to the upper airways, and that the fluorides display airway irritant properties (ACGIH-TLV, 2005; ACGIH 7th, 2001).
9 Specific target organ toxicity - Repeated exposure Category 1 (digestive system, nervous system, blood system, cardiovascular system, kidney, liver, skin, respiratory system, bone) Danger H372: Cause damage to organs through prolonged or repeated exposure (digestive system, nervous system, blood system, cardiovascular system, kidney, liver, skin, respiratory system, bone) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ... 		Although the knowledge of this product was not observed, the description in the humans of EHC 224 (2001), and PIM(Poisons Information Monographs) G042 (WHO/IPCS, 1996) about arsenic and inorganic arsenics compounds, "gastrointestinal disorders, neuropathy, affect to blood systems, and abnormalities of cardiovascular systems, kidney, and liver were observed with the long term administration of inorganic arsenic. Target organ are gastrointestinal,heart,brains and kidney. The skin, marrow and peripheral nerves were also affected "and in addition, the description of the effect on the upper respiratory tract and lungs (ACGIH (7th, 2001)), and fluorides indicates the effect (fluorosis) on respiratory tract stimulative and a bone (ACGIH-TLV, 2005;ACGIH 7th, 2001). Therefore it was classified into Category 1 (digestive tract, cardiovascular systems, a nervous systems, the kidney, liver, a blood system, the skin, a respiratory system, bone)
10 Aspiration hazard Not applicable - - - - Gas (GHS definition)

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - No data available
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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