GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：arsenic pentachloride
CAS：22441-45-8
Result：
| ID: | 1090 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | Gas (GHS definition) |
| 2 | Flammable gases （including chemically unstable gases） | Not classified | - | - | - | - | Structurally, estimated non-combustible. |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Classification not possible | - | - | - | - | No data available |
| 5 | Gases under pressure | Liquefied gas |
|
Warning | H280: Contains gas under pressure; may explode if heated | P410+P403: Protect from sunlight. Store in a well-ventilated place. | Not specified whether it is a high or low pressure liquefied gas, due to lack of data on a critical temp, though it seems to be stable in a liquid state at extremely low temperature (about -50degC) |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 7 | Flammable solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 11 | Self-heating substances and mixtures | Not applicable | - | - | - | - | Gas (GHS definition) |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Gas (GHS definition) |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Gas (GHS definition) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Gas (GHS definition) |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to gas substances are not available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Gases） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Vapours） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Not applicable | - | - | - | - | Gas (GHS definition) |
| 2 | Skin corrosion/irritation | Category 2 |
|
Warning | H315: Causes skin irritation |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P362: Take off contaminated clothing and wash before reuse. |
There was no data of this product. But it was set as category 2 based on that arsenic chloride (ID 1091, Chemical Abstracts Service 7784-34-1) is classified into category 2 since it stimulates the human skin (seriously). |
| 3 | Serious eye damage/eye irritation | Category 2A |
|
Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
Although there is no data about this product, it was classified into Category 2A because arsenic chloride stimulates the hyman eye (seriously) (ID 1091, CAS 7784-34-1). Therefore, it was classified into Category 2A. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | It is not a deterministic conclusion (ATSDR, 2005; HSG, 1992) although there is no knowledge of the quality of a genuine article itself and skin sensitization may be shown to humans as an inorganic arsenic compound, in addition, it was presupposed that it cannot classify from the description in the humans of EHC 224 (2001) "development of the skin sensitization of inorganic arsenic is rare" since data is insufficient. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Without data. In addition, arsenic and inorganic arsenic compound are classified into the germ-cell mutagenicity category 3A (equivalent for GHS Category 1B-2) in Germany DFG (MAK/BAT, 2005). |
| 6 | Carcinogenicity | Category 1A |
|
Danger | H350: May cause cancer |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
Arsenic and arsenic compound are categorized into the human carcinogens in IARC Suppl.7 (1987), ACGHI-TLV (2004), and MAK/BAT (2004). So it was classified into Category 1A. |
| 7 | Reproductive toxicity | Category 2 |
|
Warning | H361: Suspected of damaging fertility or the unborn child |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
Although the knowledge of this product was not observed, it was considered as Category 2 based on the description related to human of EHC 224 (2001) which is Priority 1 document, about arsenic and arsenic compound, "the effect on reproduction is suggested ", and knowledge of animals "fetus toxicity and teratogenicity in dose in which maternal toxicity is observed". In addition, there is the description that "the conclusion which is inorganic arsenic is not teratogen in humans is advocated " in Catalog of teratogenic agents (2004) equivalent to Priority 1. |
| 8 | Specific target organ toxicity - Single exposure | Category 1 (digestive system, cardiovascular system, nervous system, kidney, liver, respiratory system) |
|
Danger | H370: Causes damage to organs (digestive system, cardiovascular system, nervous system, kidney, liver, respiratory system) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
Although there was no information about this substance, the substance was classified as Category 1 (gastrointestinal system, cardio-vascular system, nervous system, kidneys, liver, respiratory system). Based on the report that in the forms of the arsenic and inorganic arsenic compounds it causes "symptoms in the gastrointestinal organs, disorders in the functions of the cardio-vascular and nervous systems, myelosuppression, alteration in the blood system and nephropathy" in humans (EHC 224 (2001)), and based on a similar report in PIM (Poisons Information Monographs) G042 (WHO/IPCS, 1996). In addition, there is a report in ACGIH (7th, 2001) that it affects the liver, upper airways and lungs. |
| 9 | Specific target organ toxicity - Repeated exposure | Category 1 (digestive system, nervous system, blood system, cardiovascular system, kidney, liver, skin, respiratory system) |
|
Danger | H372: Cause damage to organs through prolonged or repeated exposure (digestive system, nervous system, blood system, cardiovascular system, kidney, liver, skin, respiratory system) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Although the knowledge of this product was not observed, based on the description in the humansabout arsenic and inorganic arsenics compounds, "gastrointestinal disturbances, neuropathy, affect to blood systems, and disorder of cardiovascular systems, kidney and liver were observed in the long term administration of inorganic arsenic. Target organ are gastrointestinal,heart,brains and kidney.The skin, marrow and peripheral nerves were also affected." (EHC 224 (2001), and PIM(Poisons Information Monographs) G042 (WHO/IPCS, 1996)) and the description of effect on the upper respiratory tract and lungs (ACGIH (7th, 2001)), therefore it was classified into Category 1 (digestive tract, cardiovascular systems, nervous systems, kidney, liver, blood systems, skin, respiratory system) |
| 10 | Aspiration hazard | Not applicable | - | - | - | - | Gas (GHS definition) |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
|
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
|
Reference Manual |
|
|
Definitions / Abbreviations |
|
|
Model Label by MHLW |
MHLW Website （in Japanese Only） |
|
Model SDS by MHLW |
MHLW Website （in Japanese Only） |