NITE - Chemical Management Field

GHS Classification Result

Chemical Name：ethiofencarb
CAS：29973-13-5

Result：


ID:	1137
Classifier:	Inter-ministerial Committee on GHS
Year Classified:	FY2006
Reference Manual:	GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	There are no chemical groups associated with explosive properties present in the molecules.
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Solid (GHS definition)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products
4	Oxidizing gases	Not applicable	-	-	-	-	Solid (GHS definition)
5	Gases under pressure	Not applicable	-	-	-	-	Solid (GHS definition)
6	Flammable liquids	Not applicable	-	-	-	-	Solid (GHS definition)
7	Flammable solids	Classification not possible	-	-	-	-	PM (13th, 2003) has a statement "flash point: 123degC", and it is a flammable, there is no test data, and it cannot be classified.
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9	Pyrophoric liquids	Not applicable	-	-	-	-	Solid (GHS definition)
10	Pyrophoric solids	Not classified	-	-	-	-	Flash point: 123degC (PM, 13th, 2003) and non-pyrophoric when in contact with air at a room temperature
11	Self-heating substances and mixtures	Classification not possible	-	-	-	-	Test methods applicable to solid (melting point <= 140degC) substances are not available.
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13	Oxidizing liquids	Not applicable	-	-	-	-	Solid (GHS definition)
14	Oxidizing solids	Not applicable	-	-	-	-	Organic compounds containing oxygen and the oxygen is chemically bonded only to carbon (but not to other elements).
15	Organic peroxides	Not applicable	-	-	-	-	Organic compounds containing no -0-0- structure
16	Corrosive to metals	Classification not possible	-	-	-	-	No data available

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Category 3		Danger	H301: Toxic if swallowed	P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ...	Based on the value (227 mg/kg) calculated by using the formula based on the oral LD50 values in rats, 308, 411, 499, 200 and 200mg/kg (JMPR404 (1977), RTECS (2004) and HSDB (2004)), the substance was classified as Category 3.
1	Acute toxicity （Dermal）	Category 5	-	Warning	H313: May be harmful in contact with skin	P312: Call a POISON CENTER or doctor/physician if you feel unwell.	It was set as Category 5 based on rabbit dermal LD50 = 2500mg/kg (RTECS (2004), HSDB (2004)).
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Solid (GHS definition)
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	No data available
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	Insufficient data available
2	Skin corrosion/irritation	Classification not possible	-	-	-	-	No data available
3	Serious eye damage/eye irritation	Classification not possible	-	-	-	-	No data available
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available
4	Skin sensitization	Classification not possible	-	-	-	-	No data available
5	Germ cell mutagenicity	Not classified	-	-	-	-	There is a negative result by the dominant lethal test using a mouse (JMPR404 (1977)), and other in vivo data not being found. So it carried out the outside of Category according to classification guidelines. In addition, weak positive finding is accepted in the Salmonella test (JMPR584 (1982)).
6	Carcinogenicity	Classification not possible	-	-	-	-	By the experiment using rat, it is suggested that this product has tumor promotions activity (HSDB (2004)), but there is no data of the carcinogenicity of this product, and data is insufficient. Therefore, it cannot be classified.
7	Reproductive toxicity	Not classified	-	-	-	-	In the teratogenicity study or three-generation reproduction studies using rats or rabbits, effects was not seen in reproductive potential and development, in partly, the slight effect on bone was seen (JMPR584 (1982), JMPR404 (1977)). So it carried out the outside of Category.
8	Specific target organ toxicity - Single exposure	Classification not possible	-	-	-	-	Although inhibition of cerebellar and hematological cholinesterase inhibition of the activity are observed with administration of this product in a rat (JMPR404 (1977)), there is no data which indicates the toxic effects and it cannot be classified due to insufficient data.
9	Specific target organ toxicity - Repeated exposure	Category 2 (liver)		Warning	H373: May cause damage to organs through prolonged or repeated exposure (liver)	P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ...	Since as the result in the repeated administration with dose being equivalent to Category 2 with a guidance value to the rat or the dog, the influence such as the increase in liver weights, hypertrophy of liver, or swelling of hepatocyte was observed (JMPR404 (1977)), it was classified into Category 2 (liver).
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Category 1		Warning	H400: Very toxic to aquatic life	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	It was classified into Category 1 from 48-hour LC50=0.22mg/L of Crustacea (Water fleas) (HSDB, 2004).
11	Hazardous to the aquatic environment （Long-term）	Category 1		Warning	H410: Very toxic to aquatic life with long lasting effects	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	Classified into Category 1, since acute toxicity was Category 1, supposed not rapidly degrading (BIOWIN), though supposed less bioaccumulative (log Kow=2.04 (PHYSPROP Database, 2005)).

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model Label by MHLW	MHLW Website （in Japanese Only）
Model SDS by MHLW	MHLW Website （in Japanese Only）