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GHS Classification Result

Chemical Name：dimercury dichloride
CAS：7546-30-7

Result：


ID:	1142
Classifier:	Inter-ministerial Committee on GHS
Year Classified:	FY2006
Reference Manual:	GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	There are no chemical groups associated with explosive properties present in the molecules.
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Solid (GHS definition)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products
4	Oxidizing gases	Not applicable	-	-	-	-	Solid (GHS definition)
5	Gases under pressure	Not applicable	-	-	-	-	Solid (GHS definition)
6	Flammable liquids	Not applicable	-	-	-	-	Solid (GHS definition)
7	Flammable solids	Not classified	-	-	-	-	Non-combustible (ICSC (J) (2000))
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9	Pyrophoric liquids	Not applicable	-	-	-	-	Solid (GHS definition)
10	Pyrophoric solids	Not classified	-	-	-	-	Non-combustible (ICSC (J), 2000)
11	Self-heating substances and mixtures	Not classified	-	-	-	-	Not combustible (ICSC(J) (2000))
12	Substances and mixtures which, in contact with water, emit flammable gases	Not classified	-	-	-	-	Stable to water (the water solubility is obtained)
13	Oxidizing liquids	Not applicable	-	-	-	-	Solid (GHS definition)
14	Oxidizing solids	Classification not possible	-	-	-	-	No data available
15	Organic peroxides	Not applicable	-	-	-	-	Inorganic compound
16	Corrosive to metals	Classification not possible	-	-	-	-	Test methods applicable to solid substances are not available.

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Category 3		Danger	H301: Toxic if swallowed	P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P330: Rinse mouth. P405: Store locked up. P501: Dispose of contents/container to ...	SPECIES: Rat; ENDPOINT: LD50;VALUE:210mg/kg; REFERENCE SOURCE: RTECS (2003)
1	Acute toxicity （Dermal）	Category 4		Warning	H312: Harmful in contact with skin	P302+P352: IF ON SKIN: Wash with plenty of soap and water. P280: Wear protective gloves/protective clothing/eye protection/face protection. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P322: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P501: Dispose of contents/container to ...	It is based on rat dermal LD50= 1500mg/kg (RTECS, 2003).
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Solid (GHS definition)
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	No data available
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	No data available
2	Skin corrosion/irritation	Category 2		Warning	H315: Causes skin irritation	P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P362: Take off contaminated clothing and wash before reuse.	From description (ICSC, 2000;CICAD, 50, 2003 ;DFGOT [as inorganic mercury compounds], vol.15, 2001 [as inorganic mercury compounds]) that the possibility indicates humans skin irritation. It thought that there was irritation and was set as Category 2.
3	Serious eye damage/eye irritation	Category 2B	-	Warning	H320: Causes eye irritation	P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling.	It was classified into Category 2B due to the description that it irritates to the human eye (ICSC, 2000) .
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available
4	Skin sensitization	Category 1		Warning	H317: May cause an allergic skin reaction	P302+P352: IF ON SKIN: Wash with plenty of soap and water. P333+P313: If skin irritation or rash occurs: Get medical advice/attention. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P272: Contaminated work clothing should not be allowed out of the workplace. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P501: Dispose of contents/container to ...	Since metallic mercury and inorganic mercury compound (as Hg) were made into those with skin sensitization (MAK/BAT, 2005; DFGOT, vol.15, 2001), they were set to category 1.
5	Germ cell mutagenicity	Category 2		Warning	H341: Suspected of causing genetic defects	P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ...	In ATSDR (1999), it estimated that mercury and mercury compounds induced chromosomal abnormality to the animal somatic cell in an in vivo. So they were set to Category 2.
6	Carcinogenicity	Not classified	-	-	-	-	As inorganic mercury compounds, since it is categorized as IARC Group 3 (IARC, 58, 1993) and ACGIH A4 (ACGIH-TLV, 2004), it was out of the Category.
7	Reproductive toxicity	Category 2		Warning	H361: Suspected of damaging fertility or the unborn child	P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ...	As mercury and mercury compounds or inorganic mercuries, the effect on generating (California EPA, Proposition 65 List of Chemicals, 2005) and reproductive (ACGIH-TLV, 2004) are descrived. And it was set as Category 2.
8	Specific target organ toxicity - Single exposure	Category 1 (kidney), Category 3 (respiratory tract irritation)		Danger Warning	H370: Causes damage to organs (kidney) H335: May cause respiratory irritation (respiratory tract irritation)	P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell.	Since as description in the humans in Priority 1 document, target organ as inorganic mercury compounds is the kidney (DFGOT, vol.15, 2001), and respiratory irritant was described as description in the humans in Priority 2 document (ICSC, 2000), it was considered as Category 1 (kidney) and Category 3 (respiratory irritant).
9	Specific target organ toxicity - Repeated exposure	Category 1 (central nervous system, kidney)		Danger	H372: Cause damage to organs through prolonged or repeated exposure (central nervous system, kidney)	P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ...	Because of the description in Priority 1 document that it affects central nervous system and kidneys of human body as inorganic mercury compounds or calomel-containing laxatives (ACGIH-TLV, 2004; EHC, 118, 1991; CICAD, 50, 2003), and of suggestion in Priority 2 document that it affects nervous system and a kidney (ICSC, 2000), it was classified into Category 1 (central nervous system, kidney).
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Classification not possible	-	-	-	-	No data available
11	Hazardous to the aquatic environment （Long-term）	Classification not possible	-	-	-	-	No data available.

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model Label by MHLW	MHLW Website （in Japanese Only）
Model SDS by MHLW	MHLW Website （in Japanese Only）