GHS Classification Result

Chemical Name:Copper oxychloride
CAS:1332-40-7

Result:
ID: 1296
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual (10 Feb, 2006)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Not classified - - - - Non-combustible (BGIA, GESTIS-database on hazardous substancess, Accessed in June 2006)
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups associated with explosive or self-reactive properties present in the molecule.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - Non-combustible (BGIA, GESTIS-database on hazardous substancess, Accessed in June 2006)
11 Self-heating substances and mixtures Not classified - - - - Non-combustible (BGIA, GESTIS-database on hazardous substances, accessed in June 2006)
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Stable to water (the water solubility is obtained)
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Classification not possible - - - - No data available
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available. Corrosive to metals (HSDB, 2003)

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ...
Based on the rat LD50 = 833mg/kg and 1220mg/kg in the oral administration tests (Agricultural Chemical Registration Data, 1979), the substance was classified as Category 4.
1 Acute toxicity (Dermal) Not classified - - - - The result of rat LD50 values >2000mg/kg, >2500mg/kg and >5000mg/kg of the dermal administration test was obtained (Agricultural Chemical Registration Data, 1979). But death was not observed in 5000mg/kg examination for male and female, it was set as the outside of Category.
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available
2 Skin corrosion/irritation Not classified - - - - Since irritant effects, such as erythema or dropsy, were not admitted in the skin irritation test using a female rabbits (the additional data for agricultural-chemicals applications for registration, 2006), it was set to outside of category.
3 Serious eye damage/eye irritation Category 2B - Warning H320: Causes eye irritation P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P337+P313: If eye irritation persists: Get medical advice/attention.
P264: Wash ... thoroughly after handling.
In the eye irritation tests using a doe rabbit, by the Draize method, more than 1 score of blue haze, conjunctival redness, and conjunctival edema are observed in all samples within 48 hours after application, and it recovered within 9 days (the additional data for Agricultural Chemical Registration, 2006). So it was thought that there was mild eye irritation and it was set as Category 2B.
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Not classified - - - - From the result that skin sensitization is negative (the additional data for agricultural-chemicals applications for registration, 2006) by Maximization test using a female guinea pig, it carried out the outside of Category.
5 Germ cell mutagenicity Not classified - - - - There is the negativity in the in vivo mutagenicity test using a somatic cell (micronucleus test which uses mouse bone marrow cells) (Agricultural Chemical Registration Data, 2004), and in vitro mutagenicity test (reverse mutation test using bacteria) (Agricultural Chemical Registration Data, 1989). So it is classified as the out of the Category.
6 Carcinogenicity Classification not possible - - - - No data available
7 Reproductive toxicity Classification not possible - - - - No data available
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data. In addition, there is description in ATSDR (draft, 2004) that a copper dusts stimulates respiratory tracts.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - It was presupposed that it could not be classified due to insufficient data since the toxicity to specific organ was not acknowledged in the subacute toxicity study for 90 days using rats and mice (20, 100, 500 or 3000ppm administrations) (Agricultural Chemical Registration Data, 1989).
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 1 Warning H400: Very toxic to aquatic life P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
It was classified into Category 1 from 48-hour EC50=0.105mg/L of Crustacea (Daphnia magna) (Agricultural Chemical Registration Data, 2004).
11 Hazardous to the aquatic environment (Long-term) Category 1 Warning H410: Very toxic to aquatic life with long lasting effects P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
Classified into Category 1, since acute toxicity was Category 1, and it is a metallic compound, behavior in water and bioaccumulative potential are unknown.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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