GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：lead carbonate
CAS：598-63-0
Result：
| ID: | 1317 |
| Classifier: | Inter-ministerial Committee on GHS |
| Year Classified: | FY2006 |
| Reference Manual: | GHS Classification Manual （10 Feb, 2006） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Solid (GHS definition) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Solid (GHS definition) |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 7 | Flammable solids | Not classified | - | - | - | - | Non-combustible (ICSC (J) (2001)) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups associated with explosive or self-reactive properties present in the molecule. |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 10 | Pyrophoric solids | Not classified | - | - | - | - | Non-combustible (ICSC (J), 2001) |
| 11 | Self-heating substances and mixtures | Not classified | - | - | - | - | Not combustible (ICSC(J) (2001)) |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Stable to water (the water solubility is obtained) |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 14 | Oxidizing solids | Classification not possible | - | - | - | - | No data available |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Inorganic compound |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to solid substances are not available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | No data available |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | No data available |
| 2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | No data available |
| 3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | - | No data available |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data. In addition, in ATSDR (draft, 2005), there is the description that lead induces chromosome aberration to humans, and the inorganic lead compound is classified into the germ cell mutagenicities 3A (equivalent to GHS Category 1B-2) according to MAK/BAT (2005). |
| 6 | Carcinogenicity | Category 1B |
|
Danger | H350: May cause cancer |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
There is no data of this product. But as a lead compound, it is equivalent to Category1B (inorganic lead compounds, Group 2A ) in IARC87 (2004), equivalent to Category1B-2 (Reasonably anticipated to be human carcinogens) in NTPRoC (11th, 2005), and equivalent to Category 2 (respectively B-2, A3, 2B) in IRIS (1993), ACGIH-TLV (2005), and Occupational Health Society advice (2005).Therefore, it was set as Category 1B according to Group 2A of IARC87 (2004). |
| 7 | Reproductive toxicity | Category 1A |
|
Danger | H360: May damage fertility or the unborn child |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
Since ICSC (J) (2001) of Priority 2 document has the description that "Significant reproductive toxicity is caused in humans." and ACGIH-TLV (2005) and ATSDR (draft, 2005) of Priority 1 document, etc. state that lead (inorganic lead compound) indicates reproductive toxicity in humans, it was set as Category 1A. |
| 8 | Specific target organ toxicity - Single exposure | Category 1 (central nervous system, blood, kidney) |
|
Danger | H370: Causes damage to organs (central nervous system, blood, kidney) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
Although there is description (RTECS, 2004) that the influence (spasms, nausea, vomiting) on a nervous system or an alimentary system was observed in the data (LDLo 571mg/kg) of the lowest fatal dose in human oral exposure of the procudt, it is the data near the fatal dose and treats as reference. On the other hand, in CERI Hazard Data2001-9 (2001) of Priority 1 document there is description that "in acute effects and chronic effects, almost the same symptoms were observed" as human impact of inorganic lead compound, and in ACGIH-TLV (2005), inorganic lead compounds effect on the central nervous systems, blood, and renal, so it was considered as Category 1 (a central nervous system, blood, kidney). |
| 9 | Specific target organ toxicity - Repeated exposure | Category 1 (central nervous system, blood, kidney) |
|
Danger | H372: Cause damage to organs through prolonged or repeated exposure (central nervous system, blood, kidney) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
Based on description that a human central nervous systems, blood, and the kidney are affected in repeated exposure of this product (ICSC (J), 2001), that the effect was observed on blood and the kidney in the two-year repetitive exposure test of a rat (RTECS, 2004), and that inorganic lead compounds had effects on central nervous systems, blood, and the kidney (ACGIH-TLV (2005) of Priority 1 document), it was classified into Category 1 (a central nervous systems, blood, kidney). |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Not classified | - | - | - | - | Since it was suggested from 96-hour LC50>5000000microg/L of fishes (Fathead minnows) (AQUIRE, 2003) that relevant toxicity is not indicated in the water solubility (1.1mg/L(PHYSPROP Database, 2005)) of this substance, it carried out the outside of Category. |
| 11 | Hazardous to the aquatic environment （Long-term） | Category 4 | - | - | H413: May cause long lasting harmful effects to aquatic life |
P273: Avoid release to the environment. P501: Dispose of contents/container to ... |
Classified into Category 4, since it is a metallic compound, and behavior in water is unknown, though no acute toxicity is reported within the saturated aqueous solution. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |