GHS Classification Result

Chemical Name：p-Dimethylaminobenzenediazo sulfonate
CAS：

Result：
ID: 1375
Classifier: Inter-ministerial Committee on GHS
Year Classified: FY2006
Reference Manual: GHS Classification Manual （10 Feb, 2006）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Classification not possible - - - - Classification not possible due to lack of data, though the substance contains nitrogen atoms adjacent to each other as chemical groups with explosive properties present. (No data was available with no CAS number for this substance. Refer to the sodium salt, para-Dimethylaminobenzenediazosodium sulfonate (ID No.1376, CAS No.140-56-7))
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solids Classification not possible - - - - No data available
8 Self-reactive substances and mixtures Classification not possible - - - - Although the grouping relevant to explosive (adjoining nitrogen atom) is included, the grouping relevant to autoreactive is not included. There is no data and it cannot be classified.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Classification not possible - - - - No data available
11 Self-heating substances and mixtures Classification not possible - - - - No data available
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metaloids(B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Classification not possible - - - - No data available
15 Organic peroxides Not applicable - - - - Organic compounds containing no -0-0- structure
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - No data. [Note] We could not obtain the health hazard information in the Priority 1 and 2, because this substance does not have a CAS No. When necessary, we used the findings about p-dimethylaminobenzenediazo sodium sulfonate which is the sodium salt of this substance. Refer to p-Dimethylaminobenzenediazo sodium sulfonate (ID 1376, CAS 140-56-7).
1 Acute toxicity （Dermal） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Solid (GHS definition)
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available
2 Skin corrosion/irritation Classification not possible - - - - No data available
3 Serious eye damage/eye irritation Classification not possible - - - - No data available
4 Respiratory sensitization Classification not possible - - - - No data available
4 Skin sensitization Classification not possible - - - - No data available
5 Germ cell mutagenicity Classification not possible - - - - There is no this substance data. But there is no in vivo data with p-Dimethylaminobenzenediazo sulfonate (ID 1376, CAS 140-56-7). And in in vitro mutagenicity test, there is an Ames positive (RTECS, 2003; NTP DB, 2006), MLA positives (NTP DB, 2006), CHL cell chromosome aberration positives (HSDB, 2003; RTECS, 2003), and CHO cells chromosome aberration negatives (NTP DB, 2006). There is strong response of Ames but others are not strong, and the CHO chromosome aberration test of NTP is negative. Considering these points, it is judged as there is insufficient knowledge to be Category 2, and it is treated as it cannot be classified according to the guidelines. So it cannot be classified similarly about this substance.
6 Carcinogenicity Not classified - - - - There is no data of this product. But sulfuric acid para-dimethyl aminophenydiazonium sodium (ID 1376, Chemical Abstracts Service 140-56-7) was classified into Group 3 (substance which cannot be classificationed into human carcinogenicity) in IARC (Supple.7, 1987) and carried out the outside of Category. So this product was as well set to the outside of category.
7 Reproductive toxicity Classification not possible - - - - Although there is no data on this substance, in sulfuric acid paradimethyl-aminophenyl-diazonium sodium (ID 1376, CAS: 140-56-7), fetal death and musculoskeletal effects in teratogenicity studies using female rats were reported (RTECS, 2003). However, it was judged to be unclassifiable due to insufficient data, so this substance was similarly judged to be unclassified.
8 Specific target organ toxicity - Single exposure Category 1 (kidney) Danger H370: Causes damage to organs (kidney) P307+P311: IF exposed: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P321: Specific treatment （see ... on this label）.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Although there is no data about this product, since in sulfuric acid paradimethyl aminophenyl diazonium sodium (ID 1376, CAS 140-56-7), it is supposed that in rat acute oral administration, renal tubular damages (HSDB, 2003) was observed at the dose of guidance levels of Category 1 and it was considered as Category 1 (renal). So it was similarly considered as Category 1 (renal) about the this product.
9 Specific target organ toxicity - Repeated exposure Category 2 (kidney) Warning H373: May cause damage to organs through prolonged or repeated exposure (kidney) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ... 		Although there is no data of this product, since nephropathy was observed in feeding administration for 12 months in rat at 0.10% (= an equivalent for 1000 ppm and 50 mg/kg/day) by sulfuric para-dimethylaminophenyl diazonium sodium (ID 1376, CAS 140-56-7) (HSDB, 2003) and it was equivalent to the guidance value of Category 2, and thus it was classified into Category 2 (kidney), it was similarly classified into Category 2 (kidney) on this product.
10 Aspiration hazard Classification not possible - - - - No data available

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - No data available
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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