Chemical Name:{5-[(4'-((2,6-Hydroxy-3-((2-hydroxy-5-sulfophenyl)azo)phenyl)azo)(1,1'-biphenyl)-4-yl)azo]salicylato(4-)}cuprate(2-) disodium salt; C.I. Direct Brown 95
CAS:16071-86-6
ID: | 70 |
Classifier: | Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE) |
Year Classified: | FY2007 |
Reference Manual: |
GHS Classification Manual (10 Feb, 2006) Technical Guidance Document on the GHS Classification (6 Dec, 2005) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Explosives | Not applicable | - | - | - | - | It does not contain chemical groups (aliphatic azo group) associated with explosive properties. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Solid |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
4 | Oxidizing gases | Not applicable | - | - | - | - | Solid |
5 | Gases under pressure | Not applicable | - | - | - | - | Solid |
6 | Flammable liquids | Not applicable | - | - | - | - | Solid |
7 | Flammable solids | Classification not possible | - | - | - | - | No data available. |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | It does not contain chemical groups (aliphatic azo group) associated with explosive properties or those associated with self-reactive properties. |
9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid |
10 | Pyrophoric solids | Classification not possible | - | - | - | - | No data available. |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | No data available. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | There is a product made of this substance dissolved in water. |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid |
14 | Oxidizing solids | Classification not possible | - | - | - | - | It is an organic compound containing oxygen (but not fluorine or chlorine), which is chemically bonded to sulfur. Since no test results based on standardized testing methods are available, classification is not possible. |
15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no bivalent -O-O- structure |
16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Acute toxicity (Oral) | Not classified | - | - | - | - | Since rat LD50 = 12060 mg/kg (RTECS accessed in October 2007), the substance was classified into the "Not classified" category. |
1 | Acute toxicity (Dermal) | Classification not possible | - | - | - | - | No data available. |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Since the substance is a solid, it was classified into the "Not applicable" category. |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | - | No data available. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | No data available. |
2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | No data available. |
3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | - | No data available. |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available. |
4 | Skin sensitization | Classification not possible | - | - | - | - | No data available. |
5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Both in vivo unscheduled DNA synthesis test using rats and in vitro reverse mutation test using rats gave positive results (RTECS accessed in October 2007). Since no other test results are available, classification is not possible. |
6 | Carcinogenicity | Category 1B | Danger | H350: May cause cancer |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
It is rated as "Group 2A" by the IARC (IARC Suppl. 7 (1987)) and "Group 2A" by Japan Society for Occupational Health (Recommendations of Occupational Exposure Limits 2007). Based on these ratings, the substance was classified into Category 1B. | |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available. |
8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | No data available. |
9 | Specific target organ toxicity - Repeated exposure | Category 2 (liver, bone marrow, lymphatic system) | Warning | H373: May cause damage to organs through prolonged or repeated exposure (liver, bone marrow, lymphatic system) |
P260: Do not breathe dust/fume/gas/mist/vapours/spray. P314: Get medical advice/attention if you feel unwell. P501: Dispose of contents/container to ... |
In mixed diet administration tests using rats, portal fibrosis in the liver, decreased bone marrow cells, and necrosis of lymphoid cells were noted at doses that fall under Category 2 (IARC vol. 29 (1972)). Based on these results, the substance was classified into Category 2 (liver, bone marrow, and lymphatic system). | |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Not classified | - | - | - | - | Since its 96-hour LC50 is > 180 mg/L for fathead minnow (Aquire, 2007), the substance was classified into the "Not classified" category. |
11 | Hazardous to the aquatic environment (Long-term) | Not classified | - | - | - | - | Its classification for acute toxicity is the "Not classified" category, logPow = -6.53 (SRC 2007), and it has no potential for bioaccumulation. Based on this information, the substance was classified into the "Not classified" category. |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |