Chemical Name:3,3'-Dimethoxybenzidine dihydrochloride
CAS:20325-40-0
ID: | 96 |
Classifier: | Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE) |
Year Classified: | FY2007 |
Reference Manual: |
GHS Classification Manual (10 Feb, 2006) Technical Guidance Document on the GHS Classification (6 Dec, 2005) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Solid |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
4 | Oxidizing gases | Not applicable | - | - | - | - | Solid |
5 | Gases under pressure | Not applicable | - | - | - | - | Solid |
6 | Flammable liquids | Not applicable | - | - | - | - | Solid |
7 | Flammable solids | Classification not possible | - | - | - | - | No data available. |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid |
10 | Pyrophoric solids | Classification not possible | - | - | - | - | No data available. |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | No data available. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid |
14 | Oxidizing solids | Classification not possible | - | - | - | - | Since no information on salts is available, classification is not possible. |
15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no bivalent -O-O- structure |
16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Classification not possible | - | - | - | - | No data available. |
1 | Acute toxicity (Dermal) | Classification not possible | - | - | - | - | No data available. |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Since the substance is a solid, it was classified into the "Not applicable" category. |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | - | No data available. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | No data available. |
2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | No data available. |
3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | - | No data available. |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available. |
4 | Skin sensitization | Classification not possible | - | - | - | - | No data available. See also the classification of dianisidine (CAS: 119-90-4, NITE GHS classification ID 1016). |
5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | With regard to in-vitro mutagenicity tests on 3,3'-dimethoxybenzidine dihydrochloride (CAS: 20325-40-0), both mouse lymphoma test and reverse mutation test using Salmonella typhimurium gave positive results (NTP DB, 2007; NTP TR 372, 1990). However, since no appropriate in vivo test results are available, classification is not possible. See also the classification of dianisidine (CAS: 119-90-4, NITE GHS classification ID 1016). |
6 | Carcinogenicity | Classification not possible | - | - | - | - | Salts of 3,3'-dichlorobenzidine is rated as "Carc. Cat. 2" by the EU (2007). However, since details such as grounds for the rating are unclear, classification is not possible. |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available. See also the classification of dianisidine (CAS: 119-90-4, NITE GHS classification ID 1016). |
8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | No data available. See also the classification of dianisidine (CAS: 119-90-4, NITE GHS classification ID 1016). |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | In rats given water containing 3,3'-dimethoxybenzidine dihydrochloride (CAS: 20325-40-0) showed nephropathy at doses that presumably fall under the "Not classified" category (NTP TR 372, 1990). However, since no other appropriate test results are available, classification is not possible. See also the classification of dianisidine (CAS: 119-90-4, NITE GHS classification ID 1016). |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available. See also the classification of dianisidine (CAS: 119-90-4, NITE GHS classification ID 1016). |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible | - | - | - | - | No data available. |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible | - | - | - | - | No data available. |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |