GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：dichloroacetyl chloride
CAS：79-36-7
Result：
| ID: | 20A2077 |
| Classifier: | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| Year Classified: | FY2008 |
| Reference Manual: | GHS Classification Guidance by the Japanese Government （Sep, 2008） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Liquid (room temperature) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid (room temperature) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Liquid (room temperature) |
| 6 | Flammable liquids | Category 4 | - | Warning | H227: Combustible liquid |
P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. ? No smoking. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
Its flash point of 66degC (NFPA (13th, 2002)) is equivalent to that of Category 4. |
| 7 | Flammable solid | Not applicable | - | - | - | - | Liquid (room temperature) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not classified | - | - | - | - | Its autoignition point is 585degC (ICSC (J) (1997)), which is above 70degC. |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid (room temperature) |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, AS, Se, Sn, Sb, Te, Bi, Po, At). |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | The substance is an organic compound containing not fluorine, but chlorine and oxygen, which are chemically bonded only to carbon and hydrogen. |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid (room temperature) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no bivalent -O-O- structure |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Classification not possible | - | - | - | - | Classification not possible due to lack of data. As relevant information, it is documented that its LD50 = 2460 mg/kg for rats (RTECS (2007)). However, the datum is List 3 datum, and the original test was performed many years ago (1951). |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | Classification not possible due to lack of data. As relevant information, it is documented that its LD50 = 650 microL /kg (= 995mg/kg) for rabits (RTECS (2007)). However, the datum is List 3 datum, and the original test was performed many years ago (1951). |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Liquid (room temperature) |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | Classification not possible due to lack of data. As relevant information, it is documented that its LDLo(4h) = 2000 ppm (= 12 mg/L) for rats (RTECS (2007)). However, the datum is List 3 datum, and the original test was performed many years ago (1951). |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | No data available. |
| 2 | Skin corrosion/irritation | Category 1 |
|
Danger | H314: Causes severe skin burns and eye damage |
P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting. P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. P321: Specific treatment （see ... on this label）. P363: Wash contaminated clothing before reuse. P405: Store locked up. P501: Dispose of contents/container to ... |
It has been documented that in an irritation test using rabbits in which 2 mg of the substance was applied to the skin for 24 hours, the substance was severely irritating (RTECS (2007)). Also, in cases of humans, it has been documented to be a strong irritant to skin and eyes (HSDB (2003)). Thus, the substance was classified into Category 1. |
| 3 | Serious eye damage/eye irritation | Category 1 |
|
Danger | H318: Causes serious eye damage |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P280: Wear protective gloves/protective clothing/eye protection/face protection. P310: Immediately call a POISON CENTER or doctor/physician. |
By observation 24 hours after application to rabbit eyes, degrees of irritation of most parts including the cornea were rated 10/10 (the most severe irritation) (HSDB (2003)). Also, It has been documented that in an open irritating test using rabbits in which 50 micrograms of the substance was applied to the eyes, the substance was severely irritating (RTECS (2007)). In addition, in cases of humans, it has been documented to be a strong irritant to skin and eyes (HSDB (2003)). Based on information of animals and humans, the substance was classified into Category 1. As relevant information, the substance is rated C; R35 in EU classification (EU-Annex I (accessed July 2008)). |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available. |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | Since no in vivo test data are available, classification is not possible. As relevant information, results of an Ames test using TA100 and TA98 were negative with metabolic activation and positive without metabolic activation (NTP DB (accessed July 2008)). |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | It has been documented that in an in vivo teratogenicity screening test, rats resulted in reduced fertility and increased early implantation failure (Gangolli (2nd, 1999)). However since these data are List 3 data, and no other data are available, the substance was classified into "Classification not possible" due to lack of data. |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | No data available. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | Classification not possible due to lack of data. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available. |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |