GHS Classification Result

Chemical Name:sodium methanolate; sodium methoxide
CAS:124-41-4

Result:
ID: 20A2111
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2008
Reference Manual: GHS Classification Guidance by the Japanese Government (Sep, 2008)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solid Category 1 Danger H228: Flammable solid P370+P378: In case of fire: Use ... for extinction.
P210: Keep away from heat/sparks/open flames/hot surfaces. ? No smoking.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof electrical/ventilating/lighting/.../equipment.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
The substance is flammable, but reacts vigorously with water. And predetermined tests to determine whether the substance fits in Category 1 or 2 could not be performed. And for conservative estimate, it was classified into Category 1.
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Not classified - - - - The substance fits in UNRTDG 4.2 II.
11 Self-heating substances and mixtures Category 1 Danger H251: Self-heating; may catch fire P235+P410: Keep cool. Protect from sunlight.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P407: Maintain air gap between stacks/pallets.
P413: Store bulk masses greater than ... kg/... lbs at temperatures not exceeding ... degC/... degF.
P420: Store away from other materials.
The substance fits in UNRTDG 4.2 II.
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - The substance reacts vigorously with water and results in methanol. However, since it fits in UNRTDG 4.2 II, the substance was classified into "Not classified".
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Classification not possible - - - - The substance contains oxygen, which is chemically bonded to sodium. However, there is no data available.
15 Organic peroxides Not applicable - - - - Containing no bivalent -O-O- structure in the molecule
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ...
Its four LD50 values for rats (1500, 800, 1687, and 2037 mg/kg) have been reported, and three of them are within the guidance values of Category 4 (SIDS (accessed in August 2008)).
1 Acute toxicity (Dermal) Not classified - - - - Based on the datum that in a rat test, at the dose of 2000 mg/kg, no deaths occurred (SIDS (accessed in August 2008)), the substance was classified into "Not classified" in JIS classification (Category 5 or Not classified in UN classification).
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available.
2 Skin corrosion/irritation Category 1 Danger H314: Causes severe skin burns and eye damage P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment (see ... on this label).
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to ...
Based on the report that in a rabbit test, exposure for 15 minutes caused very severe necrosis persisting after eight days (SIDS (accessed in August 2008)), the substance was classified to be corrosive.
3 Serious eye damage/eye irritation Category 1 Danger H318: Causes serious eye damage P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
Based on the report that in a rabbit test, 24 hours after application, moderate conjunctival redness, severe corneal opacity, slight oedema, and necrosis of the edges of the eye lids were seen, and after eight days, they resulted in severe necrosis, severe suppuration, and eyelids shrunken (SIDS (accessed in August 2008)), its skin corrosiveness/irritation was also classified into Category 1.
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - Since there is no in vivo test data available, classification is not possible. As relevant information, an Ames test showed negative results (SIDS (accessed in August 2008)).
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Category 3 (Narcotic effects) Warning H336: May cause drowsiness or dizziness (narcotic effects) P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P261: Avoid breathing dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P312: Call a POISON CENTER or doctor/physician if you feel unwell.
P405: Store locked up.
P501: Dispose of contents/container to ...
Based on two oral tests using rats, administration of 1000 mg/kg or lower caused narcotic condition, spastic and staggered gait, anomal posture, atonia, loss of pain reflex, and lethargy were seen (SIDS (accessed in August 2008)).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available.
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - - Since there is no appropriate data, classification is not possible.
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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