GHS Classification Result

Chemical Name：silicon tetrachloride
CAS：10026-04-7

Result：
ID: 20A2249
Classifier: Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE）
Year Classified: FY2008
Reference Manual: GHS Classification Guidance by the Japanese Government （Sep, 2008）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Liquid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Liquid (GHS definition)
5 Gases under pressure Not applicable - - - - Liquid (GHS definition)
6 Flammable liquids Not classified - - - - The substance is nonflammable (Hommel (1996)).
7 Flammable solid Not applicable - - - - Liquid (GHS definition)
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not classified - - - - The substance is nonflammable (Hommel (1996)).
10 Pyrophoric solids Not applicable - - - - Liquid (GHS definition)
11 Self-heating substances and mixtures Not classified - - - - The substance is nonflammable (Hommel (1996)).
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - It strongly reacts with water, producing silicic acid and hydrogen chloride; it does not produce flammable gases.
13 Oxidizing liquids Classification not possible - - - - No data available.
14 Oxidizing solids Not applicable - - - - Liquid (GHS definition)
15 Organic peroxides Not applicable - - - - Inorganic compound
16 Corrosive to metals Classification not possible - - - - No data available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - No data available.
1 Acute toxicity （Dermal） Classification not possible - - - - No data available.
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Liquid (GHS definition)
1 Acute toxicity （Inhalation: Vapours） Not classified - - - - Its rat LC50 value of 8000 ppm/4h (56 mg/L) (IUCLID (2000)) falls under the "Not classified" category. Since its saturated vapour concentration is <= 0.34*10^6 ppm (2398 mg/L), the test is assumed to have been conducted in vapour with almost no included mists.
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available.
2 Skin corrosion/irritation Category 1 Danger H314: Causes severe skin burns and eye damage P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment （see ... on this label）.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to ... 		The substance was found: to be corrosive in the tests using rabbits that were treated for 10 minutes (IUCLID (2000)); to be corrosive by an application of 0.5 ml for 10 minutes (IUCLID (2000)); to cause mild to moderate erythema and edema in Draize tests using rabbits that were treated for 3 minutes (IUCLID (2000)); to cause severe irritation in other Draize tests using rabbits that were treated with 500 mg for 24 hours (IUCLID (2000)). Based on these results, the substance was classified into Category 1.
3 Serious eye damage/eye irritation Category 1 Danger H318: Causes serious eye damage P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician. 		The substance was found to cause severe burns on the cornea and lids in rabbit tests, and moderate irritation in Draize tests using rabbits that were treated with 20 mg for 24 hours (IUCLID (2000)). In addition, its classification for skin irritation and corrosion is Category 1. Based on this information, the substance was classified into Category 1.
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - Classification is not possible due to lack of information such as results from in vivo mutagenicity tests and in vitro mutagenicity tests using several indices. Also, Ames tests and mouse lymphoma assays (both are in vitro mutagenicity tests) resulted in a negative outcome (IUCLID (2000)).
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Category 2 (respiratory system) Warning H371: May cause damage to organs (respiratory system) P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P405: Store locked up.
P501: Dispose of contents/container to ... 		Six plant workers who were exposed to the substance developed lung injury (IUCLID (2000)). In addition, the substance is documented to contribute to the development of RADS (reactive airway dysfunction syndrome) (HSDB(2002)). These reports indicate that the substance is to be placed in Category 1; however, since they are based on List 2 data, it was classified into Category 2 (respiratory system).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available.
10 Aspiration hazard Classification not possible - - - - The substance was classified into "Classification not possible" due to lack of sufficient information for classification.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - No data available.
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

To GHS Information