GHS Classification Result

Chemical Name：sulphur dichloride
CAS：10545-99-0

Result：
ID: 20A2253
Classifier: Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE）
Year Classified: FY2008
Reference Manual: GHS Classification Guidance by the Japanese Government （Sep, 2008）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Liquid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Liquid (GHS definition)
5 Gases under pressure Not applicable - - - - Liquid (GHS definition)
6 Flammable liquids Not classified - - - - Since its flash point is 118degC in an open system (HSDB, 2002), which is >= 110 degC, the substance was classified into "Not classified".
7 Flammable solid Not applicable - - - - Liquid (GHS definition)
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not classified - - - - Since its autoignition point is 234degC (HSDB, 2002; ICSC (J), 2007), which is higher than 70degC, the substance was classified into "Not classified".
10 Pyrophoric solids Not applicable - - - - Liquid (GHS definition)
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to liquid substances are not available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). This substance strongly reacts with water (Sax 11th, 2004), producing hydrogen chloride and sulfur dioxide. Both of these products are nonflammable gases (ICSC (J), 2007; Hommel, 1996).
13 Oxidizing liquids Classification not possible - - - - It is an inorganic compound containing halogen (Cl); classification is not possible due to lack of data.
14 Oxidizing solids Not applicable - - - - Liquid (GHS definition)
15 Organic peroxides Not applicable - - - - Inorganic substance
16 Corrosive to metals Classification not possible - - - - It is rated as UNRTDG Class 8 (UNRTDG Rev. 15, 2007); classification is not possible due to lack of data. The substance "attacks many metals in the presence of water" (ICSC (J), 2007), and "when wet it attacks steel, cast iron, aluminum, stainless steel, copper & copper alloys, & many nickel based materials" (HSDB, 2002).

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - No data available. Its documented rat LD50 values are 293 mg/kg bw (under non-stabilized condition) or 343 mg/kg bw (under the stabilized condition) (GESTIS, accessed in December 2008). This substance strongly reacts with water to produce hydrogen chloride (ICSC (J), 2007); so see the section for hydrogen chloride (CAS No. 7647-01-0: ID 567) as well.
1 Acute toxicity （Dermal） Classification not possible - - - - No data available.
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Liquid (GHS definition)
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available.
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available.
2 Skin corrosion/irritation Category 1 Danger H314: Causes severe skin burns and eye damage P301+P330+P331: IF SWALLOWED: Rinse mouth. Do NOT induce vomiting.
P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician.
P321: Specific treatment （see ... on this label）.
P363: Wash contaminated clothing before reuse.
P405: Store locked up.
P501: Dispose of contents/container to ... 		The sulfur chloride group is documented to cause irritation to the skin, eyes, and respiratory tract as a vapour; and cause severe irritation (burns) to the skin and eyes as a liquid (IUCLID, 2000). Its EU Risk Phrase is R34, corrosion (C) (EU-Annex 1, accessed in December 2008). According to the GESTIS, its major toxic effects include strong irritation to the skin and chemical burns (GESTIS, accessed in December 2008). In addition, according to the ICSC (J), its effects on the skin include redness, pain, and serious skin burns, indicating that a short-term exposure of the substance causes corrosion to the skin (ICSC (J), 2007). Based on this information, the substance was classified into Category 1.
3 Serious eye damage/eye irritation Category 1 Danger H318: Causes serious eye damage P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P310: Immediately call a POISON CENTER or doctor/physician. 		Test data for this substance are not available. However since it is known to be a skin corrosive substance, it was classified into Category 1. The sulfur chloride group is documented to cause irritation to the skin, eyes, and respiratory tract as a vapour; and cause severe irritation (burns) to the skin and eyes as a liquid (IUCLID, 2000). According to the GESTIS, its major toxic effects include strong irritation to the eyes, chemical burns and severe eye damage (GESTIS, accessed in December 2008). In addition, according to the ICSC (J), its effects on the eyes include redness, pain, and severe deep burns, indicating that a short-term exposure of the substance causes corrosion to the eyes (ICSC (J), 2007).
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - No data available.
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Category 2 (respiratory system) Warning H371: May cause damage to organs (respiratory system) P309+P311: IF exposed or if you feel unwell: Call a POISON CENTER or doctor/physician.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P405: Store locked up.
P501: Dispose of contents/container to ... 		The development of pulmonary diseases by exposure is documented to pose a risk to humans (HSDB, 2002). According to the GESTIS, its major toxic effects include irritation to the airways, chemical burns and serious lung damage (GESTIS, accessed in December 2008). In addition, according to the ICSC (J), the possible effects of a short-term exposure include corrosion of the respiratory tract and lung oedema via inhalation (ICSC (J), 2007). Based on this information, the substance was classified into Category 2 for the respiratory system through inhalation route. Also, its EU Risk Phrase is R37.
9 Specific target organ toxicity - Repeated exposure Category 2 (respiratory system) Warning H373: May cause damage to organs through prolonged or repeated exposure (respiratory system) P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P314: Get medical advice/attention if you feel unwell.
P501: Dispose of contents/container to ... 		The development of pulmonary diseases by exposure is documented to pose a risk to the humans (HSDB, 2002). According to the GESTIS, its major chronic toxic effects include irritation to the skin and airways by handling this substance (GESTIS, accessed in December 2008). Thus, the substance was classified into Category 2 (respiratory system).
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - No data available.
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

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