NITE - Chemical Management Field

GHS Classification Result

Chemical Name：Distillates (petroleum), hydrotreated light; Kerosine - unspecified
CAS：64742-47-8

Result：


ID:	20A2285
Classifier:	Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE）
Year Classified:	FY2008
Reference Manual:	GHS Classification Guidance by the Japanese Government （Sep, 2008）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive properties.
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products.
4	Oxidizing gases	Not applicable	-	-	-	-	Liquid (GHS definition)
5	Gases under pressure	Not applicable	-	-	-	-	Liquid (GHS definition)
6	Flammable liquids	Classification not possible	-	-	-	-	Since it is rated as Class 3 I, II, III by the United Nations Recommendations on the Transport of Dangerous Goods, the substance is considered to be placed in Category 1, 2 or 3. However, based on its flash point, between 68 and 74degC (ICSC (J) (2001)), which falls under the range of 60 to 93degC, its proper classification is Category 4. Moreover, according to Note 1 of the GHS document, Chapter 2.6, "Gas oils, diesel and light heating oils in the flash point range of 55degC to 75degC may be regarded as a special group for some regulatory purposes." All this information considered, the substance was classified into "Classification not possible".
7	Flammable solid	Not applicable	-	-	-	-	Liquid (GHS definition)
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive or self-reactive properties.
9	Pyrophoric liquids	Not classified	-	-	-	-	Its autoignition point is > 200degC (1013kPa) (IUCLID (2000)), which is above 70degC.
10	Pyrophoric solids	Not applicable	-	-	-	-	Liquid (GHS definition)
11	Self-heating substances and mixtures	Classification not possible	-	-	-	-	Test methods applicable to liquid substances are not available.
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	Due to deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13	Oxidizing liquids	Not applicable	-	-	-	-	Due to dissociation of oxygen from hydrocarbon through water formation, and the deposition and separation of its metal components by the catalysts during the hydrorefining process, we determined that the substance does not contain oxygen or halogen. Thus, it was classified into the "Not applicable" category.
14	Oxidizing solids	Not applicable	-	-	-	-	Liquid (GHS definition)
15	Organic peroxides	Not applicable	-	-	-	-	Due to dissociation of oxygen from hydrocarbon through water formation during the hydrorefining process, the substance is considered as an organic compound containing no bivalent -O-O- structure.
16	Corrosive to metals	Classification not possible	-	-	-	-	No data available.

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Not classified	-	-	-	-	Based on its rat LD50 of > 15000 mg/kg bw (IUCLID (2000)), the substance was classified into "Not classified".
1	Acute toxicity （Dermal）	Classification not possible	-	-	-	-	No data available.
1	Acute toxicity （Inhalation: Gases）	Not applicable	-	-	-	-	Liquid (GHS definition)
1	Acute toxicity （Inhalation: Vapours）	Classification not possible	-	-	-	-	No data available.
1	Acute toxicity （Inhalation: Dusts and mists）	Classification not possible	-	-	-	-	No data available.
2	Skin corrosion/irritation	Not classified	-	-	-	-	In the tests using rabbits (OECD TG 404) with an application duration of 4 hours and observation times of 24, 48, and 72 hours after application, the average Draize scores were 0.2 for erythema and 0.0 for edema (IUCLID (2000)). In other tests using rabbits (OECD TG 404 GLP), the average Draize scores were 1.7 for erythema and 0.7 for edema (IUCLID (2000)) or it was found to be not irritating (IUCLID (2000)). Based on these results, the substance was classified into "Not classified".
3	Serious eye damage/eye irritation	Not classified	-	-	-	-	In the tests using rabbits (GLP), the substance was found to be not irritating (IUCLID (2000)). Thus, it was classified into "Not classified".
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available.
4	Skin sensitization	Classification not possible	-	-	-	-	No data available.
5	Germ cell mutagenicity	Classification not possible	-	-	-	-	Negative results were acquired in the following tests: dominant lethal tests using mice that underwent inhalation exposure to diesel fuel (in vivo mutagenicity tests using germ cells) and micronucleus tests using bone marrow cells of mice that underwent oral administration of DMSO extract of Diesel 2 (CAS No: 64742-47-8) or cyclohexane/DMSO extract (in vivo mutagenicity tests using somatic cells) (ATSDR (1995)). However, these test results were based on extracts of test substances, and no positive results were found in any in vitro mutagenicity tests using several indices. Thus, the substance was classified into the "Classification not possible" category. As additional information, negative results were obtained in chromosomal aberration tests using bone marrow cells of rats that underwent intraperitoneal administration of kerosene (in vivo mutagenicity tests using somatic cells). However, these results cannot be confirmed as the toxicity on the treated animals or the target organ (bone marrow) was not documented (ATSDR (1995)). In in vitro mutagenicity tests (Ames tests), positive results were acquired using DMSO extract of Diesel 2 (CAS No: 64742-47-8) or cyclohexane/DMSO extract (ATSDR (1995)).
6	Carcinogenicity	Not classified	-	-	-	-	Since jet fuel including kerosene (CAS: 8008-20-6) is rated as Group 3 by the IARC (IARC vol. 45, 1989), the test substances were classified into "Not classified".
7	Reproductive toxicity	Classification not possible	-	-	-	-	Teratogenicity tests using rats that underwent kerosene inhalation exposure resulted negative (IUCLID (2000)). However, no information is available on reproductive functions and fertility of parental animals. As such, the test substance was classified into "Classification not possible".
8	Specific target organ toxicity - Single exposure	Classification not possible	-	-	-	-	No data available.
9	Specific target organ toxicity - Repeated exposure	Classification not possible	-	-	-	-	In 13-week oral administration tests using rats (OECD TG 409 GLP), no effects of administration were detected other than hepatocellular hypertrophy at the doses of 1000 mg/kg (male), 500 mg/kg (female), or 1000 mg/kg, which are higher than Category 2 guidance doses (IUCLID (2000)). Although these results indicate that the substance is to be placed in "Not classified" (oral route), they were acquired using List 2 datasets. Furthermore, no studies on other administration routes have been documented. Thus, the substance was classified into "Classification not possible". As relevant notes, although effects of alpha-2u-globlin on the kidney were detected in male rat groups administered at 100 mg/kg, these effects are considered to be specific to male rats and their toxicological significance to humans are unclear; thus, these results were not included in the evaluation.
10	Aspiration hazard	Classification not possible	-	-	-	-	No data available.

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Category 2	-	-	H401: Toxic to aquatic life	P273: Avoid release to the environment. P501: Dispose of contents/container to ...	Based on its 96h LC50 of 2.2 mg/L for fish (bluegills) (Aquire 2009), the substance was classified into Category 2.
11	Hazardous to the aquatic environment （Long-term）	Category 2		-	H411: Toxic to aquatic life with long lasting effects	P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ...	Since its classification for acute toxicity is Category 2, and there are data indicating its rapid degradability, the substance was classified into Category 2.

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model Label by MHLW	MHLW Website （in Japanese Only）
Model SDS by MHLW	MHLW Website （in Japanese Only）