GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：Fuel oil, No 4; Gasoil - unspecified
CAS：68476-31-3
Result：
| ID: | 20A2297 |
| Classifier: | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| Year Classified: | FY2008 |
| Reference Manual: | GHS Classification Guidance by the Japanese Government （Sep, 2008） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive properties. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 6 | Flammable liquids | Category 3 |
|
Warning | H226: Flammable liquid and vapour |
P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower. P370+P378: In case of fire: Use ... for extinction. P403+P235: Store in a well-ventilated place. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. ? No smoking. P233: Keep container tightly closed. P240: Ground/bond container and receiving equipment. P241: Use explosion-proof electrical/ventilating/lighting/.../equipment. P242: Use only non-sparking tools. P243: Take precautionary measures against static discharge. P280: Wear protective gloves/protective clothing/eye protection/face protection. P501: Dispose of contents/container to ... |
Its flash point is > 54degC (EHC, ATSDR) or >= 55degC (CONCAWE, ATSDR), which is in the range between 23 and 60 degC. |
| 7 | Flammable solid | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Due to dissociation of nitrogen and oxygen from hydrocarbon through the formation of ammonia and water, the saturation of unsaturated bonds and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain chemical groups associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not classified | - | - | - | - | Its flash point is 254-285degC (ACGIH) or 263degC (EHC, ATSDR). |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | Due to deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Due to dissociation of oxygen from hydrocarbon through water formation, and the deposition and separation of its metal components by the catalysts during the hydrorefining process, the substance does not contain oxygen or halogen. |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid (GHS definition) |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Due to dissociation of oxygen from hydrocarbon through water formation during the hydrorefining process, the substance is considered as an organic compound containing no bivalent -O-O- structure. |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Not classified | - | - | - | - | Its rat LD50 values are 7500 mg/kg (EHC) and 74000 mg/kg (IUCLID). Its mouse LD50 value is > 16000 mg/kg (EHC). |
| 1 | Acute toxicity （Dermal） | Not classified | - | - | - | - | Its mouse LD50 values are > 16000 mg/kg (EHC) and > 40000 mg/kg (EHC). Its rabbit LD50 value is > 5000 mg/kg (EHC). |
| 1 | Acute toxicity （Inhalation: Gases） | Classification not possible | - | - | - | - | LD50 > NOAEL. 4-hour conversion of NOAEL (6hrs*10 days) = 401.5*sqrt(60)/sqrt(4) = approx. 1500 ppmV. The substance falls under between Category 3 and "Not classified" category in the JIS classification. |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | No data available. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | LD50 > NOAEL. 4-hour conversion of NOAEL (6hrs) (ATSDR) = 2.7 mg/L*6/4 = 4.05. The substance falls under between Category 4 and "Not classified" category in the JIS classification. |
| 2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | While GLP-compliant rabbit tests found that the substance is severely irritating (IUCLID) (equivalent to Category 1 or 2), rat or other rabbit tests found that it induces no response (EHC, ACGIH) (equivalent to "Not classified" category). |
| 3 | Serious eye damage/eye irritation | Not classified | - | - | - | - | GLP-compliant rabbit tests resulted in a Draize score of 0.0 (not irritating) (IUCLID) |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | There is a description that the substance is not sensitizing (EHC); however, no data are available. |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | There is a description that the substance is not sensitizing (EHC); however, no data are available. |
| 5 | Germ cell mutagenicity | Category 2 |
|
Warning | H341: Suspected of causing genetic defects |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
In vivo mutagenicity tests using germ cells (rodent dominant lethal tests) yielded negative results (ATSDR), while in vivo mutagenicity tests using somatic cells (mammalian bone marrow chromosome aberration tests) found positive results (ATSDR). In vivo genotoxicity tests using germ cells are not available. |
| 6 | Carcinogenicity | Category 2 |
|
Warning | H351: Suspected of causing cancer |
P308+P313: IF exposed or concerned: Get medical advice/attention. P201: Obtain special instructions before use. P202: Do not handle until all safety precautions have been read and understood. P281: Use personal protective equipment as required. P405: Store locked up. P501: Dispose of contents/container to ... |
In dermally administered mice, squamous-cell, papillomas and carcinomas (EHC), or hepatocellular adenoma or carcinoma (ATSDR) were observed. The IARC lists the substance as Group 2B, and describes that marine diesel fuel is possible carcinogenic to humans. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | 13-week inhalation (mist) tests found no effects of the substance on weight and tissues of reproductive organs; however, there was no information on the developmental toxicity in offspring (ACGIH). In the tests in which test animals underwent inhalation exposure (mist) between day 6 and 15 of pregnancy, the substance is reported to have only general toxicity to parental animals, and no developmental toxicity to offspring or no effects on sex ratio; however, no information available of its toxicity on sexual functions or fertility of animals that experienced exposure before becoming pregnant (ACGIH). |
| 8 | Specific target organ toxicity - Single exposure | Category 1 (circulatory system, respiratory system) |
|
Danger | H370: Causes damage to organs (circulatory system, respiratory system) |
P307+P311: IF exposed: Call a POISON CENTER or doctor/physician. P260: Do not breathe dust/fume/gas/mist/vapours/spray. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
Inhalation exposure (vapour) was associated with development of bronchitis and ventricular tachycardia (ACGIH). Oral route exposure was associated with toxic lung diseases (ACGIH). |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | In dermal administration, a wide range of NOAEL has been reported: 2000 (ATSDR), 1000 (EHC), and < 250 mg/kg/day (ATSDR) for the skin; and 4000 (ATSDR), < 228 (ACGIH), and < 250 mg/kg/day (ATSDR) for the kidney. In inhalation administration (mist), the substance was categorized into "Not classified" for all health hazards except for the kidney, nervous system, and systemic hazards (EHC, ACGIH, ATSDR). |
| 10 | Aspiration hazard | Category 1 |
|
Danger | H304: May be fatal if swallowed and enters airways |
P301+P310: IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. P331: Do NOT induce vomiting. P405: Store locked up. P501: Dispose of contents/container to ... |
There is documentation on several cases of serious toxic lung diseases in humans (ACGIH). Its kinematic viscosity is 45-125SUS (EU-Annex 1) (conversion value: 8.6-27.0 mm2/s at 37.7degC). |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available. |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |