GHS Classification Result

Chemical Name:sulfosulfuron; 1-(4,6-dimethoxypyrimidin-2-yl)-3-(2-ethylsulfonylimidazo[1,2-a]pyridin-3-yl)sulfonylurea
CAS:141776-32-1

Result:
ID: 20A2330
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2008
Reference Manual: GHS Classification Guidance by the Japanese Government (Sep, 2008)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Solid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Solid (GHS definition)
5 Gases under pressure Not applicable - - - - Solid (GHS definition)
6 Flammable liquids Not applicable - - - - Solid (GHS definition)
7 Flammable solid Classification not possible - - - - No data available.
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not applicable - - - - Solid (GHS definition)
10 Pyrophoric solids Classification not possible - - - - No data available.
11 Self-heating substances and mixtures Not applicable - - - - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - - Solid (GHS definition)
14 Oxidizing solids Not applicable - - - - The substance contains oxygen which is chemically bonded only to carbon or hydrogen.
15 Organic peroxides Not applicable - - - - Organic compounds containing no bivalent -O-O- structure
16 Corrosive to metals Classification not possible - - - - Test methods applicable to solid substances are not available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Classification not possible - - - - No data available. According to Monsanto Company's MSDS (2004), the LD50 was found to be > 2000 mg/kg bw and no mortality occurred in mouse tests.
1 Acute toxicity (Dermal) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Solid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available.
2 Skin corrosion/irritation Classification not possible - - - - No data available. According to Monsanto Company's MSDS (2004), the substance was described as being not irritating in rabbit tests.
3 Serious eye damage/eye irritation Classification not possible - - - - No data available. According to Monsanto Company's MSDS (2004), the substance was described as being slightly irritating since recovery time was 3 days in rabbit tests.
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - No data available. According to Monsanto Company's MSDS (2004), although both in vivo and in vitro tests gave negative results, test methods are not available.
6 Carcinogenicity Classification not possible - - - - No data available. According to Monsanto Company's MSDS (2004), there were cases of the development of bladder tumors found in carcinogenicity tests using rats or mice that underwent mixed diet oral administration.
7 Reproductive toxicity Classification not possible - - - - No data available. According to Monsanto Company's MSDS (2004), no effects of the substance on offspring or parental animals were detected other than a decreased body weight seen in rats in the following studies: two-generation tests using rats, tests in which pregnant rats were administered for 6-15 days, and tests in which pregnant rabbits were administered for 7-18 days.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available. According to Monsanto Company's MSDS (2004), NOAEL for rats is 6000 mg/kg bw, as it was found in 90-day oral administration tests using rats, and NOAEL for mice is > 7000 mg/kg bw.
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Not classified - - - - Since its acute toxicity was not detected for crustaceans or fish at concentrations up to its water solubility value (Aquire 2009), the substance was classified into the "Not classified" category
11 Hazardous to the aquatic environment (Long-term) Not classified - - - - Since its potential for bioaccumulation is presumably low (LogPow = 0.99, PHYSPROP Database (2008)) and its acute toxicity was not detected for crustaceans or fish at concentrations up to its water solubility value (Aquire 2009), the substance was classified into the "Not classified" category.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


To GHS Information