GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：bis(2,6-dimethoxybenzoyl)-2,4,4-trimethylpentylphosphinoxide
CAS：145052-34-2
Result：
| ID: | 20A2332 |
| Classifier: | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| Year Classified: | FY2008 |
| Reference Manual: | GHS Classification Guidance by the Japanese Government （Sep, 2008） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecules. |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Solid (GHS definition) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Solid (GHS definition) |
| 6 | Flammable liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 7 | Flammable solid | Classification not possible | - | - | - | - | No data available. There is a description that the substance is nonflammable (NICNAS (1995)). |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
| 9 | Pyrophoric liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 10 | Pyrophoric solids | Classification not possible | - | - | - | - | No data available. There is a description that the substance is nonflammable (NICNAS (1995)). |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to solid (melting point <= 140degC) substances are not available. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not classified | - | - | - | - | Its water solubility is 0.0162 g/L at 20degC (NICNAS (1995)) and it is stable in contact with water. |
| 13 | Oxidizing liquids | Not applicable | - | - | - | - | Solid (GHS definition) |
| 14 | Oxidizing solids | Classification not possible | - | - | - | - | Organic compounds containing oxygen (but not fluorine or chlorine), which is bonded to elements other than hydrogen or carbon. However, classification is not possible due to lack of additional data. |
| 15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no bivalent -O-O- structure in the molecule |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | Test methods applicable to solid substances are not available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Classification not possible | - | - | - | - | No data available. Although its rat LD50 of > 2000 mg/kg is documented (NICNAS (1995)), classification is not possible based only on this LD50 value obtained using an unlisted dataset. |
| 1 | Acute toxicity （Dermal） | Classification not possible | - | - | - | - | No data available. Although its rabbit LD50 of > 2000 mg/kg is documented (NICNAS (1995)), classification is not possible based only on this LD50 value obtained using an unlisted dataset. |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Solid (GHS definition) |
| 1 | Acute toxicity （Inhalation: Vapours） | Classification not possible | - | - | - | - | No data available. |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | No data available. |
| 2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | No data available. Although rabbit tests found that the substance is not irritating (NICNAS (1995)), classification is not possible based only on this result obtained using unlisted datasets. |
| 3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | - | No data available. Although rabbit tests found that the substance is not irritating (NICNAS (1995)), classification is not possible based only on this result obtained using unlisted datasets. |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available. |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available. Although Draize tests using guinea pigs found that the substance is sensitizing (NICNAS (1995)), classification is not possible based only on this result obtained using unlisted datasets. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available. Although in vitro mutagenicity test results are available (NICNAS (1995)), classification is not possible based only on these results obtained using unlisted datasets. |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available. |
| 8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | No data available. |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | No data available. In 28-day oral administration toxicity tests using rats, inhibition of cholinesterase, and enlarged livers and adrenal gland were detected as effects of exposure; however, since there were no neurotoxic effects due to the inhibition of cholinesterase, these effects of exposure healed almost completely during the observational period after administration (NICNAS (1995)). Nevertheless, classification is not possible based only on these results obtained using unlisted datasets. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Category 2 | - | - | H401: Toxic to aquatic life |
P273: Avoid release to the environment. P501: Dispose of contents/container to ... |
Since its 72-hour EC50 = 1.5 mg/L for algae (Scenedesmus) (NICNAS 1995), the substance was classified into Category 2. |
| 11 | Hazardous to the aquatic environment （Long-term） | Category 2 |
|
- | H411: Toxic to aquatic life with long lasting effects |
P273: Avoid release to the environment. P391: Collect spillage. P501: Dispose of contents/container to ... |
Since its classification for acute toxicity is Category 2, and it is not rapidly degradable (degradability after 28 days = 6%: OECD TG 301B, NICNAS 1995), the substance was classified into Category 2. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |