GHS Classification Result

Chemical Name:Silicon tetrafluoride
CAS:7783-61-1

Result:
ID: 21A3556
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2009
Reference Manual: GHS Classification Guidance by the Japanese Government (March, 2009)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - Gas (GHS definition)
2 Flammable gases (including chemically unstable gases) Not classified - - - - Classified into Not classified since information is available that the substance is stable and inert to oxidation and reduction (Matheson 7th (2001)), and the substance is classified into Division 2.3, not bearing 2.1 in UNRTDG (UN1859).
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not classified - - - - Classified into Not classified since the substance is stable and inert to oxidation and reduction (Matheson 7th (2001)).
5 Gases under pressure High pressure liquefied gas Warning H280: Contains gas under pressure; may explode if heated P410+P403: Protect from sunlight. Store in a well-ventilated place. The substance is classified as "High pressure liquefied gas" since critical temperature is -14.15 degC (Matheson) between -50 degC and 65 degC.
6 Flammable liquids Not applicable - - - - Gas (GHS definition)
7 Flammable solids Not applicable - - - - Gas (GHS definition)
8 Self-reactive substances and mixtures Not applicable - - - - Gas (GHS definition)
9 Pyrophoric liquids Not applicable - - - - Gas (GHS definition)
10 Pyrophoric solids Not applicable - - - - Gas (GHS definition)
11 Self-heating substances and mixtures Not applicable - - - - Gas (GHS definition)
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - Gas (GHS definition)
13 Oxidizing liquids Not applicable - - - - Gas (GHS definition)
14 Oxidizing solids Not applicable - - - - Gas (GHS definition)
15 Organic peroxides Not applicable - - - - Gas (GHS definition)
16 Corrosive to metals Classification not possible - - - - Test methods applicable to gaseous substances are not available. Information is available that the substance decomposes forming hydrogen fluoride in presence of water and attacks many metals (ICSC 0576 (1997)).

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Classification not possible - - - - No data available. [For health hazards, refer also to hydrogen fluoride since it can react with water to produce hydrogen fluoride.]
1 Acute toxicity (Dermal) Classification not possible - - - - No data available. [For health hazards, refer also to hydrogen fluoride since the substance can react with water to produce hydrogen fluoride.]
1 Acute toxicity (Inhalation: Gases) Classification not possible - - - - Although a LC50 value of 2272 ppm for rats (RTECS (2009), original literature: Journal of Toxicological Sciences vol. 18,394 (1993)), classification was not possible since the exposure period was not clear. [For health hazards, refer also to hydrogen fluoride since it can react with water to produce hydrogen fluoride.] [Since it can react with water to produce hydrogen fluoride, refer to hydrogen fluoride for health hazards.]
1 Acute toxicity (Inhalation: Vapours) Not applicable - - - - Gas (GHS definition)
1 Acute toxicity (Inhalation: Dusts and mists) Not applicable - - - - Gas (GHS definition)
2 Skin corrosion/irritation Classification not possible - - - - No data available. Careful handling of the substance is required based of the following reports: "corrosive for the skin and eye" (ICSC (J) (1997)) and "Silicon tetrafluoride can react with water to produce hydrogen fluoride and cause irritation" (PATTY (5th, 2001)).
3 Serious eye damage/eye irritation Classification not possible - - - - No data available. As relevant information, careful handling of the substance is required based of the following reports: "corrosive for the skin and eye" (ICSC (J) (1997)) and "Silicon tetrafluoride can react with water to produce hydrogen fluoride and cause irritation" (PATTY (5th, 2001)).
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - Classification not possible due to lack of data. Although there is information from epidemiologic research where incidences of chromosome aberration and micronucleus in peripheral blood were increased in occupational exposure to both hydrofluoric acid and silicon tetrafluoride, the degree of silicon tetrafluoride contribution to the effects is uncertian.
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - Classification not possible due to lack of data. As information in RTECS (2006) in List 3, there is a report that pulmonary edema and emphysema were observed in a rat acute toxicity test (inhalation), but the exposure period or details of the test were not clear. In EHC 36 (1984), the substance is reported as a "respiratory tract irritant" and symptoms by inhalation of hydrogen fluoride (HF) are reported. Since silicon tetrafluoride can react with water to produce hydrogen fluoride, careful handling of the substance is required.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available. As relevant information, there is information of skeletal fluorosis associated with the consumption of drinking-water containing fluoride (EHC 227 (2002)). In addition, since silicon tetrafluoride can react with water to produce hydrogen fluoride, careful handling of the substance is required.
10 Aspiration hazard Not applicable - - - - Gas (GHS definition)

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - - No data available.
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - - No data available.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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