NITE - Chemical Management Field

GHS Classification Result

Chemical Name：Trifluoromethane
CAS：75-46-7

Result：


ID:	21A3560
Classifier:	Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE）
Year Classified:	FY2009
Reference Manual:	GHS Classification Guidance by the Japanese Government （March, 2009）

PHYSICAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Explosives	Not applicable	-	-	-	-	Gas (GHS definition)
2	Flammable gases （including chemically unstable gases）	Not applicable	-	-	-	-	Not combustible gas (Merck (14th, 2006))
3	Aerosols	Not applicable	-	-	-	-	Not aerosol products.
4	Oxidizing gases	Not classified	-	-	-	-	Classified into Not classified since the substance is classified into Division 2.2 in UNRTDG (UN1984, 3136) and Subsidiary risk is not 5.1, further ERG is not 122 (Gases - Oxidizing).
5	Gases under pressure	High pressure liquefied gas		Warning	H280: Contains gas under pressure; may explode if heated	P410+P403: Protect from sunlight. Store in a well-ventilated place.	The substance is classified as High pressure liquefied gas since critical temperature is 26.3 degC (Ullmanns (E) (6th, 2003)) between -50 degC and 65 degC.
6	Flammable liquids	Not applicable	-	-	-	-	Gas (GHS definition)
7	Flammable solids	Not applicable	-	-	-	-	Gas (GHS definition)
8	Self-reactive substances and mixtures	Not applicable	-	-	-	-	Gas (GHS definition)
9	Pyrophoric liquids	Not applicable	-	-	-	-	Gas (GHS definition)
10	Pyrophoric solids	Not applicable	-	-	-	-	Gas (GHS definition)
11	Self-heating substances and mixtures	Not applicable	-	-	-	-	Gas (GHS definition)
12	Substances and mixtures which, in contact with water, emit flammable gases	Not applicable	-	-	-	-	Gas (GHS definition)
13	Oxidizing liquids	Not applicable	-	-	-	-	Gas (GHS definition)
14	Oxidizing solids	Not applicable	-	-	-	-	Gas (GHS definition)
15	Organic peroxides	Not applicable	-	-	-	-	Gas (GHS definition)
16	Corrosive to metals	Classification not possible	-	-	-	-	Test methods applicable to gaseous substances are not available.

HEALTH HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
1	Acute toxicity （Oral）	Classification not possible	-	-	-	-	No data available.
1	Acute toxicity （Dermal）	Classification not possible	-	-	-	-	No data available.
1	Acute toxicity （Inhalation: Gases）	Classification not possible	-	-	-	-	Although no mortality were observed in guinea pigs after exposure to gas mixtures of the substance (50% with 50% air or 80 % with 20% oxygen) (GESTIS (access on Aug. 2009)), classification was not possible since original literature and an exposure period are not clear.
1	Acute toxicity （Inhalation: Vapours）	Not applicable	-	-	-	-	Gas (GHS definition)
1	Acute toxicity （Inhalation: Dusts and mists）	Not applicable	-	-	-	-	Gas (GHS definition)
2	Skin corrosion/irritation	Classification not possible	-	-	-	-	No data available.
3	Serious eye damage/eye irritation	Classification not possible	-	-	-	-	No data available.
4	Respiratory sensitization	Classification not possible	-	-	-	-	No data available.
4	Skin sensitization	Classification not possible	-	-	-	-	No data available.
5	Germ cell mutagenicity	Classification not possible	-	-	-	-	No data available.
6	Carcinogenicity	Classification not possible	-	-	-	-	No data available.
7	Reproductive toxicity	Classification not possible	-	-	-	-	No data available.
8	Specific target organ toxicity - Single exposure	Category 3 （Narcotic effects）		Warning	H336: May cause drowsiness or dizziness (narcotic effects)	P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ...	Based on a report of a narcotic effect at high concentration (HSDB (2003)) and a report that following inhalation exposure to concentrations between 10 and 60%, 1 of 5 volunteers showed anesthetic effects, the substance was classified into Category 3 (narcotic effects). As relevant information, human exposure experience indicate that high vapour concentration may cause confusion, pulmonary irritation, tremors and rarely coma, but these effects are generally transient and without late sequelae (HSDB (2003)). Furthermore, inhalation of high concentrations is associated with the development of refractory ventricular dysrhythmias and sudden death, believed to be secondary to hypoxia or myocardial sensitization (HSDB (2003)).
9	Specific target organ toxicity - Repeated exposure	Classification not possible	-	-	-	-	No data available.
10	Aspiration hazard	Not applicable	-	-	-	-	Gas (GHS definition)

ENVIRONMENTAL HAZARDS

Hazard class		Classification	Symbol	Signal word	Hazard statement	Precautionary statement	Rationale for the classification
11	Hazardous to the aquatic environment （Acute）	Classification not possible	-	-	-	-	No data available.
11	Hazardous to the aquatic environment （Long-term）	Classification not possible	-	-	-	-	No data available.

NOTE:

* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：

Reference Manual
Definitions / Abbreviations
Model Label by MHLW	MHLW Website （in Japanese Only）
Model SDS by MHLW	MHLW Website （in Japanese Only）