GHS Classification Result

Chemical Name：Propylene trimer
CAS：13987-01-4

Result：
ID: 21A3638
Classifier: Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE）
Year Classified: FY2009
Reference Manual: GHS Classification Guidance by the Japanese Government （March, 2009）

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases （including chemically unstable gases） Not applicable - - - - Liquid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products
4 Oxidizing gases Not applicable - - - - Liquid (GHS definition)
5 Gases under pressure Not applicable - - - - Liquid (GHS definition)
6 Flammable liquids Category 2 Danger H225: Highly flammable liquid and vapour P303+P361+P353: IF ON SKIN （or hair）: Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P370+P378: In case of fire: Use ... for extinction.
P403+P235: Store in a well-ventilated place. Keep cool.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof electrical/ventilating/lighting/.../equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ... 		Classified into Category 2 since flash point 24 degC (open-cup) is <23 degC (closed-cup) and initial boiling point 133 - 142 degC is >35 degC (NFPA (13th, 2006)), further the substance is classified into Class 3, PG II, III in UNRTDG (UN2057). However, classified into Category 3 from PG III in UNRTDG (UN2057), therefore, tests should be conducted by products to establish the classification.
7 Flammable solids Not applicable - - - - Liquid (GHS definition)
8 Self-reactive substances and mixtures Type G - - - - Classified into Type G since the substance does not fall into upper Division 4.1 (Self-reactive substances and mixtures) from which it is classified into Class 3 in UNRTDG (UN2057) though there are chemical groups (unsaturated bond) present in the molecule associated with self-reactive properties.
9 Pyrophoric liquids Not classified - - - - Classified into Not classified since auto-ignition point is 260 degC (Hommel (1996)) exceeding 70 degC.
10 Pyrophoric solids Not applicable - - - - Liquid (GHS definition)
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to liquid substances are not available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - - Containing no oxygen, fluorine or chlorine in the molecule
14 Oxidizing solids Not applicable - - - - Liquid (GHS definition)
15 Organic peroxides Not applicable - - - - Organic compounds containing no bivalent -O-O- structure
16 Corrosive to metals Classification not possible - - - - No data available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity （Oral） Classification not possible - - - - No data available. The LD50 values of the analogs for rats are as follows; CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich): >2332 mg/kg (SIDS (2004)), CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich): >2350 mg/kg (IUCLID (2000)), and CAS No. 27215-95-8 (Nonene): 2100 mg/kg (IUCLID (2000)). All analogs correspond to "Not classified" in JIS Classification (correspond to Category 5 in GHS classification).
1 Acute toxicity （Dermal） Classification not possible - - - - No data available. The LD50 values of the analogs for rabbits are as follows; CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich): > 2332 mg/kg (SIDS (2004)), CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich): >2350 mg/kg (IUCLID (2000)), and CAS No. 27215-95-8 (Nonene): 5000 mg/kg (IUCLID (2000)). All analogs correspond to "Not classified" in JIS Classification (correspond to Category 5 in GHS classification).
1 Acute toxicity （Inhalation: Gases） Not applicable - - - - Liquid (GHS definition)
1 Acute toxicity （Inhalation: Vapours） Classification not possible - - - - No data available. LC50 values of the analogs for rats are as follows; CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich): >13.6 mg/L (vapour) (4-hour equivalence) (SIDS (2004)) and CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich): 22.7 mg/L (IUCLID (2000)). The analogs correspond to Category 4 or "Not classified".
1 Acute toxicity （Inhalation: Dusts and mists） Classification not possible - - - - No data available.
2 Skin corrosion/irritation Classification not possible - - - - No data available. As relevant information, there are reports that in a rabbit 24-hour exposure occlusive dressing irritation test, the analogs, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich) and CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich) induced slight erythema along with desquamation (SIDS (2004), IUCLID (2000)). These analogs correspond to "Not classified" in JIS Classification (correspond to Category 3 in GHS classification).
3 Serious eye damage/eye irritation Classification not possible - - - - No data available. As relevant information, there are reports that in a rabbit eye irritation test (Draize method), the analog, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich) induced "mild conjunctival irritation cleared by 24-hour" (SIDS (2004)) and another analog, CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich) was estimated to be "slightly irritating " (IUCLID (2000)). These analogs correspond to "Not classified".
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available. For the analogs, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich) and CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich), negative results in a guinea pig skin sensitization test (Maximization test, OECD TG406) were reported (IUCLID (2000)).
5 Germ cell mutagenicity Classification not possible - - - - No data available. As relevant information, the analogs, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich) and CAS No. 97593-01-6 (Alkenes, C8-10, C9-rich) correspond to "Not classified" based on negative results in mouse bone marrow micronucleus tests (in vivo somatic cell mutagenicity tests, GLP) (SIDS (2004), IUCLID (2000)). In addition, the results of bacteria reverse mutation tests (in vitro mutagenicity tests, GLP) of these analogs were also negative (SIDS (2004), IUCLID (2000)).
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available. As relevant information, for the analogs, CAS No. 68526-55-6 (Alkenes, C8-10, C9-rich), nasal discharge and congested adrenal glands were observed at higher dose levels (73.5 mg/kg and higher) in a rat oral test (SIDS (2004)); atonia was observed at a dose level of 73.8 mg/kg in a rabbit dermal test (SIDS (2004)); and in a inhalation test with mice, rats and guinea pigs, at a dose level of 11.1 mg/L, mice exhibited labored breathing patterns, rats exhibited limb ataxia and general lethargic behavior and guinea pigs showed slight tremors (SIDS (2004)). Since the respiratory system, central nervous system and adrenal gland are regarded as target organs, the substance was classified into Category 1 (nasal cavity, adrenal gland) and Category 2 (respiratory system, central nervous system).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available.
10 Aspiration hazard Classification not possible - - - - No data available. As relevant information, for the analog, nonene, there are reports of "an aspiration hazard when ingested" and "irritating to skin, eye, nose and throat, and anesthetic in high concentration" (PATTY (5th, 2001)). In addition, C6-C18 alkenes were assessed for aspiration hazard in an animal test using rats. All animals exposed to C8 to C14 died within 24-hour and the affected animals showed chemical pneumonitis. The report concluded that there is a significant aspiration hazard with C6 to C14 alkenes (SIDS (2004)).

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment （Acute） Classification not possible - - - - Classification not possible due to lack of data.
11 Hazardous to the aquatic environment （Long-term） Classification not possible - - - - Classification not possible due to lack of data.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference：
Reference Manual
Definitions / Abbreviations
Model Label by MHLW

 MHLW Website （in Japanese Only）
Model SDS by MHLW

 MHLW Website （in Japanese Only）

To GHS Information