GHS Classification Result

Chemical Name:Propylene tetramer
CAS:6842-15-5

Result:
ID: 21A3653
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2009
Reference Manual: GHS Classification Guidance by the Japanese Government (March, 2009)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecules.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Liquid (GHS definition)
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Liquid (GHS definition)
5 Gases under pressure Not applicable - - - - Liquid (GHS definition)
6 Flammable liquids Category 3 Warning H226: Flammable liquid and vapour P303+P361+P353: IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower.
P370+P378: In case of fire: Use ... for extinction.
P403+P235: Store in a well-ventilated place. Keep cool.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P233: Keep container tightly closed.
P240: Ground/bond container and receiving equipment.
P241: Use explosion-proof electrical/ventilating/lighting/.../equipment.
P242: Use only non-sparking tools.
P243: Take precautionary measures against static discharge.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ...
Classified into Category 3 since flash point 49 degC (Weiss (2nd, 1986)) is >23 degC and <60 degC. The substance is classified into Class 3, PG III in UNRTDG (UN2850).
7 Flammable solids Not applicable - - - - Liquid (GHS definition)
8 Self-reactive substances and mixtures Type G - - - - Classified into Type G since the substance is considered not to fall into upper Division 4.1 (Self-reactive substances and mixtures) from which it is classified into Class 3 in UNRTDG (UN2850) though there are chemical groups (unsaturated bond) present in the molecule associated with self-reactive properties.
9 Pyrophoric liquids Not classified - - - - Classified into Not classified since auto-ignition point is 255 degC (Hommel (1996)) exceeding 70 degC.
10 Pyrophoric solids Not applicable - - - - Liquid (GHS definition)
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to liquid substances are not available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - - The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - - Containing no oxygen, fluorine or chlorine in the molecule
14 Oxidizing solids Not applicable - - - - Liquid (GHS definition)
15 Organic peroxides Not applicable - - - - Organic compounds containing no bivalent -O-O- structure
16 Corrosive to metals Classification not possible - - - - No data available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Not classified - - - - Based on a LD50 value of >2000 mg/kg bw (approximately 5000 mg/kg) for rats ("Toxicity Testing Reports of Environmental Chemicals" (Chemicals Investigation Promoting Council) (access on Oct. 2009)), the substance was classified as "Not classified" in JIS Classification (correspond to Category 5 in GHS classification).
1 Acute toxicity (Dermal) Classification not possible - - - - Classification not possible due to lack of data. As relevant information, a LD50 value is >2 g/kg for rats (RTECS (1997)).
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Liquid (GHS definition)
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - - Classification not possible due to lack of data. As relevant information, a LC50 value is >735 ppm (5.06 mg/L) for rats (RTECS (1997)).
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available. The analog, C10-13 Internal Olefins, corresponds to Category 4 or "Not classified" based on a LC50 value of >2.1 mg/L (mist) for rats (SIDS (2004)).
2 Skin corrosion/irritation Classification not possible - - - - No data available. As relevant information, the analog, 1-Dodecene (CAS No. 112-41-4), corresponds to Category 2 based on the report that the skin primary irritation index was 4.67 and the mean 24 - 72-hour scores for erythema and edema were 2.2 and 2.4, respectively, in a rabbit skin irritation test (OECD TG404 (GLP)) (SIDS (2004)).
3 Serious eye damage/eye irritation Classification not possible - - - - No data available. As relevant information, the analog, 1-Dodecene (CAS No. 112-41-4), corresponds to "Not classified" based on the report that irritating was observed in the cornea and conjunctiva at 24-hour but all scores at 48 and 72-hour were zero in a rabbit eye irritation test (Draize method) (SIDS (2004)).
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available. For the analogs, C10-13 Alpha Olefins (mixture of CAS No. 872-05-9, CAS No. 821-95-4, CAS No. 112-41-4 and CAS No. 2437-56-1) and C12-16 Alpha Olefin Fraction (mixture of linear 1-dodecene (CAS No. 112-41-4), 1-tetradecene (CAS No. 1120-36-1) and 1-hexadecene (CAS No. 629-73-2), negative results in a guinea pig skin sensitization test (Maximization test) were reported (SIDS (2004)).
5 Germ cell mutagenicity Classification not possible - - - - Classification not possible due to lack of data from in vivo mutagenicity tests. From in vitro mutagenicity tests, there are reports of a negative bacteria reverse mutation test and a negative Chinese hamster culture cell chromosomal aberration test (SIDS (2004)).
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - Classification not possible due to lack of data. As relevant information, there is a report of effects on the sense organs (especially eye) in a rat oral test (unknown dose level) (Journal of the American College of Toxicology, Part B. vol. 1, p. 741, 1992). For the analogs, there are the following reports (SIDS (2004)). For CAS No. 68526-58-9 (Alkenes, C11-13, C12 rich) and CAS No. 112-41-4 (1-Dodecene), there were no toxic findings (grossly and histologically) in a rat oral test (7.74 g/kg and 10 g/kg). For CAS No. 68526-58-9 (Alkenes, C11-13, C12 rich), increases in locomotor activity (all animal species) and lacrimation (rats and guinea pigs) were observed in a inhalation test with mice, rats and guinea pigs (4.4 mg/L (639 ppm), 6hr). For C10-13 Internal Olefins (Shop Olefins 103 PQ 11), lacrimation and increased salivation were observed in a rat inhalation test (mist, >2.1 mg/L (>305 ppm)). For C12-16 Alpha Olefin Fraction (GULFTENE 12-16), there was no visceral or systemic toxicity in a rabbit dermal test (10 g/kg, 24-hour).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available. For the analog, C12-16 Alpha Olefin Fraction, depressed body weight gain, changes in organ-to-body weight ratios and changes in organ-to-brain weight ratios at a dose level within the guidance value range for Category 2 (200 mg/kg/day, 90-day) were reported in a rat 2-week (9 times applications) dermal test (SIDS (2004)).
10 Aspiration hazard Classification not possible - - - - No data available. As relevant information, for the analog, dodecene, there is a report of "may present an aspiration hazard when ingested" (PATTY (5th, 2001)). In addition, C6-C18 alkenes were assessed for aspiration hazard in an animal test using rats. All animals exposed to C8 to C14 died within 24-hour and the affected animals showed chemical pneumonitis. The report concluded that there is a significant aspiration hazard with C6 to C14 alkenes (SIDS (2004)).

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 1 Warning H400: Very toxic to aquatic life P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
Classified into Category 1 from its 48h-EC50 = 0.015 mg/L for Crustacea (Daphnia magna) (Test for the Ecological Effect of Chemical Substances (Ministry of the Environment), 2002).
11 Hazardous to the aquatic environment (Long-term) Category 1 Warning H410: Very toxic to aquatic life with long lasting effects P273: Avoid release to the environment.
P391: Collect spillage.
P501: Dispose of contents/container to ...
Classified into Category 1 since its acute toxicity is Category 1 and it is not rapidly degradable (Biodegradation and Bioconcentration of Existing Chemical Substances under the Chemical Substances Control Law, 1988).


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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