GHS Classification Result
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：tert-Butyl peracetate
CAS：107-71-1
Result：
| ID: | 21A3654 |
| Classifier: | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| Year Classified: | FY2009 |
| Reference Manual: | GHS Classification Guidance by the Japanese Government （March, 2009） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | Division 1.1 |
|
Danger | H201: Explosive; mass explosion hazard |
P370+P380: In case of fire: Evacuate area. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P230: Keep wetted with ... P240: Ground/bond container and receiving equipment. P250: Do not subject to grinding/shock/.../friction. P280: Wear protective gloves/protective clothing/eye protection/face protection. P372: Explosion risk in case of fire. P374: Fight fire with normal precautions from a reasonable distance. P401: Store ... P501: Dispose of contents/container to ... |
Classified into Division 1.1 since the substance contains chemical groups (peroxides) associated with explosive properties present in the molecules and it is mentioned in literature that pure substance is shocksensitive and detonable ("The pure ester is also shocksensitive and denotable, but the commercial 75% solutions are not." (Bretherick (7th, 2007))). |
| 2 | Flammable gases （including chemically unstable gases） | Not applicable | - | - | - | - | Liquid at room temperature (Chapman (Ver. 17.1, 2009)) |
| 3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
| 4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid at room temperature (Chapman (Ver. 17.1, 2009)) |
| 5 | Gases under pressure | Not applicable | - | - | - | - | Liquid at room temperature (Chapman (Ver. 17.1, 2009)) |
| 6 | Flammable liquids | Classification not possible | - | - | - | - | Classification is not possible since data on flash point of commercial products vary with each solvent (Hommel (1996)). |
| 7 | Flammable solids | Not applicable | - | - | - | - | Liquid at room temperature (Chapman (Ver. 17.1, 2009)) |
| 8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | Organic peroxides |
| 9 | Pyrophoric liquids | Not classified | - | - | - | - | Auto-ignition point is >360 degC (Chemical Risk Information Platform (CHRIP) (access on Oct. 2009)) exceeding 70 degC. |
| 10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid at room temperature (Chapman (Ver. 17.1, 2009)) |
| 11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available. |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
| 13 | Oxidizing liquids | Classification not possible | - | - | - | - | No data available. |
| 14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid at room temperature (Chapman (Ver. 17.1, 2009)) |
| 15 | Organic peroxides | Type A |
|
Danger | H240: Heating may cause an explosion |
P411+P235: Store at temperatures not exceeding ... degC/... degF. Keep cool. P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking. P220: Keep/Store away from clothing/.../combustible materials. P234: Keep only in original container. P280: Wear protective gloves/protective clothing/eye protection/face protection. P410: Protect from sunlight. P420: Store away from other materials. P501: Dispose of contents/container to ... |
Commercial products are the solution using benzene, dibutyl phthalate or petroleum as the solvent (Hommel (1996)). Pure substance and products with solvent content of <23% can not be transported and are estimated to be "Type A". Products with solvent content of 23 - 48%, 48 - 68% and >=60% are UN3101(Type B), UN3103 (Type C) and UN3109 (Type F), respectively and are allowed to transport (UNRTDG 2.5.3.2.4). |
| 16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | Not classified | - | - | - | - | Based on a LD50 value of 2562 mg/kg bw for rats (DFGOT vol. 3 (1992)), the substance was classified into "Not classified" in JIS Classification (correspond to Category 5 in GHS classification). |
| 1 | Acute toxicity （Dermal） | Not classified | - | - | - | - | Based on a LD50 value of 4757 mg/kg bw for rats (DFGOT vol. 3 (1992)), the substance was classified as "Not classified" in JIS Classification (correspond to Category 5 in GHS classification). |
| 1 | Acute toxicity （Inhalation: Gases） | Not applicable | - | - | - | - | Liquid (room temperature) |
| 1 | Acute toxicity （Inhalation: Vapours） | Category 3 |
|
Danger | H331: Toxic if inhaled |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P311: Call a POISON CENTER or doctor/physician. P321: Specific treatment （see ... on this label）. P405: Store locked up. P501: Dispose of contents/container to ... |
Based on a LC50 value of 1128 ppm/4h for rats (PATTY (5th, 2001)), the substance was classified into Category 3. Since the test concentration was lower than 90% of saturated vapour pressure concentration, the classification criteria for gas was adopted |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | Classification not possible | - | - | - | - | No data available. |
| 2 | Skin corrosion/irritation | Not classified | - | - | - | - | Based on a result of "no irritation" to skin in a rabbit test (DFGOT vol. 3 (1992)) and a report that a 75% solution in odorless mineral spirits was "slight irritant" in a primary skin irritation test (PATTY (5th, 2001)), the substance was classified as "Not classified" in JIS Classification (correspond to Category 3 or "Not classified" in GHS classification). |
| 3 | Serious eye damage/eye irritation | Category 2 |
|
Warning | H319: Causes serious eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. |
Based on a report of "irritation " in a rabbit test (DFGOT vol. 3 (1992)), the substance was classified into Category 2. As relevant information, there is a result of "moderate" in a irritation test where 100 mg of the substance was applied to rabbit eyes and the eyes were washed with water following a1-minute exposure (RTECS (2008)). |
| 4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available. |
| 4 | Skin sensitization | Classification not possible | - | - | - | - | No data available. |
| 5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available. |
| 6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available. |
| 7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available. |
| 8 | Specific target organ toxicity - Single exposure | Category 3 （Respiratory tract irritation, Narcotic effects） |
|
Warning | H335: May cause respiratory irritation (respiratory tract irritation, narcotic effects) |
P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing. P403+P233: Store in a well-ventilated place. Keep container tightly closed. P261: Avoid breathing dust/fume/gas/mist/vapours/spray. P271: Use only outdoors or in a well-ventilated area. P312: Call a POISON CENTER or doctor/physician if you feel unwell. P405: Store locked up. P501: Dispose of contents/container to ... |
In a rat 8-hour inhalation test, rats exhibited initial dyspnea (and temporary restlessness at high dose group), followed by crouching position, lacrimation, nasal discharge, slight anesthetized state and labored respiration. Based on reports of dyspnea, lacrimation and nasal discharge, the substance was classified into Category 3 (respiratory tract irritation). Additionally, based on a report of slight anesthetized state, the substance was classified into Category 3 (narcotic effects). |
| 9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | No data available. |
| 10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available. |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | Classification not possible | - | - | - | - | No data available. |
| 11 | Hazardous to the aquatic environment （Long-term） | Classification not possible | - | - | - | - | No data available. |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |