GHS Classification Result （Revision of the past classification result）
PHYSICAL HAZARDS
HEALTH HAZARDS
ENVIRONMENTAL HAZARDS
NOTE:
Reference：
Chemical Name：2-Hexyloxyethanol
CAS：112-25-4
Result：
| ID: | 21C0010 |
| Classifier: | Ministry of Health, Labour and Welfare （MHLW）, Ministry of the Environment （MOE） |
| Year Classified: | FY2009 |
| Reference Manual: | GHS Classification Guidance by the Japanese Government （March, 2009） |
PHYSICAL HAZARDS
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Explosives | - | - | - | - | - | − |
| 2 | Flammable gases （including chemically unstable gases） | - | - | - | - | - | − |
| 3 | Aerosols | - | - | - | - | - | − |
| 4 | Oxidizing gases | - | - | - | - | - | − |
| 5 | Gases under pressure | - | - | - | - | - | − |
| 6 | Flammable liquids | - | - | - | - | - | − |
| 7 | Flammable solids | - | - | - | - | - | − |
| 8 | Self-reactive substances and mixtures | - | - | - | - | - | − |
| 9 | Pyrophoric liquids | - | - | - | - | - | − |
| 10 | Pyrophoric solids | - | - | - | - | - | − |
| 11 | Self-heating substances and mixtures | - | - | - | - | - | − |
| 12 | Substances and mixtures which, in contact with water, emit flammable gases | - | - | - | - | - | − |
| 13 | Oxidizing liquids | - | - | - | - | - | − |
| 14 | Oxidizing solids | - | - | - | - | - | − |
| 15 | Organic peroxides | - | - | - | - | - | − |
| 16 | Corrosive to metals | - | - | - | - | - | − |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 1 | Acute toxicity （Oral） | - | - | - | - | - | − |
| 1 | Acute toxicity （Dermal） | - | - | - | - | - | − |
| 1 | Acute toxicity （Inhalation: Gases） | - | - | - | - | - | − |
| 1 | Acute toxicity （Inhalation: Vapours） | - | - | - | - | - | − |
| 1 | Acute toxicity （Inhalation: Dusts and mists） | - | - | - | - | - | − |
| 2 | Skin corrosion/irritation | Category 2 |
|
Warning | H315: Causes skin irritation |
P302+P352: IF ON SKIN: Wash with plenty of soap and water. P332+P313: If skin irritation occurs: Get medical advice/attention. P264: Wash ... thoroughly after handling. P280: Wear protective gloves/protective clothing/eye protection/face protection. P321: Specific treatment （see ... on this label）. P362: Take off contaminated clothing and wash before reuse. |
In a test (Directive 84/449/EEC, B4) where the substance (stock solution) was applied to the skin of 6 rabbits for 4-hour, skin reactions developed within 1-hour after application (average erythema and edema Draize scores were 1.3 and 1.7, respectively). The effects were resolved between 2 to 7 days. 3 rabbits showed necrosis at the application site between Days 1 and 7, desquamation was found in 4 animals on Day 7 (SIDS (access on Aug. 2008)). The results indicated that the erythema, edema and necrosis which developed following application showed recovery or a trend of recovery within 7 days. Based on the data, the substance was classified into Category 2. In another rabbit test, there is a result of "not irritating" (SIDS (access on Aug. 2008)). In EU classification, the substance is classified into R34 (EU-Annex I (access on Aug. 2008)). |
| 3 | Serious eye damage/eye irritation | Category 2B | - | Warning | H320: Causes eye irritation |
P305+P351+P338: IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing. P337+P313: If eye irritation persists: Get medical advice/attention. P264: Wash ... thoroughly after handling. |
In a rabbit eye irritation test, reversible chemosis (Draize scores of 2 - 3), iritis (Draize score of 1) and corneal opacity (Draize score of 1) were observed. No injury was observed in any of the animals after 7 days (SIDS (access on Aug. 2008)). Based on the report, the substance was classified into Category 2B. |
| 4 | Respiratory sensitization | - | - | - | - | - | − |
| 4 | Skin sensitization | - | - | - | - | - | − |
| 5 | Germ cell mutagenicity | - | - | - | - | - | − |
| 6 | Carcinogenicity | - | - | - | - | - | − |
| 7 | Reproductive toxicity | - | - | - | - | - | − |
| 8 | Specific target organ toxicity - Single exposure | - | - | - | - | - | − |
| 9 | Specific target organ toxicity - Repeated exposure | - | - | - | - | - | − |
| 10 | Aspiration hazard | - | - | - | - | - | − |
| Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
|---|---|---|---|---|---|---|---|
| 11 | Hazardous to the aquatic environment （Acute） | - | - | - | - | - | − |
| 11 | Hazardous to the aquatic environment （Long-term） | - | - | - | - | - | − |
NOTE:
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* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference：
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Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website （in Japanese Only） |
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Model SDS by MHLW |
MHLW Website （in Japanese Only） |