Chemical Name:Methyl-endo-methylenetetrahydrophthalic anhydride
CAS:25134-21-8
ID: | 22A4194 |
Classifier: | Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE) |
Year Classified: | FY2010 |
Reference Manual: | GHS Classification Guidance by the Japanese Government (July, 2010) |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
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1 | Explosives | Not applicable | - | - | - | - | There are no chemical groups associated with explosive properties present in the molecule. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | - | Liquid at room temperature (Sax (11th, 2004)). |
3 | Aerosols | Not applicable | - | - | - | - | Not aerosol products. |
4 | Oxidizing gases | Not applicable | - | - | - | - | Liquid at room temperature (Sax (11th, 2004)). |
5 | Gases under pressure | Not applicable | - | - | - | - | Liquid at room temperature (Sax (11th, 2004)). |
6 | Flammable liquids | Not classified | - | - | - | - | Although measurement method of the flash point 135 degC (GESTIS (Access on Oct. 2010)) is unknown, it is estimated that the flash point measured by the closed-cup method is > 93 degC. Therefore, the substance is classified as "Not classified". |
7 | Flammable solids | Not applicable | - | - | - | - | Liquid at room temperature (Sax (11th, 2004)). |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
9 | Pyrophoric liquids | Not classified | - | - | - | - | Since its autoignition temperature is 450 degC (GESTIS (Access on Oct. 2010)), it is considered that the substance does not ignite at room temperature. |
10 | Pyrophoric solids | Not applicable | - | - | - | - | Liquid at room temperature (Sax (11th, 2004)). |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | - | Test methods applicable to liquid substances are not available. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | - | The chemical structure of the substance does not contain metals or metalloids (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
13 | Oxidizing liquids | Not applicable | - | - | - | - | The substance is an organic compound containing oxygen which is chemically bonded only to carbon or hydrogen. |
14 | Oxidizing solids | Not applicable | - | - | - | - | Liquid at room temperature (Sax (11th, 2004)). |
15 | Organic peroxides | Not applicable | - | - | - | - | Organic compounds containing no bivalent -O-O- structure. |
16 | Corrosive to metals | Classification not possible | - | - | - | - | No data available. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Category 4 | Warning | H302: Harmful if swallowed |
P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell. P264: Wash ... thoroughly after handling. P270: Do not eat, drink or smoke when using this product. P330: Rinse mouth. P501: Dispose of contents/container to ... |
Based on the rat LD50 value of 958 mg/kg (OECD Study, GLP-compliant) (RTECS (2009), original literature: HPV184 U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Cyclic Anhydrides. pdf (http://www. epa. gov/HPV/pubs/summaries/viewsrch. htm) : (2001)), the substance was classified as Category 4. | |
1 | Acute toxicity (Dermal) | Not classified | - | - | - | - | Based on the rat LD50 value of 4920 mg/kg bw and the rabbit LD50 value of > 2000 mg/kg (RTECS (2009), original literature: HPV184 U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Cyclic Anhydrides. pdf (http://www. epa. gov/HPV/pubs/summaries/viewsrch. htm) : (2001)), the substance was classified as "Not classified" in the JIS classification (corresponding to Category 5 in the UN-GHS classification). |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | - | Liquid at room temperature (Sax, 11th (2004)). |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | - | No data available. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | - | Insufficient data were available. The lethal concentration of 0.75 mg/L was reported based on the aerosol 4-hour exposure (RTECS (2009), original literature: HPV184 U.S. Environmental Protection Agency; High Production Volume (HPV) Challenge; Cyclic Anhydrides.pdf (http://www. epa. gov/HPV/pubs/summaries/viewsrch. htm) : (2001)). Since the value did not provide the basis for the classification, the classification was not possible. |
2 | Skin corrosion/irritation | Classification not possible | - | - | - | - | No data available. |
3 | Serious eye damage/eye irritation | Classification not possible | - | - | - | - | No data available. |
4 | Respiratory sensitization | Classification not possible | - | - | - | - | No data available. |
4 | Skin sensitization | Classification not possible | - | - | - | - | No data available. |
5 | Germ cell mutagenicity | Classification not possible | - | - | - | - | No data available. |
6 | Carcinogenicity | Classification not possible | - | - | - | - | No data available. |
7 | Reproductive toxicity | Classification not possible | - | - | - | - | No data available. |
8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | - | No data available. |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | - | No data available. |
10 | Aspiration hazard | Classification not possible | - | - | - | - | No data available. |
Hazard class | Classification | Symbol | Signal word | Hazard statement | Precautionary statement | Rationale for the classification | |
---|---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible | - | - | - | - | No data available. |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible | - | - | - | - | No data available. |
12 | Hazardous to the ozone layer | Classification not possible | - | - | - | - | This substance is not listed in Annexes to the Montreal Protocol. |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
Reference Manual |
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Definitions / Abbreviations |
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Model Label by MHLW |
MHLW Website (in Japanese Only) |
Model SDS by MHLW |
MHLW Website (in Japanese Only) |