GHS Classification Result

Chemical Name:O,O-Dimethyl dithiophosphate
CAS:756-80-9

Result:
ID: 22A4217
Classifier: Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
Year Classified: FY2010
Reference Manual: GHS Classification Guidance by the Japanese Government (July, 2010)

PHYSICAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - - There are no chemical groups associated with explosive properties present in the molecule.
2 Flammable gases (including chemically unstable gases) Not applicable - - - - Liquid at room temperature (Lide (90th, 2009))
3 Aerosols Not applicable - - - - Not aerosol products.
4 Oxidizing gases Not applicable - - - - Liquid at room temperature (Lide (90th, 2009))
5 Gases under pressure Not applicable - - - - Liquid at room temperature (Lide (90th, 2009))
6 Flammable liquids Category 4 - Warning H227: Combustible liquid P370+P378: In case of fire: Use ... for extinction.
P403+P235: Store in a well-ventilated place. Keep cool.
P210: Keep away from heat/sparks/open flames/hot surfaces. - No smoking.
P280: Wear protective gloves/protective clothing/eye protection/face protection.
P501: Dispose of contents/container to ...
Although measurement method of the flash point 92 degC (Ullmanns (E) (6th, 2003)) is unknown, it is estimated that the flash point measured by the closed-cup method fall within the range of > 60 degC and <= 93 degC. Therefore, the substance was classified into Category 4.
7 Flammable solids Not applicable - - - - Liquid at room temperature (Lide (90th, 2009))
8 Self-reactive substances and mixtures Not applicable - - - - There are no chemical groups present in the molecule associated with explosive or self-reactive properties.
9 Pyrophoric liquids Not classified - - - - Since its autoignition temperature is 114 - 115 degC (15710 Chemical Products (2010)), it is considered that the substance does not ignite at room temperature.
10 Pyrophoric solids Not applicable - - - - Liquid at room temperature (Lide (90th, 2009))
11 Self-heating substances and mixtures Classification not possible - - - - Test methods applicable to liquid substances are not available.
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - - Although the substance contains a metalloid (P), the water solubility data 5860 mg/L (SRC Phys Prop (Access on Nov. 2010)) is obtained. Therefore it is considered that the substance does not react vigorously with water.
13 Oxidizing liquids Classification not possible - - - - Classification is not possible since no data are available though the substance is an organic compound containing oxygen (but not fluorine or chlorine) which is chemically bonded to the elements other than carbon or hydrogen.
14 Oxidizing solids Not applicable - - - - Liquid at room temperature (Lide (90th, 2009))
15 Organic peroxides Not applicable - - - - Organic compounds containing no bivalent -O-O- structure
16 Corrosive to metals Classification not possible - - - - No data available.

HEALTH HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 4 Warning H302: Harmful if swallowed P301+P312: IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
P264: Wash ... thoroughly after handling.
P270: Do not eat, drink or smoke when using this product.
P330: Rinse mouth.
P501: Dispose of contents/container to ...
Based on the rat LD50 value of 694 mg/kg bw (RTECS (1999), original literature: National Technical Information Service. OTS0543903), the substance was classified as Category 4.
1 Acute toxicity (Dermal) Classification not possible - - - - No data available.
1 Acute toxicity (Inhalation: Gases) Not applicable - - - - Liquid at room temperature (Lide, 90th (2009)).
1 Acute toxicity (Inhalation: Vapours) Category 2 Danger H330: Fatal if inhaled P304+P340: IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing.
P403+P233: Store in a well-ventilated place. Keep container tightly closed.
P260: Do not breathe dust/fume/gas/mist/vapours/spray.
P271: Use only outdoors or in a well-ventilated area.
P284: Wear respiratory protection.
P310: Immediately call a POISON CENTER or doctor/physician.
P320: Specific treatment is urgent (see ... on this label).
P405: Store locked up.
P501: Dispose of contents/container to ...
Based on the rat LC50 value of 1700 mg/m3/4hrs (converted value as the concentration in the air: 263 ppm) (RTECS (1999), original literature: National Technical Information Service. OTS0537217), the substance was classified as Category 2. Since the test was carried out in the concentration of lower than 90% of the saturated vapor pressure concentration (3.15 mg/L = 487 ppm), the criterion values for gas were adopted.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - - No data available.
2 Skin corrosion/irritation Classification not possible - - - - The classification was not possible due to lack of data. As relevant information from the "List 3" information source designated in the GHS classification guidance for the Japanese government, moderate irritation was reported in the Draize tests by the 24-hour application using rabbits (RTECS (1999)).
3 Serious eye damage/eye irritation Classification not possible - - - - The classification was not possible due to lack of data. As relevant information from the "List 3" information source designated in the GHS classification guidance for the Japanese government, severe irritation was reported in the Draize test using rabbit (RTECS (1999)).
4 Respiratory sensitization Classification not possible - - - - No data available.
4 Skin sensitization Classification not possible - - - - No data available.
5 Germ cell mutagenicity Classification not possible - - - - No data available.
6 Carcinogenicity Classification not possible - - - - No data available.
7 Reproductive toxicity Classification not possible - - - - No data available.
8 Specific target organ toxicity - Single exposure Classification not possible - - - - No data available.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - - No data available.
10 Aspiration hazard Classification not possible - - - - No data available.

ENVIRONMENTAL HAZARDS
Hazard class Classification Symbol Signal word Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 3 - - H402: Harmful to aquatic life P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
Classified into Category 3 from its 96h-LC50 = 17 mg/L for fish (Umbra pygmaea) (AQUIRE, 2011).
11 Hazardous to the aquatic environment (Long-term) Category 3 - - H412: Harmful to aquatic life with long lasting effects P273: Avoid release to the environment.
P501: Dispose of contents/container to ...
Classified into Category 3 since its acute toxicity is Category 3 and it is not rapidly degradable (BIOWIN).
12 Hazardous to the ozone layer Classification not possible - - - - This substance is not listed in Annexes to the Montreal Protocol.


NOTE:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.

Reference:
Reference Manual

Definitions / Abbreviations

Model Label by MHLW

MHLW Website (in Japanese Only)

Model SDS by MHLW

MHLW Website (in Japanese Only)


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