Item | Information |
---|---|
CAS number | 5435-64-3 |
Chemical name | 3,5,5-Trimethylhexanal |
Substance ID | 23A5040 |
Fiscal year of classification conducted | FY2011 |
Classifier(s) (Ministries) | Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE) |
New/Revised | New |
Download in Excel format | Excel file |
Item | Information |
---|---|
Guidance used for classification (External link) |
Physical Hazards & Health Hazards: GHS Classification Guidance by the Japanese Government (July, 2010)
Environmental Hazards: UN GHS Document (4th revised edition) |
Definitions / Abbreviations (Excel file) | Definitions / Abbreviations |
Model Label by MHLW (External link) | MHLW Website (in Japanese Only) |
Model SDS by MHLW (External link) | MHLW Website (in Japanese Only) |
OECD/eChemPortal (External link) | eChemPortal |
Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Explosives | Not applicable | - | - | - | There are no chemical groups associated with explosive properties present in the molecule. |
2 | Flammable gases (including chemically unstable gases) | Not applicable | - | - | - | "Liquids" according to GHS definition. |
3 | Aerosols | Not applicable | - | - | - | Not an aerosol product. |
4 | Oxidizing gases | Not applicable | - | - | - | "Liquids" according to GHS definition. |
5 | Gases under pressure | Not applicable | - | - | - | "Liquids" according to GHS definition. |
6 | Flammable liquids | Category 3 |
H226 |
P303+P361+P353 P370+P378 P403+P235 P210 P233 P240 P241 P242 P243 P280 P501 |
A flash point of 45 degrees C [closed-cup] (IUCLID (2000)), which is >= 23 degrees C and <= 60 degrees C, corresponds to Category 3. | |
7 | Flammable solids | Not applicable | - | - | - | "Liquids" according to GHS definition. |
8 | Self-reactive substances and mixtures | Not applicable | - | - | - | There are no chemical groups present in the molecule associated with explosive or self-reactive properties. |
9 | Pyrophoric liquids | Not classified | - | - | - | It is conceivable that it does not ignite at normal temperatures from an ignition point of 245 degrees C (IUCLID (2000)). |
10 | Pyrophoric solids | Not applicable | - | - | - | "Liquids" according to GHS definition. |
11 | Self-heating substances and mixtures | Classification not possible | - | - | - | No established test method suitable for liquid substances. |
12 | Substances and mixtures which, in contact with water, emit flammable gases | Not applicable | - | - | - | Not containing metals or semimetals (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At). |
13 | Oxidizing liquids | Not applicable | - | - | - | An organic compound that contains oxygen which is not chemically bonded to elements other than carbon. |
14 | Oxidizing solids | Not applicable | - | - | - | "Liquids" according to GHS definition. |
15 | Organic peroxides | Not applicable | - | - | - | An organic compound that does not contain -O-O- structure. |
16 | Corrosive to metals | Classification not possible | - | - | - | No data. |
Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
---|---|---|---|---|---|---|
1 | Acute toxicity (Oral) | Not classified | - | - | - | On the basis of an LD50 value of 3240 mg/kg bw for rats (JECFA FAS 40 (1998)), it was classified as "Not classified" in JIS classification (corresponding to Category 5 in UN GHS classification). |
1 | Acute toxicity (Dermal) | Not classified | - | - | - | On the basis of an LD50 value of > 2500 mg/kg bw for rats (IUCLID (2000)), it was classified as "Not classified" in JIS classification (corresponding to Category 5 or "Not classified" in UN GHS classification). |
1 | Acute toxicity (Inhalation: Gases) | Not applicable | - | - | - | "Liquids" according to GHS definition. |
1 | Acute toxicity (Inhalation: Vapours) | Classification not possible | - | - | - | No data. |
1 | Acute toxicity (Inhalation: Dusts and mists) | Classification not possible | - | - | - | No data. |
2 | Skin corrosion/irritation | Category 2 |
H315 |
P302+P352 P332+P313 P264 P280 P321 P362 |
On the basis of "irritating" in a semi-occlusive test applied a nonyl aldehyde mixture containing 90% of this substance to rabbit skins (OECD TG404, GLP) (IUCLID (2000)) and "moderately irritating" in a test applied this substance for 24 hours (HSDB (2009)), it was classified in Category 2. | |
3 | Serious eye damage/eye irritation | Category 2B |
|
H320 |
P305+P351+P338 P337+P313 P264 |
On the basis of "slightly irritating" in a test applied a nonyl aldehyde mixture containing 90% of this substance to rabbit eyes (OECD TG405, GLP) (IUCLID (2000)), it was classified in Category 2B. |
4 | Respiratory sensitization | Classification not possible | - | - | - | No data. |
4 | Skin sensitization | Classification not possible | - | - | - |
A sensitization test using 25 subjects reported not sensitizing (Magnusson & Kligman method) (IUCLID (2000)), but further details are unknown. Besides, in a human repeated insult patch test, it was assessed as possibly sensitizing because 5 out of 39 subjects (12.8%) showed reactions and 10 out of 39 subjects (25.6%) showed weak reactions to a 25% ethanol solution of a test substance, while it was assessed as not sensitizing because 0 out of 42 subjects showed reactions to 1.25% ethanol solution. (IUCLID (2000)) From the above test results, it was classified as "Classification not possible" due to no clear conclusion on a skin sensitization. |
5 | Germ cell mutagenicity | Classification not possible | - | - | - | No data. |
6 | Carcinogenicity | Classification not possible | - | - | - | No data. |
7 | Reproductive toxicity | Classification not possible | - | - | - | No data. |
8 | Specific target organ toxicity - Single exposure | Classification not possible | - | - | - | No data. |
9 | Specific target organ toxicity - Repeated exposure | Classification not possible | - | - | - | No data. |
10 | Aspiration hazard | Classification not possible | - | - | - | No data. |
Hazard class | Classification |
Pictogram (Code: symbol) Signal word |
Code (Hazard statement) |
Code (Precautionary statement) |
Rationale for the classification | |
---|---|---|---|---|---|---|
11 | Hazardous to the aquatic environment (Acute) | Classification not possible | - | - | - | No data. |
11 | Hazardous to the aquatic environment (Long-term) | Classification not possible | - | - | - | No data. |
12 | Hazardous to the ozone layer | Classification not possible | - | - | - | This substance is not listed in Annexes to the Montreal Protocol. |
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users. * This is a provisional English translation of classification results and is subject to revision without notice. * The responsibility for any resulting GHS labelling and SDS referenced from this site is with users. |
2016/8/17 Addition of Rationale for the classification |