GHS Classification Result

日本語で表示

GENERAL INFORMATION

Item Information
CAS number 3391-86-4
Chemical name 1-Octen-3-ol
Substance ID 23A5060
Fiscal year of classification conducted FY2011
Classifier(s) (Ministries) Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
New/Revised New
Download in Excel format Excel file

REFERENCE INFORMATION

Item Information
Guidance used for classification (External link) Physical Hazards & Health Hazards: GHS Classification Guidance by the Japanese Government (July, 2010)
Environmental Hazards: UN GHS Document (4th revised edition)
Definitions / Abbreviations (Excel file) Definitions / Abbreviations
Model Label by MHLW (External link) MHLW Website (in Japanese Only)
Model SDS by MHLW (External link) MHLW Website (in Japanese Only)
OECD/eChemPortal (External link) eChemPortal

PHYSICAL HAZARDS

Hazard class Classification Symbol
Signal word
Hazard statement Precautionary statement Rationale for the classification
1 Explosives Not applicable - - - There are no chemical groups associated with explosive properties present in the molecule.
2 Flammable gases (including chemically unstable gases) Not applicable - - - "Liquids" according to GHS definition.
3 Aerosols Not applicable - - - Not an aerosol product.
4 Oxidizing gases Not applicable - - - "Liquids" according to GHS definition.
5 Gases under pressure Not applicable - - - "Liquids" according to GHS definition.
6 Flammable liquids Category 4
Warning
H227
P370+P378
P403+P235
P210
P280
P501
Sixty-eight degrees C [closed cup] (MSDS (Sigma-Aldrich) (Access in June. 2011) is > 60 degrees C and <= 93 degrees C, therefore, it corresponds to Category 4.
7 Flammable solids Not applicable - - - "Liquids" according to GHS definition.
8 Self-reactive substances and mixtures Classification not possible - - - There is a chemical group present in the molecule associated with a self-reactive property (unsaturated bond), but the classification is not possible due to no data.
9 Pyrophoric liquids Classification not possible - - - No data.
10 Pyrophoric solids Not applicable - - - "Liquids" according to GHS definition.
11 Self-heating substances and mixtures Classification not possible - - - No established test method suitable for liquid substances.
12 Substances and mixtures which, in contact with water, emit flammable gases Not applicable - - - Not containing metals or semimetals (B, Si, P, Ge, As, Se, Sn, Sb, Te, Bi, Po, At).
13 Oxidizing liquids Not applicable - - - An organic compound that contains oxygen which is not chemically bonded to elements other than carbon or hydrogen.
14 Oxidizing solids Not applicable - - - "Liquids" according to GHS definition.
15 Organic peroxides Not applicable - - - An organic compound that does not contain -O-O- structure.
16 Corrosive to metals Classification not possible - - - No data.

HEALTH HAZARDS

Hazard class Classification Symbol
Signal word
Hazard statement Precautionary statement Rationale for the classification
1 Acute toxicity (Oral) Category 4

Warning
H302
P301+P312
P264
P270
P330
P501
On the basis of an LD50 value of 340 mg/kg for rats (JECFA 1067 (2003)), it was classified in Category 4.
1 Acute toxicity (Dermal) Not classified - - - An LD50 value of 3300 mg/kg for rabbits (KemI-Riskline (2007), corresponding to List2) corresponds to "Not classified" in JIS classification (Category 5 in UN GHS classification).
1 Acute toxicity (Inhalation: Gases) Not applicable - - - "Liquids" according to GHS definition.
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - No data.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - No data.
2 Skin corrosion/irritation Classification not possible - - - No data.
3 Serious eye damage/eye irritation Classification not possible - - - No data.
4 Respiratory sensitization Classification not possible - - - No data.
4 Skin sensitization Classification not possible - - - No data.
5 Germ cell mutagenicity Classification not possible - - - The classification is not possible due to no in vivo data.
Besides, negatives as in vitro tests in both an HPRT assay using Chinese hamster V-79 cells and a micronucleus test using V-79 fibroblasts (KemI-Riskline (2007)) are reported.
6 Carcinogenicity Classification not possible - - - No data.
7 Reproductive toxicity Classification not possible - - - No data.
8 Specific target organ toxicity - Single exposure Category 3 (Respiratory tract irritation)

Warning
H335
P304+P340
P403+P233
P261
P271
P312
P405
P501
Irritation to nose and throat was reported in an exposure of 10 mg/m3 concentration of this substance to 30 human subjects for 2 hours (KemI-Riskline (2007)), on the other hand, a respiratory depression was observed in irritation at the low concentrations such as an RD50 value (concentration associated with a 50 % decrease in the respiratory rate) of 182 mg/m3 for mice for this substance in an animal test (KemI-Riskline (2007)), therefore, it was classified in Category 3 (respiratory tract irritation).
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - A 90-day diet administration test in which rats were given only one dose (doses: 12 mg/kg bw/day (males), 14 mg/kg bw/day (females)) reports no effects on test substance administration, and NOELs of 12 mg/kg/day in males and 14 mg/kg/day in females (JECFA 1067 (2003)).
But it was classified as "Classification not possible" because the doses are within a range of guidance values and effects near an upper limit of guidance values are unknown.
10 Aspiration hazard Classification not possible - - - No data.

ENVIRONMENTAL HAZARDS

Hazard class Classification Symbol
Signal word
Hazard statement Precautionary statement Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Classification not possible - - - No data.
11 Hazardous to the aquatic environment (Long-term) Classification not possible - - - No data.
12 Hazardous to the ozone layer Classification not possible - - - This substance is not listed in Annexes to the Montreal Protocol.


NOTES:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government, and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.



Updated date:
2016/7/13 Addition of Rationale for the classification

List of GHS Classification Results