GHS Classification Result

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GENERAL INFORMATION

Item Information
CAS number 7681-55-2
Chemical name Sodium iodate
Substance ID 23A5153
Fiscal year of classification conducted FY2011
Classifier(s) (Ministries) Ministry of Health, Labour and Welfare (MHLW), Ministry of the Environment (MOE)
New/Revised New
Download in Excel format Excel file

REFERENCE INFORMATION

Item Information
Guidance used for classification (External link) Physical Hazards & Health Hazards: GHS Classification Guidance by the Japanese Government (July, 2010)
Environmental Hazards: UN GHS Document (4th revised edition)
Definitions / Abbreviations (Excel file) Definitions / Abbreviations
Model Label by MHLW (External link) MHLW Website (in Japanese Only)
Model SDS by MHLW (External link) MHLW Website (in Japanese Only)
OECD/eChemPortal (External link) eChemPortal

PHYSICAL HAZARDS

Hazard class Classification Pictogram
(Code: symbol)
Signal word
Code
(Hazard statement)
Code
(Precautionary statement)
Rationale for the classification
1 Explosives Not classified - - - It contains chemical groups associated with an explosive property (O-halogen), but it is classified as "Not classified" due to an inorganic compound.
2 Flammable gases (including chemically unstable gases) Not applicable - - - "Solids" according to GHS definition.
3 Aerosols Not applicable - - - Not an aerosol product.
4 Oxidizing gases Not applicable - - - "Solids" according to GHS definition.
5 Gases under pressure Not applicable - - - "Solids" according to GHS definition.
6 Flammable liquids Not applicable - - - "Solids" according to GHS definition.
7 Flammable solids Not classified - - - Not combustible but enhances combustion of other substances (CICAD 72 (2009)).
8 Self-reactive substances and mixtures Not applicable - - - It is classified as an oxidizing substance.
9 Pyrophoric liquids Not applicable - - - "Solids" according to GHS definition.
10 Pyrophoric solids Not classified - - - Not combustible but enhances combustion of other substances (CICAD 72 (2009)).
11 Self-heating substances and mixtures Classification not possible - - - No established test method suitable for solid substances with a melting point of 140 degrees C or lower.
12 Substances and mixtures which, in contact with water, emit flammable gases Not classified - - - It contains a metal (Na), but it is conceivable that it does not react vigorously with water from data on water solubility as 9.47 g/100 g H2O (25 degrees C) (CRC (91st, 2010)).
13 Oxidizing liquids Not applicable - - - "Solids" according to GHS definition.
14 Oxidizing solids Category 2

Danger
H272
P370+P378
P210
P220
P221
P280
P501
It is an inorganic compound which contains oxygen and halogen (iodine), but from the information that "may react violently with organic matter" (Sax (11th, 2004)), and from the information that "THESE MATERIALS ARE A MODERATE FIRE HAZARD BECAUSE THEY ARE POWERFUL OXIDIZERS. IN CONTACT WITH FLAMMABLE OR EVEN COMBUSTIBLE MATERIALS THEY CAN START FIRES." (HSDB (2002)), it was judged to be an oxidizer.
Furthermore, from classification 'UN1497 class 5.1' (Handbook on Accidental Mixing Hazards of Chemicals (second edition, 1997)) and being distributed with UN1497PGII according to MSDS (Sigma-Aldrich), it was classified in Category 2.
15 Organic peroxides Not applicable - - - It is an inorganic compound.
16 Corrosive to metals Classification not possible - - - No established test method suitable for solid substances.

HEALTH HAZARDS

Hazard class Classification Pictogram
(Code: symbol)
Signal word
Code
(Hazard statement)
Code
(Precautionary statement)
Rationale for the classification
1 Acute toxicity (Oral) Category 4

Warning
H302
P301+P312
P264
P270
P330
P501
On the basis of an LD50 value of 505 mg/kg bw for mice (RTECS (2007)): original literature Journal of Pharmacology and Experimental Therapeutics. 120, 171, 1957) confirmed by the original literature, it was classified in Category 4.
1 Acute toxicity (Dermal) Classification not possible - - - No data.
1 Acute toxicity (Inhalation: Gases) Not applicable - - - "Solids" according to GHS definition.
1 Acute toxicity (Inhalation: Vapours) Classification not possible - - - No data.
1 Acute toxicity (Inhalation: Dusts and mists) Classification not possible - - - No data.
2 Skin corrosion/irritation Classification not possible - - - No data.
3 Serious eye damage/eye irritation Classification not possible - - - No data.
4 Respiratory sensitization Classification not possible - - - No data.
4 Skin sensitization Classification not possible - - - Lack of data.
Besides, Japan Society for Occupational Health designates iodine or its compound as a sensitizing substance (skin; Group 2) with notice that not all substances are identified. (The Recommendation of Acceptable Concentration of the Japan Society for Occupational Health (2011))
5 Germ cell mutagenicity Not classified - - - On the basis of a negative in a micronucleus test using mouse bone marrow cells (in vivo somatic cell mutagenicity test) (CICAD 72 (2009)), it was classified as "Not classified."
Besides, an Ames test in an in vitro test reported a negative. (CICAD 72 (2009))
6 Carcinogenicity Classification not possible - - - No data.
7 Reproductive toxicity Classification not possible - - - No data.
8 Specific target organ toxicity - Single exposure Classification not possible - - - No data.
9 Specific target organ toxicity - Repeated exposure Classification not possible - - - Because repeated administration of sodium iodate (equivalent to 0.3099 mg/kg bw/day of potassium iodate) to rabbits for 4 to 14 months reported no adverse effects (JECFA 57 (1966)) with unknown details, it was classified as "Classification not possible" due to lack of data.
10 Aspiration hazard Classification not possible - - - No data.

ENVIRONMENTAL HAZARDS

Hazard class Classification Pictogram
(Code: symbol)
Signal word
Code
(Hazard statement)
Code
(Precautionary statement)
Rationale for the classification
11 Hazardous to the aquatic environment (Acute) Category 3 - H402
P273
P501
From 48-hour EC50 = 54.8 mg/L for crustacea (Daphnia magna) (AQUIRE, 2012), it was classified in Category 3.
11 Hazardous to the aquatic environment (Long-term) Category 3 - H412
P273
P501
Reliable chronic toxicity data were not obtained.
Because behavior in water is unknown as an inorganic compound and it was classified in Category 3 in acute toxicity, it was classified in Category 3.
12 Hazardous to the ozone layer Classification not possible - - - This substance is not listed in Annexes to the Montreal Protocol.


NOTES:
* Classification was conducted by relevant Japanese Ministries in accordance with GHS Classification Guidance for the Japanese Government,
   and is intended to provide a reference for preparing GHS labelling and SDS for users.
* This is a provisional English translation of classification results and is subject to revision without notice.
* The responsibility for any resulting GHS labelling and SDS referenced from this site is with users.



Updated date:
2016/10/13 Addition of Rationale for the classification

List of GHS Classification Results